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African Meningitis Belt
The African meningitis belt is a region in sub-Saharan Africa where the rate of incidence of meningitis is very high. It extends from Senegal to Ethiopia, and the primary cause of meningitis in the belt is ''Neisseria meningitidis''. The belt was first proposed by Léon Lapeyssonnie of the World Health Organization (WHO) in 1963. Lapeyssonnie noticed that the disease occurred in areas receiving 300–1,100 mm of mean annual rainfall, which is the case in sub-Saharan Africa. The intercontinental spread of meningitis has also been traced to South Asia, brought by those making the Hajj, a pilgrimage to Saudi Arabia, in 1987, leading to epidemics in Nepal, Saudi Arabia, and Chad. Regions It consists of part of or all of (from West to East), the Gambia, Senegal, Guinea-Bissau, Guinea, Mali, Burkina Faso, Ghana, Niger, Nigeria, Cameroon, Chad, Central African Republic, Sudan, South Sudan, Uganda, Kenya, Ethiopia, Eritrea. Many other countries in Africa experience outbreaks as well, ...
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Meningococcal Meningitis Range
''Neisseria meningitidis'', often referred to as the meningococcus, is a Gram-negative bacterium that can cause meningitis and other forms of meningococcal disease such as meningococcemia, a life-threatening sepsis. The bacterium is referred to as a coccus because it is round, and more specifically a diplococcus because of its tendency to form pairs. About 10% of adults are carriers of the bacteria in their nasopharynx. As an exclusively human pathogen, it causes developmental impairment and death in about 10% of cases. It causes the only form of bacterial meningitis known to occur epidemically, mainly in Africa and Asia. It occurs worldwide in both epidemic and endemic form. ''N. meningitidis'' is spread through saliva and respiratory secretions during coughing, sneezing, kissing, chewing on toys and through sharing a source of fresh water. It has also been reported to be transmitted through oral sex and cause urethritis in men. It infects its host cells by sticking to them wit ...
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Ghana
Ghana, officially the Republic of Ghana, is a country in West Africa. It is situated along the Gulf of Guinea and the Atlantic Ocean to the south, and shares borders with Côte d’Ivoire to the west, Burkina Faso to the north, and Togo to the east. Ghana covers an area of , spanning diverse ecologies, from coastal savannas to tropical rainforests. With nearly 35 million inhabitants, Ghana is the second-most populous country in West Africa. The capital and largest city is Accra; other significant cities include Tema, Kumasi, Sunyani, Ho, Cape Coast, Techiman, Tamale, and Sekondi-Takoradi. The earliest kingdoms to emerge in Ghana were Bonoman in the south and the Kingdom of Dagbon in the north, with Bonoman existing in the area during the 11th century. The  Asante Empire and other Akan kingdoms in the south emerged over the centuries. Beginning in the 15th century, the Portuguese Empire, followed by other European powers, contested the area for trading r ...
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Serotype
A serotype or serovar is a distinct variation within a species of bacteria or virus or among immune cells of different individuals. These microorganisms, viruses, or Cell (biology), cells are classified together based on their shared reactivity between their surface antigens and a particular antiserum, allowing the classification of organisms to a Infraspecific name, level below the species. A group of serovars with common antigens is called a serogroup or sometimes ''serocomplex''. Serotyping often plays an essential role in determining species and subspecies. The ''Salmonella'' genus of bacteria, for example, has been determined to have over 2600 serotypes. ''Vibrio cholerae'', the species of bacteria that causes cholera, has over 200 serotypes, based on cell antigens. Only two of them have been observed to produce the potent enterotoxin that results in cholera: O1 and O139. Serotypes were discovered in hemolytic streptococci by the American microbiologist Rebecca Lancefield i ...
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United States
The United States of America (USA), also known as the United States (U.S.) or America, is a country primarily located in North America. It is a federal republic of 50 U.S. state, states and a federal capital district, Washington, D.C. The 48 contiguous states border Canada to the north and Mexico to the south, with the semi-exclave of Alaska in the northwest and the archipelago of Hawaii in the Pacific Ocean. The United States asserts sovereignty over five Territories of the United States, major island territories and United States Minor Outlying Islands, various uninhabited islands in Oceania and the Caribbean. It is a megadiverse country, with the world's List of countries and dependencies by area, third-largest land area and List of countries and dependencies by population, third-largest population, exceeding 340 million. Its three Metropolitan statistical areas by population, largest metropolitan areas are New York metropolitan area, New York, Greater Los Angeles, Los Angel ...
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Attack Rate
In epidemiology, the attack rate is the proportion of an at-risk population that contracts the disease during a specified time interval. It is used in hypothetical predictions and during actual outbreaks of disease. An at-risk population is defined as one that has no immunity to the attacking pathogen, which can be either a novel pathogen or an established pathogen. It is used to project the number of infections to expect during an epidemic. This aids in marshalling resources for delivery of medical care as well as production of vaccines and/or anti-viral and anti-bacterial medicines. The rate is arrived at by taking the number of new cases in the population at risk and dividing by the number of persons at risk in the population. See also * Incidence (epidemiology) In epidemiology Epidemiology is the study and analysis of the distribution (who, when, and where), patterns and Risk factor (epidemiology), determinants of health and disease conditions in a defined populat ...
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Malaria
Malaria is a Mosquito-borne disease, mosquito-borne infectious disease that affects vertebrates and ''Anopheles'' mosquitoes. Human malaria causes Signs and symptoms, symptoms that typically include fever, Fatigue (medical), fatigue, vomiting, and headaches. In severe cases, it can cause jaundice, Epileptic seizure, seizures, coma, or death. Symptoms usually begin 10 to 15 days after being bitten by an infected ''Anopheles'' mosquito. If not properly treated, people may have recurrences of the disease months later. In those who have recently survived an infection, reinfection usually causes milder symptoms. This partial Immunity (medical), resistance disappears over months to years if the person has no continuing exposure to malaria. The mosquitoes themselves are harmed by malaria, causing reduced lifespans in those infected by it. Malaria is caused by protozoa, single-celled microorganisms of the genus ''Plasmodium''. It is spread exclusively through bites of infected female ...
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Eritrea
Eritrea, officially the State of Eritrea, is a country in the Horn of Africa region of East Africa, with its capital and largest city being Asmara. It is bordered by Ethiopia in the Eritrea–Ethiopia border, south, Sudan in the west, and Djibouti in the southeast. The northeastern and eastern parts of Eritrea have an extensive coastline along the Red Sea. The nation has a total area of approximately , and includes the Dahlak Archipelago and several of the Hanish Islands. Hominid remains found in Eritrea have been dated to 1 million years old and anthropological research indicates that the area may contain significant records related to the evolution of humans. The Kingdom of Aksum, covering much of modern-day Eritrea and Tigray Region, northern Ethiopia, was established during the first or second century AD.Henze, Paul B. (2005) ''Layers of Time: A History of Ethiopia'', . It adopted Eritrean Orthodox Church, Christianity around the middle of the fourth century. Beginning in ...
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Kenya
Kenya, officially the Republic of Kenya, is a country located in East Africa. With an estimated population of more than 52.4 million as of mid-2024, Kenya is the 27th-most-populous country in the world and the 7th most populous in Africa. Kenya's capital and largest city is Nairobi. Its second-largest and oldest city is Mombasa, a major port city located on Mombasa Island. Other major cities within the country include Kisumu, Nakuru & Eldoret. Going clockwise, Kenya is bordered by South Sudan to the northwest (though much of that border includes the disputed Ilemi Triangle), Ethiopia to the north, Somalia to the east, the Indian Ocean to the southeast, Tanzania to the southwest, and Lake Victoria and Uganda to the west. Kenya's geography, climate and population vary widely. In western, rift valley counties, the landscape includes cold, snow-capped mountaintops (such as Batian, Nelion and Point Lenana on Mount Kenya) with vast surrounding forests, wildlife and ...
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Uganda
Uganda, officially the Republic of Uganda, is a landlocked country in East Africa. It is bordered to the east by Kenya, to the north by South Sudan, to the west by the Democratic Republic of the Congo, to the south-west by Rwanda, and to the south by Tanzania. The southern part includes a substantial portion of Lake Victoria, shared with Kenya and Tanzania. Uganda is in the African Great Lakes region, lies within the Nile basin, and has a varied equatorial climate. , it has a population of 49.3 million, of whom 8.5 million live in the capital and largest city, Kampala. Uganda is named after the Buganda, Buganda kingdom, which encompasses a large portion of the south, including Kampala, and whose language Luganda is widely spoken; the official language is English. The region was populated by various ethnic groups, before Bantu and Nilotic groups arrived around 3,000 years ago. These groups established influential kingdoms such as the Empire of Kitara. The arrival of Arab trade ...
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South Sudan
South Sudan (), officially the Republic of South Sudan, is a landlocked country in East Africa. It is bordered on the north by Sudan; on the east by Ethiopia; on the south by the Democratic Republic of the Congo, Uganda and Kenya; and on the west by the Central African Republic. South Sudan's diverse landscape includes vast plains and plateaus, dry and tropical savannahs, inland floodplains, and forested mountains. The Nile, Nile River system is the defining physical feature of the country, running south to north across its center, which is dominated by a large swamp known as the Sudd. South Sudan has a population of just over 12.7 million in 2024. Juba is the Capital city, capital and largest city. Sudan was occupied by History of Egypt under the Muhammad Ali dynasty, Egypt under the Muhammad Ali dynasty and governed as an Anglo-Egyptian Sudan, Anglo-Egyptian condominium until Sudanese independence in 1956. Following the First Sudanese Civil War, the Southern Sudan Autonomous ...
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Sudan
Sudan, officially the Republic of the Sudan, is a country in Northeast Africa. It borders the Central African Republic to the southwest, Chad to the west, Libya to the northwest, Egypt to the north, the Red Sea to the east, Eritrea and Ethiopia to the southeast, and South Sudan to the south. Sudan has a population of 50 million people as of 2024 and occupies 1,886,068 square kilometres (728,215 square miles), making it Africa's List of African countries by area, third-largest country by area and the third-largest by area in the Arab League. It was the largest country by area in Africa and the Arab League until the 2011 South Sudanese independence referendum, secession of South Sudan in 2011; since then both titles have been held by Algeria. Sudan's capital and most populous city is Khartoum. The area that is now Sudan witnessed the Khormusan ( 40000–16000 BC), Halfan culture ( 20500–17000 BC), Sebilian ( 13000–10000 BC), Qadan culture ( 15000–5000 BC), the war of Jebel ...
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Central African Republic
The Central African Republic (CAR) is a landlocked country in Central Africa. It is bordered by Chad to Central African Republic–Chad border, the north, Sudan to Central African Republic–Sudan border, the northeast, South Sudan to Central African Republic–South Sudan border, the east, the Democratic Republic of the Congo to Central African Republic–Democratic Republic of the Congo border, the south, the Republic of the Congo to Central African Republic–Republic of the Congo border, the southwest, and Cameroon to Cameroon–Central African Republic border, the west. Bangui is the country's capital and largest city, bordering the Democratic Republic of the Congo. The Central African Republic covers a land area of about . As of 2024, it has a population of 5,357,744, consisting of about 80 ethnic groups, and is in the scene of a Central African Republic Civil War, civil war, which has been ongoing since 2012. Having been a Ubangi-Shari, French colony under the name Ubangi ...
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