Aglaia Silvestris
''Aglaia silvestris'' is a species of plant in the family Meliaceae. It is found in Cambodia, India, Indonesia, Malaysia, Papua New Guinea, the Philippines, the Solomon Islands, Thailand, and Vietnam. This plant initiated the naming of the Rocaglamide Rocaglamide is a natural product which belongs to a class of molecules called flavaglines. This compound was isolated in 1982 by Ming-Lu King (金明儒) and colleagues based on its antileukemic activity. The name of Rocaglamide is named from tw ... derivatives silvestrol and episilvestrol. In fact they were derived from the fruits and twigs of '' Aglaia foveolata''. References silvestris Near threatened plants Taxonomy articles created by Polbot {{Meliaceae-stub ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Herbarium
A herbarium (plural: herbaria) is a collection of preserved plant biological specimen, specimens and associated data used for scientific study. The specimens may be whole plants or plant parts; these will usually be in dried form mounted on a sheet of paper (called ''exsiccatum'', plur. ''exsiccata'') but, depending upon the material, may also be stored in boxes or kept in alcohol or other preservative. The specimens in a herbarium are often used as reference material in describing plant taxon, taxa. Some specimens may be Type (botany), types, some may be specimens distributed in published series called exsiccata, exsiccatae. The term herbarium is often used in mycology to describe an equivalent collection of preserved fungi, otherwise known as a fungarium. A xylarium is a herbarium specialising in specimens of wood. The term hortorium (as in the Liberty Hyde Bailey, Liberty Hyde Bailey Hortorium) has occasionally been applied to a herbarium specialising in preserving material of ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Thailand
Thailand, officially the Kingdom of Thailand and historically known as Siam (the official name until 1939), is a country in Southeast Asia on the Mainland Southeast Asia, Indochinese Peninsula. With a population of almost 66 million, it spans . Thailand Template:Borders of Thailand, is bordered to the northwest by Myanmar, to the northeast and east by Laos, to the southeast by Cambodia, to the south by the Gulf of Thailand and Malaysia, and to the southwest by the Andaman Sea; it also shares maritime borders with Vietnam to the southeast and Indonesia and India to the southwest. Bangkok is the state capital and List of municipalities in Thailand#Largest cities by urban population, largest city. Tai peoples, Thai peoples migrated from southwestern China to mainland Southeast Asia from the 6th to 11th centuries. Greater India, Indianised kingdoms such as the Mon kingdoms, Mon, Khmer Empire, and Monarchies of Malaysia, Malay states ruled the region, competing with Thai states s ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Aglaia
Aglaia, Aglaea, Aglaïa, Aglaja, or Aglaya (Ἀγλαΐα) is an ancient Greek female name and may refer to: People and mythical figures * Aglaia or Aglaea (mythology) ** Aglaia (Grace), one of the Charites in Greek mythology * Saint Aglaia of Rome, 4th century, a companion of Saint Boniface of Tarsus Science * ''Aglaia'' (plant), a genus of trees in the mahogany family * ''Drosophila aglaia'', an endangered species of fly from Hawaii * The butterfly genus ''Aglais'' (Dalman, 1816) * 47 Aglaja, an asteroid Theatre * ', a ballet by Filippo Taglioni. * ''Aglaia'', an opera by Heitor Villa-Lobos Other uses * Aglaia (given name) * , an 18th-century British ship See also * Aglaja (other) Aglaja may refer to: *An alternative form of Aglaia (given name) ** Aglaja Brix (born 1990), German actress ** Aglaja Orgeni (1841–1926), Hungarian opera singer ** Aglaya, a character in Dostoyevski's novel ''The Idiot'' * ''Aglaja'', 1893 oper ... * Aglae (other) ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Aglaia Foveolata
''Aglaia foveolata'' is a species of tropical tree in the family Meliaceae. This plant occurs in Brunei, Indonesia, and Malaysia. It produces edible fruit. The bark contains silvestrol which is a potent inhibitor of ebola virus and Zika Virus Zika virus (ZIKV; pronounced or ) is a member of the virus family ''Flaviviridae''. It is spread by daytime-active ''Aedes'' mosquitoes, such as '' A. aegypti'' and '' A. albopictus''. Its name comes from the Ziika Forest of Uganda, where ... replication. References foveolata Near threatened plants Taxonomy articles created by Polbot {{Meliaceae-stub ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Silvestrol
Silvestrol is a natural product from the flavagline family, with a cyclopenta benzofuran core structure and an unusual dioxane ether side chain, which is found in the bark of trees from the genus ''Aglaia'', especially ''Aglaia silvestris'' and ''Aglaia foveolata''. Bioactivity It acts as a potent and selective inhibitor of the RNA helicase enzyme eIF4A, and has both broad-spectrum antiviral activity against diseases such as Ebola and coronaviruses, and anti-cancer properties, which makes it of considerable interest in medical research. However, as it cannot be extracted from tree bark in commercial amounts and is prohibitively complex to produce synthetically, practical applications have focused more on structurally simplified analogues such as CR-31-B. See also * Rocaglamide Rocaglamide is a natural product which belongs to a class of molecules called flavaglines. This compound was isolated in 1982 by Ming-Lu King (金明儒) and colleagues based on its antileukemic ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Rocaglamide
Rocaglamide is a natural product which belongs to a class of molecules called flavaglines. This compound was isolated in 1982 by Ming-Lu King (金明儒) and colleagues based on its antileukemic activity. The name of Rocaglamide is named from two parts: Roc- and aglamide. Roc- means Republic of China (中華民國), where this product was first isolated; aglamide indicates this product is isolated from Large-leaved ''Aglaia'' (Scientific name: '' Aglaia rimosa'' Rocaglamide was first synthesized by Barry Trost in 1990. Although other syntheses have been described since, Trost’s remains the only one to afford rocaglamide in an enantio-specific manner. See also * FL3 (flavagline) *Eukaryotic translation *eIF4A The eukaryotic initiation factor-4A (eIF4A) family consists of 3 closely related proteins EIF4A1, EIF4A2, and EIF4A3. These factors are required for the binding of Messenger RNA, mRNA to 40S ribosome, ribosomal subunits. In addition these prot ... * Silvestrol ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Vietnam
Vietnam, officially the Socialist Republic of Vietnam (SRV), is a country at the eastern edge of mainland Southeast Asia, with an area of about and a population of over 100 million, making it the world's List of countries and dependencies by population, fifteenth-most populous country. One of two communist states in Southeast Asia, Vietnam shares land borders with China to the north, and Laos and Cambodia to the west. It shares Maritime boundary, maritime borders with Thailand through the Gulf of Thailand, and the Philippines, Indonesia, and Malaysia through the South China Sea. Its capital is Hanoi and its largest city is Ho Chi Minh City. Vietnam was inhabited by the Paleolithic age, with states established in the first millennium BC on the Red River Delta in modern-day northern Vietnam. Before the Han dynasty's invasion, Vietnam was marked by a vibrant mix of religion, culture, and social norms. The Han dynasty annexed Northern and Central Vietnam, which were subs ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Solomon Islands
Solomon Islands, also known simply as the Solomons,John Prados, ''Islands of Destiny'', Dutton Caliber, 2012, p,20 and passim is an island country consisting of six major islands and over 1000 smaller islands in Melanesia, part of Oceania, to the northeast of Australia. It is directly adjacent to Autonomous Region of Bougainville, Bougainville, a part of Papua New Guinea to the west, Australia to the southwest, New Caledonia and Vanuatu to the southeast, Fiji, Wallis and Futuna, and Tuvalu to the east, and Nauru and the Federated States of Micronesia to the north. It has a total area of 28,896 square kilometres (11,157 sq mi), and a population of 734,887 according to the official estimates for mid-2023. Its capital and largest city, Honiara, is located on the largest island, Guadalcanal. The country takes its name from the wider area of the Solomon Islands (archipelago), Solomon Islands archipelago, which is a collection of Melanesian islands that also includes the Autonomous ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Plant
Plants are the eukaryotes that form the Kingdom (biology), kingdom Plantae; they are predominantly Photosynthesis, photosynthetic. This means that they obtain their energy from sunlight, using chloroplasts derived from endosymbiosis with cyanobacteria to produce sugars from carbon dioxide and water, using the green pigment chlorophyll. Exceptions are parasitic plants that have lost the genes for chlorophyll and photosynthesis, and obtain their energy from other plants or fungi. Most plants are multicellular organism, multicellular, except for some green algae. Historically, as in Aristotle's biology, the plant kingdom encompassed all living things that were not animals, and included algae and fungi. Definitions have narrowed since then; current definitions exclude fungi and some of the algae. By the definition used in this article, plants form the clade Viridiplantae (green plants), which consists of the green algae and the embryophytes or land plants (hornworts, liverworts ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Philippines
The Philippines, officially the Republic of the Philippines, is an Archipelagic state, archipelagic country in Southeast Asia. Located in the western Pacific Ocean, it consists of List of islands of the Philippines, 7,641 islands, with a total area of roughly 300,000 square kilometers, which are broadly categorized in Island groups of the Philippines, three main geographical divisions from north to south: Luzon, Visayas, and Mindanao. With a population of over 110 million, it is the world's List of countries and dependencies by population, twelfth-most-populous country. The Philippines is bounded by the South China Sea to the west, the Philippine Sea to the east, and the Celebes Sea to the south. It shares maritime borders with Taiwan to the north, Japan to the northeast, Palau to the east and southeast, Indonesia to the south, Malaysia to the southwest, Vietnam to the west, and China to the northwest. It has Ethnic groups in the Philippines, diverse ethnicities and Culture o ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Papua New Guinea
Papua New Guinea, officially the Independent State of Papua New Guinea, is an island country in Oceania that comprises the eastern half of the island of New Guinea and offshore islands in Melanesia, a region of the southwestern Pacific Ocean north of Australia. It has Indonesia–Papua New Guinea border, a land border with Indonesia to the west and neighbours Australia to the south and the Solomon Islands to the east. Its capital, on its southern coast, is Port Moresby. The country is the world's third largest list of island countries, island country, with an area of . The nation was split in the 1880s between German New Guinea in the North and the Territory of Papua, British Territory of Papua in the South, the latter of which was ceded to Australia in 1902. All of present-day Papua New Guinea came under Australian control following World War I, with the legally distinct Territory of New Guinea being established out of the former German colony as a League of Nations mandate. T ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |