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2-ethylhexyl Salicylate
2-Ethylhexyl salicylate also known as octisalate or octyl salicylate, is an organic compound used as an ingredient in sunscreens and cosmetics to absorb UVB (ultraviolet) rays from the sun. It is an ester formed by the condensation of salicylic acid with 2-Ethylhexanol, 2-ethylhexanol. It is a colorless oily liquid with a slight floral odor. The salicylate portion of the molecule absorbs ultraviolet light, protecting skin from the harmful effects of exposure to sunlight. The ethylhexanol portion is a fatty alcohol, adding emollient and oil-like (water resistant) properties. Safety According to the classification provided by companies to ECHA in Registration, Evaluation, Authorisation and Restriction of Chemicals, REACH registrations this substance is very toxic to aquatic life with long lasting effects and is suspected of damaging the unborn child. In 2020 the ECHA decided that a fish sexual development test of the chemical was necessary, because the compound may be an endocrin ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Organic Compound
Some chemical authorities define an organic compound as a chemical compound that contains a carbon–hydrogen or carbon–carbon bond; others consider an organic compound to be any chemical compound that contains carbon. For example, carbon-containing compounds such as alkanes (e.g. methane ) and its derivatives are universally considered organic, but many others are sometimes considered inorganic, such as certain compounds of carbon with nitrogen and oxygen (e.g. cyanide ion , hydrogen cyanide , chloroformic acid , carbon dioxide , and carbonate ion ). Due to carbon's ability to catenate (form chains with other carbon atoms), millions of organic compounds are known. The study of the properties, reactions, and syntheses of organic compounds comprise the discipline known as organic chemistry. For historical reasons, a few classes of carbon-containing compounds (e.g., carbonate salts and cyanide salts), along with a few other exceptions (e.g., carbon dioxide, and even ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Registration, Evaluation, Authorisation And Restriction Of Chemicals
Registration, Evaluation, Authorisation and Restriction of Chemicals (REACH) is a European Union regulation dating from 18 December 2006, amended on 16 December 2008 by Regulation (EC) No 1272/2008. REACH addresses the production and use of chemical substances, and their potential impacts on both human health and the environment. Its 849 pages took seven years to pass, and it has been described as the most complex legislation in the Union's history and the most important in 20 years. It is the strictest law to date regulating chemical substances and will affect industries throughout the world. REACH entered into force on 1 June 2007, with a phased implementation over the next decade. The regulation also established the European Chemicals Agency, which manages the technical, scientific and administrative aspects of REACH. Overview When REACH is fully in force, it will require all companies manufacturing or importing chemical substances into the European Union in quantities of o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Salicylate Esters
Salicylic acid is an organic compound with the formula HOC6H4COOH. A colorless (or white), bitter-tasting solid, it is a precursor to and a metabolite of acetylsalicylic acid (aspirin). It is a plant hormone, and has been listed by the EPA Toxic Substances Control Act (TSCA) Chemical Substance Inventory as an experimental teratogen. The name is from Latin for willow tree, from which it was initially identified and derived. It is an ingredient in some anti-acne products. Salts and esters of salicylic acid are known as salicylates. Uses Medicine Salicylic acid as a medication is commonly used to remove the outermost layer of the skin. As such, it is used to treat warts, psoriasis, acne vulgaris, ringworm, dandruff, and ichthyosis. Similar to other hydroxy acids, salicylic acid is an ingredient in many skincare products for the treatment of seborrhoeic dermatitis, acne, psoriasis, calluses, corns, keratosis pilaris, acanthosis nigricans, ichthyosis, and warts. Uses in ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Avobenzone
Avobenzone (trade names Parsol 1789, Milestab 1789, Eusolex 9020, Escalol 517, Neo Heliopan 357 and others, International Nomenclature of Cosmetic Ingredients, INCI Butyl Methoxydibenzoylmethane) is an organic molecule and an oil-soluble ingredient used in sunscreen products to absorb the full spectrum of Ultraviolet, UVA rays. History Avobenzone was patented in 1973 and was approved in the EU in 1978. It was approved by the Food and Drug Administration, FDA in 1988. As of 2021, the FDA announced that they do not support avobenzone as being generally recognized as safe and effective (GRASE) citing the need for additional safety data. Avobenzone was banned in 2020 by the Palau government citing reef-toxicity concerns. Properties Pure avobenzone is a whitish to yellowish crystalline powder with a weak odor, dissolving in isopropanol, dimethyl sulfoxide, decyl oleate, capric acid/caprylic, triglycerides and other oils. It is not soluble in water. Avobenzone is a dibenzoylmethane ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Oxybenzone
Oxybenzone or benzophenone-3 or BP-3 (trade names Milestab 9, Eusolex 4360, Escalol 567, KAHSCREEN BZ-3) is an organic compound belonging to the class of aromatic ketones known as benzophenones. It takes the form of pale-yellow crystals that are readily soluble in most organic solvents. It is widely used in sunscreen formulations, plastics, toys, furniture finishes, and other products to limit UV degradation. In nature, it can be found in various flowering plants (angiosperms). The compound was first synthesised in Germany by chemists König and Kostanecki in 1906. The use of oxybenzone as sunscreen ingredient is currently under scrutiny by the scientific community due to controversies about the molecule's environmental impact and safety profile (see section below). As a result, sunscreens containing oxybenzone have been banned from sale in Hawaii, Palau, and Thailand. Structure and electronic structure Being a conjugated molecule, oxybenzone absorbs light at lower energies ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
2-ethylhexyl Salicylate
2-Ethylhexyl salicylate also known as octisalate or octyl salicylate, is an organic compound used as an ingredient in sunscreens and cosmetics to absorb UVB (ultraviolet) rays from the sun. It is an ester formed by the condensation of salicylic acid with 2-Ethylhexanol, 2-ethylhexanol. It is a colorless oily liquid with a slight floral odor. The salicylate portion of the molecule absorbs ultraviolet light, protecting skin from the harmful effects of exposure to sunlight. The ethylhexanol portion is a fatty alcohol, adding emollient and oil-like (water resistant) properties. Safety According to the classification provided by companies to ECHA in Registration, Evaluation, Authorisation and Restriction of Chemicals, REACH registrations this substance is very toxic to aquatic life with long lasting effects and is suspected of damaging the unborn child. In 2020 the ECHA decided that a fish sexual development test of the chemical was necessary, because the compound may be an endocrin ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Homosalate
Homosalate is an organic compound used in some sunscreens. It is made by the Fischer–Speier esterification of salicylic acid and 3,3,5-trimethylcyclohexanol, the latter being a hydrogenated derivative of isophorone. Contained in 45% of U.S. sunscreens, it is used as a chemical UV filter. The salicylic acid portion of the molecule absorbs ultraviolet rays with a wavelength from 295 nm to 315 nm, protecting the skin from sun damage. The hydrophobic trimethyl cyclohexyl group provides greasiness that prevents it from dissolving in water. Safety Homosalate was identified in a court case brought by German chemical company Symrise who claimed that the ingredient used in sunscreen did not require animal testing. Symrise lost the appeal against a European Chemicals Agency (ECHA) decision that requires the German manufacturer to test sunscreen ingredients on animals. The Court of Justice of the European Union (CJEU) decision applies to two formerly approved ingredients use ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Symrise
Symrise AG is a German chemicals company that is a major producer of flavours and fragrances with sales of €4.999 billion i2024 Major competitors include Givaudan, Takasago International Corporation, International Flavors and Fragrances and Döhler. Symrise is a member of the European Flavour Association. In 2021, Symrise was ranked 4th by FoodTalks' Global Top 50 Food Flavours and Fragrances Companies list. History Symrise was founded in 2003 by the merger of Bayer subsidiary Haarmann & Reimer (H&R) and Dragoco, both based in Holzminden, Germany. Haarman & Reimer Haarman & Reimer (H&R) was founded in 1874 by chemists Ferdinand Tiemann and Wilhelm Haarmann after they succeeded in first synthesizing vanillin from coniferin. Holzminden was the site where vanillin was first produced industrially. In 1917, H&R supported Leopold Ružička's unsuccessful three-year project to synthesize irone, a fragrance of violets. In 1953, H&R was acquired by Bayer. Dragoco Dragoco was ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Endocrine Disruptor
Endocrine disruptors, sometimes also referred to as hormonally active agents, endocrine disrupting chemicals, or endocrine disrupting compounds are chemicals that can interfere with endocrine (or hormonal) systems. These disruptions can cause numerous adverse human health outcomes, including alterations in sperm quality and fertility; abnormalities in sex organs‚ endometriosis‚ early puberty‚ altered nervous system or immune function; certain cancers; respiratory problems; metabolic issues; diabetes, obesity, or cardiovascular problems; growth, neurological and learning disabilities, and more. Found in many household and industrial products, endocrine disruptors "interfere with the synthesis, secretion, transport, binding, action, or elimination of natural hormones in the body that are responsible for development, behavior, fertility, and maintenance of homeostasis (normal cell metabolism)." Any system in the body controlled by hormones can be derailed by hormone disrupt ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
ECHA
The European Chemicals Agency (ECHA; ) is an agency of the European Union working for the safe use of chemicals. It manages the technical and administrative aspects of the implementation of the European Union regulation called Registration, Evaluation, Authorisation and Restriction of Chemicals (REACH). ECHA is the driving force among regulatory authorities in implementing the EU's chemicals legislation. ECHA has to ascertain that companies comply with the legislation, advances the safe use of chemicals, provides information on chemicals and addresses chemicals of concern. It is located in Helsinki, Finland and is operational since 2007. ECHA is an independent and mature regulatory agency established by REACH. It is not a subsidiary entity of the European Commission. The agency is headed by Executive Director Sharon McGuinness. Establishment The ECHA was created by European Union regulation dating from 18 December 2006 to manage the then-new legislation to regulate the man ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sunscreen
Sunscreen, also known as sunblock, sun lotion or sun cream, is a photoprotection, photoprotective topical product for the Human skin, skin that helps protect against sunburn and prevent skin cancer. Sunscreens come as lotions, sprays, gels, foams (such as an expanded foam lotion or whipped lotion), sticks, powders and other topical products. Sunscreens are common supplements to clothing, particularly sunglasses, sunhats and special sun protective clothing, and other forms of photoprotection (such as umbrellas). Sunscreens may be classified according to the type of #Active_ingredients, active ingredient(s) present in the formulation (inorganic compounds or organic compound, organic molecules) as: * Mineral sunscreens (also referred to as physical), which use only inorganic compounds (zinc oxide and/or titanium dioxide) as active ingredients. These ingredients primarily work by absorbing UV rays but also through reflection and refraction. * Chemical sunscreens, which use organic ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Emollient
A moisturizer, or emollient, is a cosmetic preparation used for protecting, moisturizing, and lubricating the skin. These functions are normally performed by sebum produced by healthy skin. The word "emollient" is derived from the Latin verb ''mollire'', to soften. Mechanism of action In the human body, water constantly evaporates from the deeper layers of the skin through an effect known as transepidermal water loss. By regulating its water content, human skin naturally maintains a dry, easily shed surface as a barrier against pathogens, dirt, or damage, while protecting itself from drying out and becoming brittle and rigid. The ability to retain moisture depends on the lipid bilayer between the dead skin cells. Moisturizers modify the rate of water loss, with active ingredients of moisturizers falling into one of two categories: occlusives and humectants. ''Occlusives'' form a hydrophobic coating on the surface of the skin, keeping moisture from escaping. The more occl ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
