ALVAC-CEA Vaccine
ALVAC-CEA vaccine is a cancer vaccine containing a canary pox virus (ALVAC) combined with the carcinoembryonic antigen Carcinoembryonic antigen (CEA) describes a set of highly related glycoproteins involved in cell adhesion. CEA is normally produced in gastrointestinal tissue during fetal development, but the production stops before birth. Consequently, CEA is ... (CEA) human gene. A phase I trial in 118 patients showed safety in humans. References External links ALVAC-CEA vaccineentry in the public domain NCI Dictionary of Cancer Terms Cancer vaccines {{vaccine-stub ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Cancer Vaccine
A cancer vaccine is a vaccine that either treats existing cancer or prevents development of cancer. Vaccines that treat existing cancer are known as ''therapeutic'' cancer vaccines or tumor antigen vaccines. Some of the vaccines are "autologous", being prepared from samples taken from the patient, and are specific to that patient. Some researchers claim that cancerous cells routinely arise and are destroyed by the immune system ( immunosurveillance); and that tumors form when the immune system fails to destroy them. Some types of cancer, such as cervical cancer and liver cancer, are caused by viruses ( oncoviruses). Traditional vaccines against those viruses, such as the HPV vaccine and the hepatitis B vaccine, prevent those types of cancer. Other cancers are to some extent caused by bacterial infections (e.g. stomach cancer and ''Helicobacter pylori''). Traditional vaccines against cancer-causing bacteria ( oncobacteria) are not further discussed in this article. Method One ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Canary Pox Virus
Canarypox virus (CNPV) is an ''Avipoxvirus'' and etiologic agent of canarypox, a disease of wild and captive birds that can cause significant losses. Canarypox can enter human cells, but it cannot survive and multiply in human cells. There is a live viral vaccine available which may have beneficial properties against human cancer when used as a mammalian expression vector. (ATCvet code: ). Furthermore, the POXIMUNE® C vaccine does offer direct protection against CNPV in susceptible birds. Generally CNPV is considered a disease of songbirds, such as canaries, magpies and nightingales, and is associated with higher mortality rates when compared to other avian pox viruses. In some instances, mortality approaches 100%. Avian pox viruses also cause significant economic losses in domestic poultry and remain a problem in the conservation of endemic bird species inhabiting islands. The general symptoms of CNPV are similar to those of other species of avian pox viruses and are charac ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Carcinoembryonic Antigen
Carcinoembryonic antigen (CEA) describes a set of highly related glycoproteins involved in cell adhesion. CEA is normally produced in gastrointestinal tissue during fetal development, but the production stops before birth. Consequently, CEA is usually present at very low levels in the blood of healthy adults (about 2–4 ng/mL). However, the serum levels are raised in some types of cancer, which means that it can be used as a tumor marker in clinical tests. Serum levels can also be elevated in heavy smokers. CEA are glycosyl phosphatidyl inositol (GPI) cell-surface-anchored glycoproteins whose specialized sialo fucosylated glycoforms serve as functional colon carcinoma L-selectin and E-selectin ligands, which may be critical to the metastatic dissemination of colon carcinoma cells. Immunologically they are characterized as members of the CD66 cluster of differentiation. The proteins include CD66a, CD66b, CD66c, CD66d, CD66e, CD66f. History CEA was first identifi ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Human Gene
This article is an index of lists of human genes. By chromosome Below is a list of articles on human chromosomes, each of which contains an incomplete list of genes located on that chromosome. * Chromosome 1 (human) * Chromosome 2 (human) * Chromosome 3 (human) * Chromosome 4 (human) * Chromosome 5 (human) * Chromosome 6 (human) * Chromosome 7 (human) * Chromosome 8 (human) * Chromosome 9 (human) * Chromosome 10 (human) * Chromosome 11 (human) * Chromosome 12 (human) * Chromosome 13 (human) * Chromosome 14 (human) * Chromosome 15 (human) * Chromosome 16 (human) * Chromosome 17 (human) * Chromosome 18 (human) * Chromosome 19 (human) * Chromosome 20 (human) * Chromosome 21 (human) * Chromosome 22 (human) * Chromosome X (human) * Chromosome Y (human) Protein-coding genes The lists below constitute a complete list of all known human protein-coding genes. Transcription factors This is a list of 1639 genes which encode proteins that are known or expected to function as human transc ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |