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AP2 (other)
AP2 or ''variant'', may refer to: Biochemistry * Activating protein 2 (AP-2), a mammalian transcription factor * Adipocyte protein 2 (aP2), a carrier protein for fatty acids * AP2 adaptors (AP-2 complex), which aid clathrin mediated endocytosis * Apetala 2 (AP2), a plant transcription factor Vehicles and transportation * Automotive products AP2, Automatic transmission used in the minimatic, mini, metro, allegro and 1100/1300 road vehicles. * Autopista AP-2, a roadway in Spain * Seversky AP-2, a U.S. interwar patrol fighter plane * , a U.S. Navy WWII transport ship * Honda S2000 AP2, a variant of the Honda S2000 automobile Other uses * Amiga Power, the follow-up website to Amiga gaming magazine * Argyle Park, industrial/experimental band See also * Automotive Products, a manufacturer of automatic transmissions in UK * AP (other) * APP (other) * APAP (other) * 2AP (other) * * * {{Letter-NumberCombDisambig ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Activating Protein 2
Activating Protein 2 (AP-2) is a family of closely related transcription factor In molecular biology, a transcription factor (TF) (or sequence-specific DNA-binding factor) is a protein that controls the rate of transcription (genetics), transcription of genetics, genetic information from DNA to messenger RNA, by binding t ...s which plays a critical role in regulating gene expression during early development. References External links * Gene expression Transcription factors {{gene-20-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Adipocyte Protein 2
aP2 (adipocyte Protein 2) is a carrier protein for fatty acids that is primarily expressed in adipocytes and macrophages. aP2 is also called fatty acid binding protein 4 (FABP4). Blocking this protein either through genetic engineering or drugs has the possibility of treating heart disease and the metabolic syndrome. See also * Fatty acid-binding protein The fatty-acid-binding proteins (FABPs) are a family of transport proteins for fatty acids and other lipophilic substances such as eicosanoids and retinoids. These proteins are thought to facilitate the transfer of fatty acids between extra- and i ... References External links * * PDBe-KBprovides an overview of all the structure information available in the PDB for Human Fatty acid-binding protein, adipocyte PDBe-KBprovides an overview of all the structure information available in the PDB for Mouse Fatty acid-binding protein, adipocyte Proteins {{gene-8-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
AP2 Adaptors
The AP2 adaptor complex is a multimeric protein that works on the cell membrane to internalize cargo in clathrin-mediated endocytosis. It is a stable complex of four adaptins which give rise to a structure that has a core domain and two appendage domains attached to the core domain by polypeptide linkers. These appendage domains are sometimes called 'ears'. The core domain binds to the membrane and to cargo destined for internalisation. The alpha and beta appendage domains bind to accessory proteins and to clathrin. Their interactions allow the temporal and spatial regulation of the assembly of clathrin-coated vesicles and their endocytosis. The AP-2 complex is a heterotetramer consisting of two large adaptins (α and β), a medium adaptin (μ), and a small adaptin (σ): * complex 2 ** AP2A1 (α unit 1) ** AP2A2 (α unit 2) ** AP2B1 (β unit) ** AP2M1 (μ unit) ** AP2S1 (σ unit) Structure The AP2 adaptor complex exists in two primary conformations: the open conformation ( ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Apetala 2
Apetala 2 (AP2) is a gene and a member of a large family of transcription factors, the AP2/ EREBP family. In ''Arabidopsis thaliana'' AP2 plays a role in the ABC model of flower development. It was originally thought that this family of proteins was plant-specific; however, recent studies have shown that apicomplexans, including the causative agent of malaria, ''Plasmodium falciparum'' encode a related set of transcription factors, called the ApiAP2 family. In the ''A. thaliana'' transcription factor RAV1 the N-terminal AP2 domain binds 5'-CAACA -3' sequence, while the C-terminal highly conserved B3 domain The B3 DNA binding domain (DBD) is a highly conserved domain found exclusively in transcription factors (≥40 species) () combined with other domains (). It consists of 100-120 residues, includes seven beta strands and two alpha helices that fo ... binds 5'-CACCTG -3' sequence. Structure and Biological Content of AP2 Through recent studies, Apetala 2 is found to hav ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Autopista AP-2
The Autopista AP-2 also known as the Autopista del Nordeste (North-East motorway), is a highway ( autopista) in the north of Spain that connects the northern coast with the eastern coast of the country. It starts at the city of Zaragoza, passes Lleida and ends at El Vendrell, 70 kilometers west of Barcelona, where it connects with AP-7. It was a toll road, and forms part of the European route E90. Route It is a major motorway in Spain because it is between Barcelona and Madrid. The free state-owned A-2 autovía is available between Madrid and Zaragoza, and between Lleida and Barcelona, but from Zaragoza to Lleida the traffic needs to either transfer to AP-2 or continue to Zaragoza through the standard highway N-II. It was finished at 1977 and was exploited under a concession agreement operated by Abertis Abertis Infraestructuras, S.A. () is a Spanish worldwide corporation engaged in toll road management. The company is headquartered in Madrid. The company runs over 8,600 kil ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Seversky AP-2
The Seversky P-35 is an American fighter aircraft built by the Seversky Aircraft Company in the late 1930s. A contemporary of the Hawker Hurricane and Messerschmitt Bf 109, the P-35 was the first single-seat fighter in United States Army Air Corps to feature all-metal construction, retractable landing gear, and an enclosed cockpit. Design and development The origins of the P-35 can be traced back to the Seversky SEV-3 three-seat amphibian, designed by Alexander Kartveli, Seversky's chief designer and Seversky's first aircraft. The SEV-3 first flew in June 1933 and was developed into the Seversky BT-8 basic trainer, 30 of which were ordered by the United States Army Air Corps (USAAC) in 1935.Green and Swanborough 1979, pp. 8–9. This proved grossly underpowered and was quickly replaced by the North American BT-9.Davies 1994, p. 4. The second prototype SEV-3 was completed as a two-seat fighter derivative, the SEV-2XP. It was powered by a 735 hp (548 kW) Wright R-1820 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
