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A Brief History Of Everyone Who Ever Lived
''A Brief History of Everyone Who Ever Lived: The Stories in Our Genes'' (published in the United States as ''A Brief History of Everyone Who Ever Lived: The Human Story Retold Through Our Genes'') is a popular science book by British geneticist, author and broadcaster Adam Rutherford. It was first published in 2016 in the United Kingdom by Weidenfeld & Nicolson. An updated edition was published in the United States in 2017, with a different subtitle, by The Experiment. The book is about human genetics and what it reveals about human identity and their history. ''A Brief History of Everyone Who Ever Lived'' won gold at the 2017 Foreword INDIE Book Awards for Science, and won the 2018 Thomas Bonner Book Prize. The book was also a 2017 National Book Critics Circle Award non-fiction finalist, featured on the 2017 Wellcome Book Prize longlist, and appeared on National Geographic's top 12 books from 2017. Table of contents *Foreword by Siddhartha Mukherjee /sup> *Introduction *Par ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Adam Rutherford
Adam David Rutherford (born January 1975) is a British geneticist and science populariser. He was an audio-visual content editor for the journal ''Nature'' for a decade, and is a frequent contributor to the newspaper ''The Guardian''. He formerly hosted the BBC Radio 4 programmes '' Inside Science'' and (with Hannah Fry) ''The Curious Cases of Rutherford and Fry''; has produced several science documentaries; and has published books related to genetics and the origin of life. He is an honorary senior research associate in the division of biosciences at University College London. Rutherford became President of Humanists UK in June 2022, succeeding Alice Roberts. Early life and education Rutherford, who is half- Guyanese Indian, was born in Ipswich in the East of England and attended Ipswich School. He was admitted to the medical school at University College London, but transferred to a degree in evolutionary genetics, including a project under Steve Jones studying stalk- ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Genomes
A genome is all the genetic information of an organism. It consists of nucleotide sequences of DNA (or RNA in RNA viruses). The nuclear genome includes protein-coding genes and non-coding genes, other functional regions of the genome such as regulatory sequences (see non-coding DNA), and often a substantial fraction of junk DNA with no evident function. Almost all eukaryotes have mitochondria and a small mitochondrial genome. Algae and plants also contain chloroplasts with a chloroplast genome. The study of the genome is called genomics. The genomes of many organisms have been sequenced and various regions have been annotated. The first genome to be sequenced was that of the virus φX174 in 1977; the first genome sequence of a prokaryote (''Haemophilus influenzae'') was published in 1995; the yeast (''Saccharomyces cerevisiae'') genome was the first eukaryotic genome to be sequenced in 1996. The Human Genome Project was started in October 1990, and the first draft sequence ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Panacea (medicine)
A panacea () is any supposed remedy that is claimed (for example) to cure all diseases and prolong life indefinitely. Named after the Greek goddess of universal remedy Panacea, it was in the past sought by alchemists in connection with the elixir of life and the philosopher's stone, a mythical substance that would enable the transmutation of common metals into gold. Through the 18th and 19th centuries, many "patent medicines" were claimed to be panaceas, and they became very big business. The term "panacea" is used in a negative way to describe the overuse of any one solution to solve many different problems, especially in medicine. The word has acquired connotations of snake oil and quackery. A panacea (or ''panaceum'') is also a literary term to represent any solution to solve all problems related to a particular issue. Mythology In Greek mythology, Panacea was one of the daughters of the Greek god of medicine Asclepius, along with her four sisters, each of whom performed ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Human Genome Project
The Human Genome Project (HGP) was an international scientific research project with the goal of determining the base pairs that make up human DNA, and of identifying, mapping and sequencing all of the genes of the human genome from both a physical and a functional standpoint. It started in 1990 and was completed in 2003. It was the world's largest collaborative biological project. Planning for the project began in 1984 by the US government, and it officially launched in 1990. It was declared complete on 14 April 2003, and included about 92% of the genome. Level "complete genome" was achieved in May 2021, with only 0.3% of the bases covered by potential issues. The final gapless assembly was finished in January 2022. Funding came from the US government through the National Institutes of Health (NIH) as well as numerous other groups from around the world. A parallel project was conducted outside the government by the Celera Corporation, or Celera Genomics, which was formall ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Eugenics
Eugenics is a set of largely discredited beliefs and practices that aim to improve the genetic quality of a human population. Historically, eugenicists have attempted to alter the frequency of various human phenotypes by inhibiting the fertility of those considered inferior, or promoting that of those considered superior. The contemporary history of eugenics began in the late 19th century, when a popular eugenics movement emerged in the United Kingdom, and then spread to many countries, including the United States, Canada, Australia, and most European countries (e.g. Sweden and Germany). In this period, people from across the political spectrum espoused eugenics. Many countries adopted eugenic policies intended to improve the quality of their populations. Historically, the idea of ''eugenics'' has been used to argue for a broad array of practices ranging from prenatal care for mothers deemed genetically desirable to the forced sterilization and murder of those deemed unf ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Francis Galton
Sir Francis Galton (; 16 February 1822 – 17 January 1911) was an English polymath and the originator of eugenics during the Victorian era; his ideas later became the basis of behavioural genetics. Galton produced over 340 papers and books. He also developed the statistical concept of correlation and widely promoted regression toward the mean. He was the first to apply statistical methods to the study of human differences and inheritance of intelligence, and introduced the use of questionnaires and Statistical survey, surveys for collecting data on human communities, which he needed for genealogical and biographical works and for his anthropometrics, anthropometric studies. He popularised the phrase "nature versus nurture". His book ''Hereditary Genius'' (1869) was the first social scientific attempt to study genius and greatness. As an investigator of the human mind, he founded psychometrics and differential psychology, as well as the lexical hypothesis of personality. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lactase Persistence
Lactase persistence or lactose tolerance is the continued activity of the lactase enzyme in adulthood, allowing the digestion of lactose in milk. In most mammals, the activity of the enzyme is dramatically reduced after weaning. In some human populations though, lactase persistence has recently evolved as an adaptation to the consumption of nonhuman milk and dairy products beyond infancy. Lactase persistence is very high among northern Europeans. Worldwide, most people are lactase ''non''-persistent, and are affected by varying degrees of lactose intolerance as adults. However, lactase persistence and lactose intolerance can overlap. Global distribution of the phenotype The distribution of the lactase persistence (LP) phenotype, or the ability to digest lactose into adulthood, is not homogeneous in the world. Lactase persistence frequencies are highly variable. In Europe, the distribution of the lactase persistence phenotype is clinal, with frequencies ranging from 15–54% in ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lactose Intolerance
Lactose intolerance is caused by a lessened ability or a complete inability to digest lactose, a sugar found in dairy products. Humans vary in the amount of lactose they can tolerate before symptoms develop. Symptoms may include abdominal pain, bloating, diarrhea, flatulence, and nausea. These symptoms typically start thirty minutes to two hours after eating or drinking something containing lactose, with the severity typically depending on the amount consumed. Lactose intolerance does not cause damage to the gastrointestinal tract. Lactose intolerance is due to the lack of the enzyme lactase in the small intestines to break lactose down into glucose and galactose. There are four types: primary, secondary, developmental, and congenital. Primary lactose intolerance occurs as the amount of lactase declines as people grow up. Secondary lactose intolerance is due to injury to the small intestine. Such injury could be the result of infection, celiac disease, inflammatory bowel disea ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Earwax
Earwax, also known by the medical term cerumen, is a waxy substance secreted in the ear canal of humans and other mammals. Earwax can be many colors, including brown, orange, red, yellowish, and gray. Earwax protects the skin of the human ear canal, assists in cleaning and lubrication, and provides protection against bacteria, fungi, particulate matter, and water. Major components of earwax include cerumen, produced by a type of modified sweat gland, and sebum, an oily substance. Both components are made by glands located in the outer ear canal. The chemical composition of earwax includes saturated and unsaturated long chain fatty acids, alcohols, squalene, and cholesterol. Earwax also contains dead skin cells and hair. Excess or compacted cerumen is the buildup of ear wax causing a blockage in the ear canal and it can press against the eardrum or block the outside ear canal or hearing aids, potentially causing hearing loss. Physiology Cerumen is produced in the ca ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Red Hair
Red hair, also known as ginger hair, is a human hair color found in 2–6% of people of northern Europe, Northern or Northwestern European ancestry and lesser frequency in other populations. It is most common in individuals Zygosity#Homozygous, homozygous for a Dominance (genetics), recessive allele on chromosome 16 that produces an altered version of the melanocortin 1 receptor, MC1R protein. Red hair varies in hue from a deep Burgundy (color), burgundy or bright Copper (color), copper, or auburn hair, auburn, to burnt orange or red-orange to Venetian blonde, strawberry blond. Characterized by high levels of the reddish pigment pheomelanin and relatively low levels of the dark pigment eumelanin, it is typically associated with Light skin, fair skin color, lighter eye color, freckles, and sensitivity to ultraviolet light. Cultural reactions to red hair have been varied. The term "redhead" has been in use since at least 1510, while the term "ginger" is sometimes used, espec ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Incest
Incest ( ) is sexual intercourse, sex between kinship, close relatives, for example a brother, sister, or parent. This typically includes sexual activity between people in consanguinity (blood relations), and sometimes those related by lineage (anthropology), lineage. It is condemned and considered immoral in many societies. It can lead to an increased risk of genetic disorders in children in case of pregnancy from incestuous sex. The incest taboo is one of the most widespread of all cultural taboos, both in present and in past societies. Most modern societies have laws regarding incest or social restrictions on closely consanguineous marriages. In societies where it is illegal, consensual adult incest is seen by some as a victimless crime. Some cultures extend the incest taboo to relatives with no consanguinity, such as Milk kinship, milk-siblings, stepsiblings, and adoptive siblings, albeit sometimes with less intensity. Third-degree relatives (such as half-aunt, half-nephew ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Charles II Of Spain
Charles II (6 November 1661 – 1 November 1700) was King of Spain from 1665 to 1700. The last monarch from the House of Habsburg, which had ruled Spain since 1516, he died without an heir, leading to a European Great Power conflict over the succession. For reasons still debated, Charles experienced lengthy periods of ill health throughout his life. This made the question of who would succeed him central to European diplomacy for much of his reign, one historian writing that "from the day of his birth, they were waiting for his death". The two main candidates were the Austrian Habsburg Archduke Charles, and 16-year-old Philip of Anjou, grandson of Charles' half-sister Maria Theresa and Louis XIV of France. Shortly before his death in November 1700, Charles named Philip his heir, but the acquisition of an undivided Spanish Empire by either France or Austria threatened the European balance of power. Failure to resolve these issues through diplomacy resulted in the 1701 to ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
