2023 Nobel Prize In Physiology Or Medicine
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2023 Nobel Prize In Physiology Or Medicine
The 2023 Nobel Prize in Physiology or Medicine was awarded to Katalin Karikó (born 1955) and Drew Weissman (born 1959) "for their discoveries concerning nucleoside base modifications that enabled the development of effective mRNA vaccines against COVID-19". Laureates Katalin Karikó Katalin Karikó was born on January 17, 1955, in Szolnok, Hungary. From the University of Szeged, she received a Ph.D. in biochemistry in 1982. From 2013 to 2022, she was associated with BioNTech RNA Pharmaceuticals, first as a vice president and promoted to senior vice president in 2019. This company, a division of BioNTech, commercialized mRNA vaccines at a global scale. Drew Weissman Drew Weissman was born on September 7, 1959, in Lexington, Massachusetts and received a Ph.D. in 1987 at Boston University. He started studying RNA at the University of Pennsylvania in 1997, where he met Karikó. Key publications The following publications were the fundamental researches that motivated the ...
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Nobel Prize Medal
The Nobel Prize medal is a gold medal given to recipients of the Nobel Prizes of Nobel Prize in Chemistry, Chemistry, Nobel Prize in Literature, Literature, Nobel Peace Prize, Peace, Nobel Prize in Physics, Physics and Nobel Prize in Physiology or Medicine, Physiology or Medicine since 1901. The medal for the Nobel Memorial Prize in Economic Sciences, given since 1968, is awarded with the aforementioned prizes. Each medal has a portrait of Alfred Nobel in left profile on the obverse and reverse, obverse. The medals for chemistry, literature, physics, and physiology or medicine have an identical portrait of Nobel with different portraits on the peace and economics prize medals. The medals for chemistry, literature, physics, and physiology or medicine were designed by Erik Lindberg. The peace prize medal was designed by Gustav Vigeland, and the economics prize medal by Gunvor Svensson-Lundqvist. The medals are struck in 18 carat coloured gold#Green gold, green gold plated with 24 ca ...
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MRNA Vaccine
An mRNA vaccine is a type of vaccine that uses a copy of a molecule called messenger RNA (mRNA) to produce an immune response. The vaccine delivers molecules of antigen-encoding mRNA into cells, which use the designed mRNA as a blueprint to build foreign protein that would normally be produced by a pathogen (such as a virus) or by a cancer cell. These protein molecules stimulate an adaptive immune response that teaches the body to identify and destroy the corresponding pathogen or cancer cells. The mRNA is delivered by a co-formulation of the RNA encapsulated in lipid nanoparticles that protect the RNA strands and help their absorption into the cells. Reactogenicity, the tendency of a vaccine to produce adverse reactions, is similar to that of conventional non-RNA vaccines. People susceptible to an autoimmune response may have an adverse reaction to messenger RNA vaccines. The advantages of mRNA vaccines over traditional vaccines are ease of design, speed and lower cost ...
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University Of Pennsylvania
The University of Pennsylvania (Penn or UPenn) is a Private university, private Ivy League research university in Philadelphia, Pennsylvania, United States. One of nine colonial colleges, it was chartered in 1755 through the efforts of founder and first president Benjamin Franklin, who had advocated for an educational institution that trained leaders in academia, commerce, and public service. The university has four undergraduate schools and 12 graduate and professional schools. Schools enrolling undergraduates include the College of Arts and Sciences, the University of Pennsylvania School of Engineering and Applied Science, School of Engineering and Applied Science, the Wharton School, and the University of Pennsylvania School of Nursing, School of Nursing. Among its graduate schools are its University of Pennsylvania Law School, law school, whose first professor, James Wilson (Founding Father), James Wilson, helped write the Constitution of the United States, U.S. Cons ...
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Boston University
Boston University (BU) is a Private university, private research university in Boston, Massachusetts, United States. BU was founded in 1839 by a group of Boston Methodism, Methodists with its original campus in Newbury (town), Vermont, Newbury, Vermont. It was chartered in Boston in 1869. The university is a member of the Association of American Universities and the Boston Consortium for Higher Education. The university has nearly 38,000 students and more than 4,000 faculty members and is one of Boston's largest employers. It offers bachelor's degrees, master's degrees, doctorates, and medical, dental, business, and law degrees through 17 schools and colleges on three urban campuses. The university is nonsectarian, though it retains its historical affiliation with the United Methodist Church. The main campus is situated along the Charles River in Boston's Fenway–Kenmore and Allston, Massachusetts, Allston neighborhoods, while the Boston University Medical Campus is locate ...
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Lexington, Massachusetts
Lexington is a suburban town in Middlesex County, Massachusetts, United States, located 10 miles (16 km) from Downtown Boston. The population was 34,454 as of the 2020 United States census, 2020 census. The area was originally inhabited by Native Americans, and was first settled by Europeans as a farming community. Lexington is well known as the site of the first shots of the American Revolutionary War, in the Battles of Lexington and Concord, Battle of Lexington on April 19, 1775, where the "Shot heard round the world, Shot heard 'round the world" took place. It is home to Minute Man National Historical Park. History Indigenous history Native Americans in the United States, Native Americans inhabited the area that would become Lexington for thousands of years prior to European colonization of the Americas, as attested by a woodland era archaeological site near Loring Hill south of the town center. At the time of European contact, the area may have been a border region ...
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BioNTech
BioNTech SE ( ; or short for Biopharmaceutical New Technologies) is a German multinational biotechnology company headquartered in Mainz that develops immunotherapies and vaccines, particularly for cancer and infectious diseases. The company utilizes technology platforms including mRNA-based therapies, targeted therapies, and immunomodulators, to develop its treatments. BioNTech's pipeline includes several late-stage programs in oncology testing combination therapy approaches to improve treatment outcomes. In the field of infectious diseases, BioNTech, partnering with Pfizer, developed Comirnaty, the first approved mRNA-based vaccine, which was widely used during the COVID-19 pandemic. History Foundation (2008–2014) BioNTech was founded in 2008 based on research by Uğur Şahin, Özlem Türeci, and Christoph Huber, with a seed investment of €180 million from MIG Capital, a Munich-based venture capital firm, the family office of Andreas and Thomas Strüngmann, ...
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Doctor Of Philosophy
A Doctor of Philosophy (PhD, DPhil; or ) is a terminal degree that usually denotes the highest level of academic achievement in a given discipline and is awarded following a course of Postgraduate education, graduate study and original research. The name of the degree is most often abbreviated PhD (or, at times, as Ph.D. in North American English, North America), pronounced as three separate letters ( ). The University of Oxford uses the alternative abbreviation "DPhil". PhDs are awarded for programs across the whole breadth of academic fields. Since it is an earned research degree, those studying for a PhD are required to produce original research that expands the boundaries of knowledge, normally in the form of a Thesis, dissertation, and, in some cases, defend their work before a panel of other experts in the field. In many fields, the completion of a PhD is typically required for employment as a university professor, researcher, or scientist. Definition In the context o ...
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University Of Szeged
The University of Szeged () is a Public university, public research university in Szeged, Hungary. Established as the Jesuit Academy of Kolozsvár in present-day Cluj-Napoca in 1581, the institution was re-established as a university in 1872 by Emperor Franz Joseph I of Austria, Franz Joseph I. The university relocated to Szeged in 1921, making it one of the oldest research universities in Hungary. It went through numerous changes throughout the 20th century and was eventually divided into distinct independent universities. The current University of Szeged was formed in 2000 and is made up of twelve constituent Faculty (division), faculties and nineteen doctoral schools, which consist of a range of departments and research groups. Each faculty functions autonomously. In addition to these, the university also operates the Health Centre of the University of Szeged, an extensive teaching hospital responsible for Public healthcare, public regional Health care, healthcare, and three l ...
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Szolnok
Szolnok (; also known by #Name and etymology, alternative names) is the county seat of Jász-Nagykun-Szolnok county in central Hungary. A city with county rights, it is located on the banks of the Tisza river, in the heart of the Great Hungarian Plain, which has made it an important cultural and economic crossroads for centuries. Szolnok also has one of Hungary’s best water polo teams. Name and etymology Szolnok was named after the first steward of the city, Szolnok (ispán), Szaunik or Zounok. The town was first officially mentioned under the name Zounok in 1075. In the following centuries, it was recorded variously as Zounok, Saunic, Zounuc, and Zawnuch. The variety of spellings likely comes from phonetic discrepancies occurring when Hungarian sounds were recorded using the Latin alphabet. Another possibility revolves around speculation that the name Szaunik was not a personal name after all, but rather a title relating to the significant salt trade (salt, ) in the area. In m ...
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COVID-19
Coronavirus disease 2019 (COVID-19) is a contagious disease caused by the coronavirus SARS-CoV-2. In January 2020, the disease spread worldwide, resulting in the COVID-19 pandemic. The symptoms of COVID‑19 can vary but often include fever, fatigue, cough, breathing difficulties, anosmia, loss of smell, and ageusia, loss of taste. Symptoms may begin one to fourteen days incubation period, after exposure to the virus. At least a third of people who are infected asymptomatic, do not develop noticeable symptoms. Of those who develop symptoms noticeable enough to be classified as patients, most (81%) develop mild to moderate symptoms (up to mild pneumonia), while 14% develop severe symptoms (dyspnea, hypoxia (medical), hypoxia, or more than 50% lung involvement on imaging), and 5% develop critical symptoms (respiratory failure, shock (circulatory), shock, or organ dysfunction, multiorgan dysfunction). Older people have a higher risk of developing severe symptoms. Some complicati ...
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2024 Nobel Prize In Physiology Or Medicine
The 2024 Nobel Prize in Physiology or Medicine was awarded jointly to Victor Ambros and Gary Ruvkun "for the discovery of microRNA and its role in post-transcriptional gene regulation"The Nobel Prize in Physiology or Medicine 2024
nobelprize.org secretary of the in , Sweden, on 7 October 2024.


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Nobel Assembly At Karolinska Institutet
The Nobel Assembly at the Karolinska Institute is a body at Karolinska Institute that awards the Nobel Prize in Physiology or Medicine. It is headquartered in the Nobel Forum on the grounds of the Karolinska Institute campus. Originally the Nobel Assembly was not a formal body but rather the collective of all professors (holders of chairs, i.e. full professors) at Karolinska Institute. In 1977, the Nobel Assembly became a separate private organization hosted by Karolinska Institute. Until 1984, all Karolinska Institute professors belonged to the Assembly; since 1984, the membership has been restricted to 50 Karolinska Institute professors.Karolinska Institutet: ''Nobelpriset - den ärofyllda traditionen''
accessed on August 3, 2009
The main work involved in collecting nominations and sc ...
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