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AICD
The acronym AICD may refer to: *Automated Implantable Cardioverter-Defibrillator *Amyloid precursor protein Intracellular Cytoplasmic/C-terminal Domain, the smaller cleavage product of APP by gamma-secretase *Australian Institute of Company Directors The Australian Institute of Company Directors (AICD) is a non-profit membership organization for directors. The AICD is a founding member of the Global Network of Director Institutes (GNDI). History The origins of the AICD can be traced ba ..., an organisation supporting company directors in Australia * Activation-induced cell death (AICD), important for maintaining T cell homeostasis of the immune system. Autoreactive T cells undergo apoptosis through AICD both from the thymus and periphery {{disambig ...
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Australian Institute Of Company Directors
The Australian Institute of Company Directors (AICD) is a non-profit membership organization for directors. The AICD is a founding member of the Global Network of Director Institutes (GNDI). History The origins of the AICD can be traced back to the United Kingdom's Institute of Directors (IoD), formed by royal charter in 1906. Branches of the IoD appeared in the Australian states in the 1960s. These branches were amalgamated in January 1971 under the Institute of Directors in Australia, an autonomous body affiliated with the IoD in the United Kingdom. The challenge of servicing state branches saw the emergence of the Company Directors Association of Australia in 1982. The two bodies merged on 1 January 1990 to form the Australian Institute of Company Directors. In 2022, an AICD seminar on cybersecurity was crashed by hackers. International associations AICD is a founding member of the Global Director Development Circle, now known as the Global Network of Directors Instit ...
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Implantable Cardioverter-defibrillator
An implantable cardioverter-defibrillator (ICD) or automated implantable cardioverter defibrillator (AICD) is a device implantable inside the body, able to perform defibrillation, and depending on the type, cardioversion and pacing of the heart. The ICD is the first-line treatment and prophylactic therapy for patients at risk for sudden cardiac death due to ventricular fibrillation and ventricular tachycardia. "AICD" was trademarked by the Boston Scientific corporation, so the more generic "ICD" is preferred terminology. On average ICD batteries last about six to ten years. Advances in technology, such as batteries with more capacity or rechargeable batteries, may allow batteries to last for more than ten years. The leads (electrical cable wires connecting the device to the heart) have much longer average longevity, but can malfunction in various ways, specifically insulation failure or fracture of the conductor; thus, ICDs and leads generally require replacement after ...
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Amyloid Precursor Protein
Amyloid-beta precursor protein (APP) is an integral membrane protein expressed in many biological tissue, tissues and concentrated in the synapses of neurons. It functions as a cell surface receptor and has been implicated as a regulator of synapse formation, neural plasticity, antimicrobial activity, and iron export. It is coded for by the gene ''APP'' and regulated by substrate presentation. APP is best known as the precursor molecule whose proteolysis generates amyloid beta (Aβ), a polypeptide containing 37 to 49 amino acid residues, whose Amyloid#Structure, amyloid fibrillar form is the primary component of amyloid plaques found in the brains of Alzheimer's disease patients. Genetics Amyloid-beta precursor protein is an ancient and highly Conserved sequence, conserved protein. In humans, the gene ''APP'' is located on chromosome 21 and contains 18 exons spanning 290 kilobases. Several alternative splicing isoforms of APP have been observed in humans, ranging in length ...
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