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Atropa Belladonna
''Atropa bella-donna'', commonly known as deadly nightshade or belladonna, is a toxic perennial herbaceous plant in the nightshade family Solanaceae, which also includes tomatoes, potatoes and eggplant. It is native to Europe and Western Asia, including Turkey, its distribution extending from England in the west to western Ukraine and the Iranian province of Gilan in the east. It is also naturalised or introduced in some parts of Canada, North Africa and the United States. The foliage and berries are extremely toxic when ingested, containing tropane alkaloids. It can also be harmful to handle and/or touch these plants. These toxins include atropine, scopolamine, and hyoscyamine, which cause delirium and hallucinations, and are also used as pharmaceutical anticholinergics. Tropane alkaloids are of common occurrence not only in the Old World tribes Hyoscyameae (to which the genus Atropa belongs) and Mandragoreae, but also in the New World tribe Datureae—all of which bel ...
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Carl Linnaeus
Carl Linnaeus (23 May 1707 – 10 January 1778), also known after ennoblement in 1761 as Carl von Linné,#Blunt, Blunt (2004), p. 171. was a Swedish biologist and physician who formalised binomial nomenclature, the modern system of naming organisms. He is known as the "father of modern Taxonomy (biology), taxonomy". Many of his writings were in Latin; his name is rendered in Latin as and, after his 1761 ennoblement, as . Linnaeus was the son of a curate and was born in Råshult, in the countryside of Småland, southern Sweden. He received most of his higher education at Uppsala University and began giving lectures in botany there in 1730. He lived abroad between 1735 and 1738, where he studied and also published the first edition of his ' in the Netherlands. He then returned to Sweden where he became professor of medicine and botany at Uppsala. In the 1740s, he was sent on several journeys through Sweden to find and classify plants and animals. In the 1750s and 1760s, he co ...
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Berry (botany)
In botany, a berry is a fleshy fruit without a drupe, drupe (pit) produced from a single flower containing one Ovary (botany), ovary. Berries so defined include grapes, Ribes, currants, and tomatoes, as well as cucumbers, eggplants (aubergines), persimmons and bananas, but exclude certain fruits that meet the berry, culinary definition of berries, such as strawberries and raspberries. The berry is the most common type of fleshy fruit in which the entire outer layer of the ovary wall ripens into a potentially edible "pericarp". Berries may be formed from one or more gynoecium, carpels from the same flower (i.e. from a simple or a compound ovary). The seeds are usually embedded in the fleshy interior of the ovary, but there are some non-fleshy exceptions, such as ''Capsicum'' species, with air rather than pulp around their seeds. Many berries are edible, but others, such as the Potato fruit, fruits of the potato and the deadly nightshade, are poisonous to humans. A plant that be ...
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Datureae
Daturae is a tribe of flowering plants in the subfamily Solanoideae of the family Solanaceae. It comprises three genera: ''Datura'', the Devil's trumpets, ''Brugmansia'', the Angel's trumpets, and the monotypic '' Trompettia''. These plants are all genetically related. Phylogenetic research shows that Datura species evolved out of an ancestor shared with Nicotiana Tabacum ''Nicotiana tabacum'', or cultivated tobacco, is an annually grown herbaceous plant of the genus ''Nicotiana''. ''N. tabacum'' is the most commonly grown species in the genus ''Nicotiana,'' as the plant's leaves are commercially harvested to be .... Whether or not Datura and Brugmansia species evolved out of each other is disputed. Genera References External links * * Solanoideae Asterid tribes {{Solanales-stub ...
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New World
The term "New World" is used to describe the majority of lands of Earth's Western Hemisphere, particularly the Americas, and sometimes Oceania."America." ''The Oxford Companion to the English Language'' (). McArthur, Tom, ed., 1992. New York: Oxford University Press, p. 33: "[16c: from the feminine of ''Americus'', the Latinized first name of the explorer Amerigo Vespucci (1454–1512). The name ''America'' first appeared on a map in 1507 by the German cartographer Martin Waldseemüller, referring to the area now called Brazil]. Since the 16th century, the term "New World" has been used to describe the Western Hemisphere, often referred to as the Americas. Since the 18th century, it has come to represent the United States, which was initially colonial British America until it established independence following the American Revolutionary War. The second sense is now primary in English: ... However, the term is open to uncertainties: ..." The term arose in the early 16th ...
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Mandragoreae
''Mandragora'' is a plant genus belonging to the nightshade family (Solanaceae). Members of the genus are known as mandrakes. Between three and five species are placed in the genus. The one or two species found around the Mediterranean constitute the mandrake of ancient writers such as Dioscorides. Two or three further species are found eastwards into China. All are perennial herbaceous plants, with large tap roots and leaves in the form of a rosette. Individual flowers are bell-shaped, whitish through to violet, and followed by yellow or orange berries. Like many members of the Solanaceae, species of ''Mandragora'' contain highly biologically active alkaloids that make the plants poisonous. Their roots in particular have a long use in traditional medicine. Mandrakes are involved in many myths and superstitions. Description Species of ''Mandragora'' are perennial herbaceous plants. They have large vertical tap roots, sometimes forked. Their stems are short or virtually absent. ...
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Hyoscyameae
Hyoscyameae is an Old World Tribe (biology), tribe of the subfamily Solanoideae of the flowering plant family Solanaceae. It comprises seven genera: ''Anisodus'', ''Atropa'', ''Atropanthe'', ''Hyoscyamus'', ''Physochlaina'', ''Przewalskia'' and ''Scopolia''. The genera ''Atropanthe'' and ''Przewalskia'' are monotypic, the first being endemic to China and the second to Tibet. All seven genera of the tribe are poisonous and have a long tradition of use as medicinal plants, being rich in tropane alkaloids with anticholinergic properties. Furthermore, the genera ''Atropa'', ''Hyoscyamus'', ''Scopolia'' and ''Physochlaina'' have furnished entheogens - the first three in the historical context of European witchcraft and, more specifically, of the flying ointments employed in such practices, while the similar chemistry of the remaining genera points to the potential for entheogenic use. Six of the genera have dry, pyxidial fruits i.e. capsules dehiscing by an Operculum (botany), operculu ...
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Old World
The "Old World" () is a term for Afro-Eurasia coined by Europeans after 1493, when they became aware of the existence of the Americas. It is used to contrast the continents of Africa, Europe, and Asia in the Eastern Hemisphere, previously thought of by the Europeans as comprising the entire world, with the "New World", a term for the newly encountered lands of the Western Hemisphere, particularly the Americas. Etymology In the context of archaeology and world history, the term "Old World" includes those parts of the world which were in (indirect) cultural contact from the Bronze Age onwards, resulting in the parallel development of the early civilizations, mostly in the temperate zone between roughly the 45th and 25th parallels north, in the area of the Mediterranean, including North Africa. It also included Mesopotamia, the Persian plateau, the Indian subcontinent, China, and parts of Sub-Saharan Africa. These regions were connected via the Silk Road trade route, and ...
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Anticholinergic
Anticholinergics (anticholinergic agents) are substances that block the action of the acetylcholine (ACh) neurotransmitter at synapses in the central nervous system, central and peripheral nervous system. These agents inhibit the parasympathetic nervous system by selectively blocking the binding of ACh to its receptor in nerve cells. The nerve fibers of the parasympathetic system are responsible for the involuntary movement of Smooth muscle tissue, smooth muscles present in the gastrointestinal tract, urinary tract, lungs, sweat glands, and many other parts of the body. In broad terms, anticholinergics are divided into two categories in accordance with their specific targets in the central and peripheral nervous system and at the neuromuscular junction: antimuscarinic agents and antinicotinic agents (ganglionic blockers, neuromuscular blockers). The term "anticholinergic" is typically used to refer to antimuscarinics that competitively inhibit the binding of ACh to muscarinic a ...
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Hallucination
A hallucination is a perception in the absence of an external stimulus that has the compelling sense of reality. They are distinguishable from several related phenomena, such as dreaming ( REM sleep), which does not involve wakefulness; pseudohallucination, which does not mimic real perception, and is accurately perceived as unreal; illusion, which involves distorted or misinterpreted real perception; and mental imagery, which does not mimic real perception, and is under voluntary control. Hallucinations also differ from " delusional perceptions", in which a correctly sensed and interpreted stimulus (i.e., a real perception) is given some additional significance. Hallucinations can occur in any sensory modality— visual, auditory, olfactory, gustatory, tactile, proprioceptive, equilibrioceptive, nociceptive, thermoceptive and chronoceptive. Hallucinations are referred to as multimodal if multiple sensory modalities occur. A mild form of hallucination is known as ...
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Delirium
Delirium (formerly acute confusional state, an ambiguous term that is now discouraged) is a specific state of acute confusion attributable to the direct physiological consequence of a medical condition, effects of a psychoactive substance, or multiple causes, which usually develops over the course of hours to days. As a syndrome, delirium presents with disturbances in attention, awareness, and higher-order cognition. People with delirium may experience other neuropsychiatric disturbances including changes in psychomotor activity (e.g., hyperactive, hypoactive, or mixed level of activity), disrupted sleep-wake cycle, emotional disturbances, disturbances of consciousness, or altered state of consciousness, as well as perceptual disturbances (e.g., hallucinations and delusions), although these features are not required for diagnosis. Diagnostically, delirium encompasses both the syndrome of acute confusion and its underlying organic process known as an acute encephalopathy. ...
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Hyoscyamine
Hyoscyamine (also known as daturine or duboisine) is a naturally occurring tropane alkaloid and plant toxin. It is a secondary metabolite found in certain plants of the family Solanaceae, including Hyoscyamus niger, henbane, Mandragora officinarum, mandrake, Brugmansia, angel's trumpets, Datura stramonium, jimsonweed, Latua pubiflora, the sorcerers' tree, and Atropa belladonna (deadly nightshade). It is the levorotary isomer of atropine (third of the three major nightshade alkaloids) and thus sometimes known as levo-atropine. In 2021, it was the 272nd most commonly prescribed medication in the United States, with more than 900,000 prescriptions. Medical uses Hyoscyamine is used to provide symptomatic relief of spasms caused by various lower abdominal and bladder disorders including peptic ulcers, irritable bowel syndrome, diverticulitis, pancreatitis, colic, and interstitial cystitis. It has also been used to relieve some heart problems, control some of the symptoms of Parkinso ...
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Scopolamine
Scopolamine, also known as hyoscine, or Devil's Breath, is a medication used to treat motion sickness and postoperative nausea and vomiting. It is also sometimes used before surgery to decrease saliva. When used by injection, effects begin after about 20 minutes and last for up to 8 hours. It may also be used orally and as a transdermal patch since it has been long known to have transdermal bioavailability. Scopolamine is in the antimuscarinic family of drugs and works by blocking some of the effects of acetylcholine within the nervous system. Scopolamine was first written about in 1881 and started to be used for anesthesia around 1900. Scopolamine is also the main active component produced by certain plants of the nightshade family, which historically have been used as psychoactive drugs, known as '' deliriants'', due to their antimuscarinic-induced hallucinogenic effects in higher doses. In these contexts, its mind-altering effects have been utilized for recre ...
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