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A calutron is a
mass spectrometer Mass spectrometry (MS) is an analytical technique that is used to measure the mass-to-charge ratio of ions. The results are presented as a '' mass spectrum'', a plot of intensity as a function of the mass-to-charge ratio. Mass spectrometry is us ...
originally designed and used for separating the isotopes of
uranium Uranium is a chemical element with the symbol U and atomic number 92. It is a silvery-grey metal in the actinide series of the periodic table. A uranium atom has 92 protons and 92 electrons, of which 6 are valence electrons. Uranium is weak ...
. It was developed by
Ernest Lawrence Ernest Orlando Lawrence (August 8, 1901 – August 27, 1958) was an American nuclear physicist and winner of the Nobel Prize in Physics in 1939 for his invention of the cyclotron. He is known for his work on uranium-isotope separation fo ...
during the
Manhattan Project The Manhattan Project was a research and development undertaking during World War II that produced the first nuclear weapons. It was led by the United States with the support of the United Kingdom and Canada. From 1942 to 1946, the project w ...
and was based on his earlier invention, the
cyclotron A cyclotron is a type of particle accelerator invented by Ernest O. Lawrence in 1929–1930 at the University of California, Berkeley, and patented in 1932. Lawrence, Ernest O. ''Method and apparatus for the acceleration of ions'', filed: Jan ...
. Its name was derived from California University Cyclotron, in tribute to Lawrence's institution, the
University of California The University of California (UC) is a public land-grant research university system in the U.S. state of California. The system is composed of the campuses at Berkeley, Davis, Irvine, Los Angeles, Merced, Riverside, San Diego, San Franci ...
, where it was invented. Calutrons were used in the industrial-scale Y-12
uranium enrichment Enriched uranium is a type of uranium in which the percent composition of uranium-235 (written 235U) has been increased through the process of isotope separation. Naturally occurring uranium is composed of three major isotopes: uranium-238 (238 ...
plant at the
Clinton Engineer Works The Clinton Engineer Works (CEW) was the production installation of the Manhattan Project that during World War II produced the enriched uranium used in the 1945 bombing of Hiroshima, as well as the first examples of reactor-produced pluton ...
in Oak Ridge, Tennessee. The
enriched uranium Enriched uranium is a type of uranium in which the percent composition of uranium-235 (written 235U) has been increased through the process of isotope separation. Naturally occurring uranium is composed of three major isotopes: uranium-238 (238U ...
produced was used in the
Little Boy "Little Boy" was the type of atomic bomb dropped on the Japanese city of Hiroshima on 6 August 1945 during World War II, making it the first nuclear weapon used in warfare. The bomb was dropped by the Boeing B-29 Superfortress ''Enola Gay'' p ...
atomic bomb that was detonated over Hiroshima on 6 August 1945. The calutron is a type of
sector mass spectrometer A sector instrument is a general term for a class of mass spectrometer that uses a static electric (E) or magnetic (B) sector or some combination of the two (separately in space) as a mass analyzer. Popular combinations of these sectors have been ...
, an instrument in which a sample is
ionized Ionization, or Ionisation is the process by which an atom or a molecule acquires a negative or positive charge by gaining or losing electrons, often in conjunction with other chemical changes. The resulting electrically charged atom or molecule ...
and then accelerated by electric fields and deflected by magnetic fields. The ions ultimately collide with a plate and produce a measurable electric current. Since the ions of the different isotopes have the same electric charge but different masses, the heavier isotopes are deflected less by the magnetic field, causing the beam of particles to separate into several beams by mass, striking the plate at different locations. The
mass Mass is an intrinsic property of a body. It was traditionally believed to be related to the quantity of matter in a physical body, until the discovery of the atom and particle physics. It was found that different atoms and different eleme ...
of the ions can be calculated according to the strength of the field and the charge of the ions. During World War II, calutrons were developed to use this principle to obtain substantial quantities of high-purity uranium-235, by taking advantage of the small mass difference between uranium isotopes. Electromagnetic separation for uranium enrichment was abandoned in the post-war period in favor of the more complicated, but more efficient,
gaseous diffusion Gaseous diffusion is a technology used to produce enriched uranium by forcing gaseous uranium hexafluoride (UF6) through semipermeable membranes. This produces a slight separation between the molecules containing uranium-235 (235U) and uranium-2 ...
method. Although most of the calutrons of the Manhattan Project were dismantled at the end of the war, some remained in use to produce isotopically enriched samples of naturally occurring elements for military, scientific and medical purposes.


Origins

News of the discovery of nuclear fission by German chemists
Otto Hahn Otto Hahn (; 8 March 1879 – 28 July 1968) was a German chemist who was a pioneer in the fields of radioactivity and radiochemistry. He is referred to as the father of nuclear chemistry and father of nuclear fission. Hahn and Lise Meitner ...
and
Fritz Strassmann Friedrich Wilhelm Strassmann (; 22 February 1902 – 22 April 1980) was a German chemist who, with Otto Hahn in December 1938, identified the element barium as a product of the bombardment of uranium with neutrons. Their observation was the ke ...
in 1938, and its theoretical explanation by Lise Meitner and Otto Frisch, was brought to the United States by
Niels Bohr Niels Henrik David Bohr (; 7 October 1885 – 18 November 1962) was a Danish physicist who made foundational contributions to understanding atomic structure and quantum theory, for which he received the Nobel Prize in Physics in 1922 ...
. Based on his
liquid drop model In nuclear physics, the semi-empirical mass formula (SEMF) (sometimes also called the Weizsäcker formula, Bethe–Weizsäcker formula, or Bethe–Weizsäcker mass formula to distinguish it from the Bethe–Weizsäcker process) is used to approxi ...
of the nucleus, he theorized that it was the
uranium-235 Uranium-235 (235U or U-235) is an isotope of uranium making up about 0.72% of natural uranium. Unlike the predominant isotope uranium-238, it is fissile, i.e., it can sustain a nuclear chain reaction. It is the only fissile isotope that exi ...
isotope and not the more abundant uranium-238 that was primarily responsible for fission with
thermal neutron The neutron detection temperature, also called the neutron energy, indicates a free neutron's kinetic energy, usually given in electron volts. The term ''temperature'' is used, since hot, thermal and cold neutrons are moderated in a medium wi ...
s. To verify this Alfred O. C. Nier at the
University of Minnesota The University of Minnesota, formally the University of Minnesota, Twin Cities, (UMN Twin Cities, the U of M, or Minnesota) is a public land-grant research university in the Twin Cities of Minneapolis and Saint Paul, Minnesota, United States. ...
used a
mass spectrometer Mass spectrometry (MS) is an analytical technique that is used to measure the mass-to-charge ratio of ions. The results are presented as a '' mass spectrum'', a plot of intensity as a function of the mass-to-charge ratio. Mass spectrometry is us ...
to create a microscopic amount of enriched uranium-235 in April 1940. John R. Dunning,
Aristid von Grosse Aristid von Grosse (January 1905 – July 21, 1985) was a German nuclear chemist. During his work with Otto Hahn, he got access to waste material from radium production, and with this starting material he was able in 1927 to isolate protact ...
and Eugene T. Booth were then able to confirm that Bohr was correct.
Leo Szilard Leo Szilard (; hu, Szilárd Leó, pronounced ; born Leó Spitz; February 11, 1898 – May 30, 1964) was a Hungarian-German-American physicist and inventor. He conceived the nuclear chain reaction in 1933, patented the idea of a nuclear ...
and Walter Zinn soon confirmed that more than one neutron was released per fission, which made it almost certain that a nuclear chain reaction could be initiated, and therefore that the development of an atomic bomb was a theoretical possibility. There were fears that a German atomic bomb project would develop one first, especially among scientists who were refugees from
Nazi Germany Nazi Germany (lit. "National Socialist State"), ' (lit. "Nazi State") for short; also ' (lit. "National Socialist Germany") (officially known as the German Reich from 1933 until 1943, and the Greater German Reich from 1943 to 1945) was ...
and other fascist countries. At the
University of Birmingham The University of Birmingham (informally Birmingham University) is a Public university, public research university located in Edgbaston, Birmingham, United Kingdom. It received its royal charter in 1900 as a successor to Queen's College, Birmingha ...
in Britain, the Australian physicist
Mark Oliphant Sir Marcus Laurence Elwin Oliphant, (8 October 1901 – 14 July 2000) was an Australian physicist and humanitarian who played an important role in the first experimental demonstration of nuclear fusion and in the development of nuclear weapon ...
assigned two refugee physicists—Otto Frisch and
Rudolf Peierls Sir Rudolf Ernst Peierls, (; ; 5 June 1907 – 19 September 1995) was a German-born British physicist who played a major role in Tube Alloys, Britain's nuclear weapon programme, as well as the subsequent Manhattan Project, the combined Allie ...
—the task of investigating the feasibility of an atomic bomb, ironically because their status as enemy aliens precluded their working on secret projects like
radar Radar is a detection system that uses radio waves to determine the distance ('' ranging''), angle, and radial velocity of objects relative to the site. It can be used to detect aircraft, ships, spacecraft, guided missiles, motor vehicles, we ...
. Their March 1940 Frisch–Peierls memorandum indicated that the
critical mass In nuclear engineering, a critical mass is the smallest amount of fissile material needed for a sustained nuclear chain reaction. The critical mass of a fissionable material depends upon its nuclear properties (specifically, its nuclear fi ...
of uranium-235 was within an
order of magnitude An order of magnitude is an approximation of the logarithm of a value relative to some contextually understood reference value, usually 10, interpreted as the base of the logarithm and the representative of values of magnitude one. Logarithmic di ...
of 10 kg, which was small enough to be carried by a
bomber A bomber is a military combat aircraft designed to attack ground and naval targets by dropping air-to-ground weaponry (such as bombs), launching torpedoes, or deploying air-launched cruise missiles. The first use of bombs dropped from an air ...
of the day. The British
Maud Committee The MAUD Committee was a British scientific working group formed during the Second World War. It was established to perform the research required to determine if an atomic bomb was feasible. The name MAUD came from a strange line in a telegram fro ...
then unanimously recommended pursuing the development of an atomic bomb. Britain had offered to give the United States access to its scientific research, so the
Tizard Mission The Tizard Mission, officially the British Technical and Scientific Mission, was a British delegation that visited the United States during WWII to obtain the industrial resources to exploit the military potential of the research and development ( ...
's
John Cockcroft Sir John Douglas Cockcroft, (27 May 1897 – 18 September 1967) was a British physicist who shared with Ernest Walton the Nobel Prize in Physics in 1951 for splitting the atomic nucleus, and was instrumental in the development of nuclea ...
briefed American scientists on British developments. He discovered that the American project was smaller than the British, and not as far advanced. A disappointed Oliphant flew to the United States to speak to the American scientists. These included
Ernest Lawrence Ernest Orlando Lawrence (August 8, 1901 – August 27, 1958) was an American nuclear physicist and winner of the Nobel Prize in Physics in 1939 for his invention of the cyclotron. He is known for his work on uranium-isotope separation fo ...
at the
University of California The University of California (UC) is a public land-grant research university system in the U.S. state of California. The system is composed of the campuses at Berkeley, Davis, Irvine, Los Angeles, Merced, Riverside, San Diego, San Franci ...
's
Radiation Laboratory The Radiation Laboratory, commonly called the Rad Lab, was a microwave and radar research laboratory located at the Massachusetts Institute of Technology (MIT) in Cambridge, Massachusetts. It was first created in October 1940 and operated until 31 ...
in
Berkeley Berkeley most often refers to: *Berkeley, California, a city in the United States **University of California, Berkeley, a public university in Berkeley, California * George Berkeley (1685–1753), Anglo-Irish philosopher Berkeley may also refer ...
. The two men had met before the war, and were friends. Lawrence was sufficiently impressed to commence his own research into uranium. Uranium-235 makes up only about 0.72% of natural uranium, so the separation factor of any uranium enrichment process needs to be higher than 1250 to produce 90% uranium-235 from natural uranium. The Maud Committee had recommended that this be done by a process of
gaseous diffusion Gaseous diffusion is a technology used to produce enriched uranium by forcing gaseous uranium hexafluoride (UF6) through semipermeable membranes. This produces a slight separation between the molecules containing uranium-235 (235U) and uranium-2 ...
, but Oliphant had pioneered another technique in 1934: electromagnetic separation. This was the process that Nier had used. The principle of electromagnetic separation is that charged
ion An ion () is an atom or molecule with a net electrical charge. The charge of an electron is considered to be negative by convention and this charge is equal and opposite to the charge of a proton, which is considered to be positive by conve ...
s are deflected by a magnetic field, and lighter ones are deflected more than heavy ones. The reason the Maud Committee, and later its American counterpart, the S-1 Section of the
Office of Scientific Research and Development The Office of Scientific Research and Development (OSRD) was an agency of the United States federal government created to coordinate scientific research for military purposes during World War II. Arrangements were made for its creation during May 1 ...
(OSRD), had passed over the electromagnetic method was that while the mass spectrometer was capable of separating isotopes, it produced very low yields. The reason for this was the so-called
space charge Space charge is an interpretation of a collection of electric charges in which excess electric charge is treated as a continuum of charge distributed over a region of space (either a volume or an area) rather than distinct point-like charges. Thi ...
limitation. Positive ions have positive charge, so they tend to repel each other, which causes the beam to scatter. Drawing on his experience with the precise control of charged-particle beams from his work with his invention, the
cyclotron A cyclotron is a type of particle accelerator invented by Ernest O. Lawrence in 1929–1930 at the University of California, Berkeley, and patented in 1932. Lawrence, Ernest O. ''Method and apparatus for the acceleration of ions'', filed: Jan ...
, Lawrence suspected that the air molecules in the vacuum chamber would neutralize the ions, and create a focused beam. Oliphant inspired Lawrence to convert his old cyclotron into a giant mass spectrometer for
isotope separation Isotope separation is the process of concentrating specific isotopes of a chemical element by removing other isotopes. The use of the nuclides produced is varied. The largest variety is used in research (e.g. in chemistry where atoms of "marker" n ...
. The 37-inch cyclotron at Berkeley was dismantled on 24 November 1941, and its magnet used to create the first calutron. Its name came from ''Cal''ifornia ''U''niversity and cyclo''tron''. The work was initially funded by the Radiation Laboratory from its own resources, with a $5,000 grant from the Research Corporation. In December Lawrence received a $400,000 grant from the S-1 Uranium Committee. The calutron consisted of an ion source, in the form of a box with a slit in it and hot filaments inside.
Uranium tetrachloride Uranium tetrachloride is an inorganic compound, a salt of uranium and chlorine, with the formula UCl4. It is a hygroscopic olive-green solid. It was used in the electromagnetic isotope separation (EMIS) process of uranium enrichment. It is one o ...
was ionized by the filament, and then passed through a slot into a vacuum chamber. The magnet was then used to deflect the ion beam by 180°. The enriched and depleted beams went into collectors. When the calutron was first operated on 2 December 1941, just days before the
Japanese attack on Pearl Harbor The attack on Pearl HarborAlso known as the Battle of Pearl Harbor was a surprise military strike by the Imperial Japanese Navy Air Service upon the United States against the naval base at Pearl Harbor in Honolulu, Territory of Hawaii, ju ...
brought the United States into
World War II World War II or the Second World War, often abbreviated as WWII or WW2, was a world war that lasted from 1939 to 1945. It involved the vast majority of the world's countries—including all of the great powers—forming two opposing ...
, a uranium beam intensity of 5 microamperes (μA) was received by the collector. Lawrence's hunch about the effect of the air molecules in the vacuum chamber was confirmed. A nine-hour run on 14 January 1942 with a 50 μA beam produced 18 micrograms (μg) of uranium enriched to 25% uranium-235, about ten times as much as Nier had produced. By February, improvements in the technique allowed it to generate a 1,400 μA beam. That month, 75 μg samples enriched to 30% were shipped to the British and the Metallurgical Laboratory in Chicago. Other researchers also investigated electromagnetic isotope separation. At
Princeton University Princeton University is a private research university in Princeton, New Jersey. Founded in 1746 in Elizabeth as the College of New Jersey, Princeton is the fourth-oldest institution of higher education in the United States and one of the ...
, a group led by Henry D. Smyth and
Robert R. Wilson Robert Rathbun Wilson (March 4, 1914 – January 16, 2000) was an American physicist known for his work on the Manhattan Project during World War II, as a sculptor, and as an architect of the Fermi National Accelerator Laboratory (Fermilab), ...
developed a device known as an isotron. Using a
klystron A klystron is a specialized linear-beam vacuum tube, invented in 1937 by American electrical engineers Russell and Sigurd Varian,Pond, Norman H. "The Tube Guys". Russ Cochran, 2008 p.31-40 which is used as an amplifier for high radio frequen ...
, they were able to separate isotopes using high-voltage electricity rather than magnetism. Work continued until February 1943, when, in view of the greater success of the calutron, work was discontinued and the team was transferred to other duties. At
Cornell University Cornell University is a private statutory land-grant research university based in Ithaca, New York. It is a member of the Ivy League. Founded in 1865 by Ezra Cornell and Andrew Dickson White, Cornell was founded with the intention to tea ...
a group under Lloyd P. Smith that included William E. Parkins, and A. Theodore Forrester devised a radial magnetic separator. They were surprised that their beams were more precise than expected, and, like Lawrence, deduced that it was a result of stabilization of the beam by air in the vacuum chamber. In February 1942, their team was consolidated with Lawrence's in Berkeley.


Research

While the process had been demonstrated to work, considerable effort was still required before a prototype could be tested in the field. Lawrence assembled a team of physicists to tackle the problems, including
David Bohm David Joseph Bohm (; 20 December 1917 – 27 October 1992) was an American-Brazilian-British scientist who has been described as one of the most significant theoretical physicists of the 20th centuryPeat 1997, pp. 316-317 and who contributed ...
,
Edward Condon Edward Uhler Condon (March 2, 1902 – March 26, 1974) was an American nuclear physicist, a pioneer in quantum mechanics, and a participant during World War II in the development of radar and, very briefly, of nuclear weapons as part of the ...
,
Donald Cooksey Donald Cooksey (May 15, 1892 – August 19, 1977), was an American physicist who was associate director of the Lawrence Radiation Laboratory of the University of California at Berkeley. Cooksey was the son of George Cooksey from Birmingham, Engla ...
, A. Theodore Forrester, Irving Langmuir,
Kenneth Ross MacKenzie Kenneth Ross MacKenzie (June 15, 1912 – July 4, 2002) together with Dale R. Corson and Emilio Segrè, synthesized the element astatine, in 1940. MacKenzie received his PhD under Ernest Lawrence at Lawrence Livermore National Laboratory. L ...
,
Frank Oppenheimer Frank Friedman Oppenheimer (August 14, 1912 – February 3, 1985) was an American particle physicist, cattle rancher, professor of physics at the University of Colorado, and the founder of the Exploratorium in San Francisco. A younger brother ...
,
J. Robert Oppenheimer J. Robert Oppenheimer (; April 22, 1904 – February 18, 1967) was an American theoretical physicist. A professor of physics at the University of California, Berkeley, Oppenheimer was the wartime head of the Los Alamos Laboratory and is oft ...
, William E. Parkins, Bernard Peters and
Joseph Slepian Joseph Slepian (February 11, 1891 – December 19, 1969) was an American electrical engineer known for his contributions to the developments of electrical apparatus and theory. Born in Boston, MA of Jewish Russian immigrants, he studied ma ...
. In November 1943 they were joined by a British Mission headed by Oliphant that included fellow Australian physicists
Harrie Massey Sir Harrie Stewart Wilson Massey (16 May 1908 – 27 November 1983) was an Australian mathematical physicist who worked primarily in the fields of atomic and atmospheric physics. A graduate of the University of Melbourne and Cambridge Unive ...
and
Eric Burhop Eric Henry Stoneley Burhop, (31 January 191122 January 1980) was an Australian physicist and humanitarian. A graduate of the University of Melbourne, Burhop was awarded an 1851 Exhibition Scholarship to study at the Cavendish Laboratory under ...
, and British physicists such as
Joan Curran Joan, Lady Curran (26 February 1916 – 10 February 1999), born Joan Elizabeth Strothers, was a Welsh physicist who played important roles in the development of radar and the atomic bomb during the Second World War. She invented chaff, a rad ...
and Thomas Allibone. Lawrence had a large cyclotron under construction at Berkeley, one with a magnet. This was converted into a calutron that was switched on for the first time on 26 May 1942. Like the 37-inch version, it looked like a giant C when viewed from above. The operator sat in the open end, whence the temperature could be regulated, the position of the electrodes adjusted, and even components replaced through an airlock while it was running. The new, more powerful calutron was not used to produce enriched uranium, but for experiments with multiple ion sources. This meant having more collectors, but it multiplied the throughput. The problem was that the beams interfered with each other, producing a series of oscillations called hash. An arrangement was devised that minimized the interference, resulting in reasonably good beams being produced, in September 1942. Robert Oppenheimer and
Stan Frankel Stanley Phillips Frankel (1919 – May, 1978) was an American computer scientist. He worked in the Manhattan Project and developed various computers as a consultant. Early life He was born in Los Angeles, attended graduate school at the Univers ...
invented the magnetic shim, a device used to adjust the homogeneity of a magnetic field. These were sheets of iron about in width that were bolted to the top and bottom of the vacuum tank. The effect of the shims was to slightly increase the magnetic field in such a way as to help focus the ion beam. Work would continue on the shims through 1943. The main calutron patents were ''Methods of and apparatus for separating materials'' (Lawrence), ''Magnetic shims'' (Oppenheimer and Frankel), and ''Calutron system'' (Lawrence). Burhop and Bohm later studied the characteristics of electric discharges in magnetic fields, today known as
Bohm diffusion The diffusion of plasma across a magnetic field was conjectured to follow the Bohm diffusion scaling as indicated from the early plasma experiments of very lossy machines. This predicted that the rate of diffusion was linear with temperature and ...
. Their papers on the properties of plasmas under magnetic containment would find usage in the post-war world in research into controlled
nuclear fusion Nuclear fusion is a reaction in which two or more atomic nuclei are combined to form one or more different atomic nuclei and subatomic particles ( neutrons or protons). The difference in mass between the reactants and products is manife ...
. Other technical problems were more mundane but no less important. Although the beams had low intensity, they could, over many hours of operation, still melt the collectors. A water cooling system was therefore added to the collectors and the tank liner. Procedures were developed for cleaning the "gunk" that condensed inside the vacuum tank. A particular problem was blockage of the slits by "crud", which caused the ion beams to lose focus, or stop entirely. The chemists had to find a way of producing quantities of uranium tetrachloride () from
uranium oxide Uranium oxide is an oxide of the element uranium. The metal uranium forms several oxides: * Uranium dioxide or uranium(IV) oxide (UO2, the mineral uraninite or pitchblende) * Diuranium pentoxide or uranium(V) oxide (U2O5) * Uranium trioxide o ...
. (Nier had used uranium bromide.) Initially, they produced it by using hydrogen to reduce
uranium trioxide Uranium trioxide (UO3), also called uranyl oxide, uranium(VI) oxide, and uranic oxide, is the hexavalent oxide of uranium. The solid may be obtained by heating uranyl nitrate to 400 °C. Its most commonly encountered polymorph, γ-UO3, is a ...
() to
uranium dioxide Uranium dioxide or uranium(IV) oxide (), also known as urania or uranous oxide, is an oxide of uranium, and is a black, radioactive, crystalline powder that naturally occurs in the mineral uraninite. It is used in nuclear fuel rods in nuclear re ...
(), which was then reacted with carbon tetrachloride () to produce uranium tetrachloride.
Charles A. Kraus Charles August Kraus (August 15, 1875 – June 27, 1967) was an American chemist. He was professor of chemistry and director of the chemical laboratories at Clark University, where he directed the Chemical Warfare Service during World War I. Lat ...
proposed a better method for large-scale production that involved reacting the uranium oxide with carbon tetrachloride at high temperature and pressure. This produced uranium pentachloride () and phosgene (). While nowhere near as nasty as the
uranium hexafluoride Uranium hexafluoride (), (sometimes called "hex") is an inorganic compound with the formula UF6. Uranium hexafluoride is a volatile white solid that reacts with water, releasing corrosive hydrofluoric acid. The compound reacts mildly with alumin ...
used by the gaseous diffusion process, uranium tetrachloride is
hygroscopic Hygroscopy is the phenomenon of attracting and holding water molecules via either absorption or adsorption from the surrounding environment, which is usually at normal or room temperature. If water molecules become suspended among the substan ...
, so work with it had to be undertaken in
glovebox A glovebox (or glove box) is a sealed container that is designed to allow one to manipulate objects where a separate atmosphere is desired. Built into the sides of the glovebox are gloves arranged in such a way that the user can place their hand ...
es that were kept dry with
phosphorus pentoxide Phosphorus pentoxide is a chemical compound with molecular formula P4 O10 (with its common name derived from its empirical formula, P2O5). This white crystalline solid is the anhydride of phosphoric acid. It is a powerful desiccant and dehydra ...
(). The presence of phosgene, a lethal gas responsible for 85 000 deaths as a
chemical weapon A chemical weapon (CW) is a specialized munition that uses chemicals formulated to inflict death or harm on humans. According to the Organisation for the Prohibition of Chemical Weapons (OPCW), this can be any chemical compound intended as a ...
during
World War I World War I (28 July 1914 11 November 1918), often abbreviated as WWI, was one of the deadliest global conflicts in history. Belligerents included much of Europe, the Russian Empire, the United States, and the Ottoman Empire, with fightin ...
, required that the chemists wear gas masks when handling it. Of the $19.6 million spent on research and development of the electromagnetic process, $18 million (92 percent) was spent at the Radiation Laboratory in Berkeley, and further work conducted at Brown University,
Johns Hopkins University Johns Hopkins University (Johns Hopkins, Hopkins, or JHU) is a private research university in Baltimore, Maryland. Founded in 1876, Johns Hopkins is the oldest research university in the United States and in the western hemisphere. It consi ...
and
Purdue University Purdue University is a public land-grant research university in West Lafayette, Indiana, and the flagship campus of the Purdue University system. The university was founded in 1869 after Lafayette businessman John Purdue donated land and mone ...
, and by the Tennessee Eastman corporation. During 1943, the emphasis shifted from research to development, engineering, and the training of workers to operate the production facilities at the
Clinton Engineer Works The Clinton Engineer Works (CEW) was the production installation of the Manhattan Project that during World War II produced the enriched uranium used in the 1945 bombing of Hiroshima, as well as the first examples of reactor-produced pluton ...
in Oak Ridge, Tennessee. By the middle of 1944, there were nearly 1,200 people working at the Radiation Laboratory.


Design

Much of the great progress on the electromagnetic process can be attributed to Lawrence's leadership style. His audacity, optimism and enthusiasm were contagious. His staff put in long hours, and University of California administrators sliced through red tape despite not knowing what the project was about. Government officials began to view the development of atomic bombs in time to affect the outcome of the war as a genuine possibility.
Vannevar Bush Vannevar Bush ( ; March 11, 1890 – June 28, 1974) was an American engineer, inventor and science administrator, who during World War II headed the U.S. Office of Scientific Research and Development (OSRD), through which almost all warti ...
, the director of the OSRD, which was overseeing the project, visited Berkeley in February 1942, and found the atmosphere there "stimulating" and "refreshing". On 9 March 1942, he reported to the president,
Franklin D. Roosevelt Franklin Delano Roosevelt (; ; January 30, 1882April 12, 1945), often referred to by his initials FDR, was an American politician and attorney who served as the 32nd president of the United States from 1933 until his death in 1945. As the ...
, that it might be possible to produce enough material for a bomb by mid-1943, based on new estimates from Robert Oppenheimer that the critical mass of a sphere of pure uranium-235 was between 2.0 and 2.5 kilograms. The experiments with the 184-inch magnet led to the construction of a prototype calutron called the XA. It contained a rectangular, three-coil magnet with a horizontal field in which the calutron tanks could stand side by side, with four vacuum tanks, each with a double source. At the 25 June 1942 meeting of the S-1 Executive Committee, which had superseded the S-1 Uranium Committee on 19 June, there was a proposal to build the electromagnetic plant at Oak Ridge, where the other
Manhattan Project The Manhattan Project was a research and development undertaking during World War II that produced the first nuclear weapons. It was led by the United States with the support of the United Kingdom and Canada. From 1942 to 1946, the project w ...
facilities would be located, for reasons of economy and security. Lawrence lodged an objection due to his desire to have the electromagnetic separation plant located much nearer to Berkeley. The
Shasta Dam Shasta Dam (called Kennett Dam before its construction) is a concrete arch-gravity dam across the Sacramento River in Northern California in the United States. At high, it is the List of tallest dams in the United States, eighth-tallest dam in ...
area in California remained under consideration for the electromagnetic plant until September 1942, by which time Lawrence had dropped his objection. The 25 June meeting also designated Stone & Webster as the primary contractor for the design and engineering. The Army assumed responsibility for the Manhattan Project on 17 September 1942, with
Brigadier General Brigadier general or Brigade general is a military rank used in many countries. It is the lowest ranking general officer in some countries. The rank is usually above a colonel, and below a major general or divisional general. When appointed ...
Leslie R. Groves, Jr., as director, although the Army did not formally take over the contracts with the University of California from the OSRD until 1 May 1943. Major Thomas T. Crenshaw, Jr., became California Area Engineer in August 1942, with Captain Harold A. Fidler, who soon replaced him, as his assistant. Crenshaw established his office in the Donner Laboratory at the University of California. In September 1942, the S-1 Executive Committee recommended that a five-tank pilot plant be built along with a 200-tank section of a production plant. Between October 1942 and November 1943, Groves paid monthly visits to the Radiation Laboratory in Berkeley. Reports indicated that compared to the alternatives of a gaseous diffusion plant or a
plutonium Plutonium is a radioactive chemical element with the symbol Pu and atomic number 94. It is an actinide metal of silvery-gray appearance that tarnishes when exposed to air, and forms a dull coating when oxidized. The element normally exhibi ...
-producing
nuclear reactor A nuclear reactor is a device used to initiate and control a fission nuclear chain reaction or nuclear fusion reactions. Nuclear reactors are used at nuclear power plants for electricity generation and in nuclear marine propulsion. Heat fr ...
, an electromagnetic plant would take longer and require more scarce materials to build, and need more manpower and more electricity to operate. The cost of a kilogram of fissile material would therefore be much greater. On the other hand, while the alternative processes still faced considerable technical obstacles, the electromagnetic process was proven to work, and could be built in stages that would immediately start producing fissile material. Groves cancelled the pilot plant on 14 November, in favor of proceeding immediately with the production plant. The Radiation Laboratory forwarded the preliminary designs for a production plant to Stone & Webster before the end of the year, but one important issue remained unsettled. Oppenheimer contended that
weapons-grade Weapons-grade nuclear material is any fissionable nuclear material that is pure enough to make a nuclear weapon or has properties that make it particularly suitable for nuclear weapons use. Plutonium and uranium in grades normally used in nucle ...
uranium would have to be 90% pure uranium-235. Edward Lofgren and Martin Kamen thought that this could not be achieved without a second stage of enrichment. The two stages became known as Alpha and Beta. In March 1943, Groves approved the construction of five Alpha and two Beta racetracks. In September, he authorized four more Alpha racetracks, which became known as Alpha II, along with two more Beta racetracks to process their product.


Construction

Construction of the electromagnetic plant at Oak Ridge, codenamed Y-12, commenced 18 February 1943. The facility would eventually comprise nine major process buildings and 200 other structures covering almost of floor space. The site in Bear Creek Valley southwest of the Oak Ridge township was selected in the hope that the surrounding ridge lines might contain a major explosion or nuclear accident. Problems with the substratum required the excavation crews to perform more blasting and excavation to provide adequate foundations for the heavy machinery in the facilities. Supplies and materials of all kinds poured in: 2,157 carloads of electrical equipment, 1,219 of heavy equipment, 5,389 of lumber, 1,407 of pipe and fittings, 1,188 of steel, 257 of valves, and 11 of welding electrodes. The racetracks required 85,000
vacuum tube A vacuum tube, electron tube, valve (British usage), or tube (North America), is a device that controls electric current flow in a high vacuum between electrodes to which an electric potential difference has been applied. The type known as ...
s. Where possible, off-the-shelf components were used, but all too many components of the calutrons were unique. Two purchasing departments were established, one in Boston near Stone & Webster for facility equipment, and the other at Oak Ridge for construction supplies. The Chief Engineer of the Manhattan District,
Colonel Colonel (abbreviated as Col., Col or COL) is a senior military officer rank used in many countries. It is also used in some police forces and paramilitary organizations. In the 17th, 18th and 19th centuries, a colonel was typically in charge o ...
James C. Marshall Brigadier General James Creel Marshall (15 October 1897 – 19 July 1977) was a United States Army Corps of Engineers officer who was initially in charge of the Manhattan Project to build an atomic bomb during World War II. A member of the Ju ...
, and his deputy, Lieutenant Colonel Kenneth D. Nichols, discovered that the electromagnetic isotope separation process would require of
copper Copper is a chemical element with the symbol Cu (from la, cuprum) and atomic number 29. It is a soft, malleable, and ductile metal with very high thermal and electrical conductivity. A freshly exposed surface of pure copper has a pinkis ...
, which was in desperately short supply. However, they realized that
silver Silver is a chemical element with the symbol Ag (from the Latin ', derived from the Proto-Indo-European ''h₂erǵ'': "shiny" or "white") and atomic number 47. A soft, white, lustrous transition metal, it exhibits the highest electrical ...
could be substituted, in an 11:10 ratio. On 3 August 1942, Nichols met with the
Under Secretary of the Treasury The United States Deputy Secretary of the Treasury, in the United States government, advises and assists the Secretary of the Treasury in the supervision and direction of the Department of the Treasury and its activities, and succeeds the Secret ...
, Daniel W. Bell, and asked for the transfer of silver bullion from the West Point Bullion Depository. Nichols later recalled the conversation: Eventually, of silver were used, then worth over $1 billion. Nichols had to provide a monthly accounting to the Treasury. The silver bars were taken under guard to the Defense Plant Corporation in
Carteret, New Jersey Carteret is a borough in Middlesex County, New Jersey, United States. As of the 2020 United States Census, the borough's population was 25,326. History Carteret was originally created as the borough of Roosevelt on April 11, 1906, from portion ...
, where they were cast into cylindrical billets, and then to
Phelps Dodge Phelps Dodge Corporation was an American mining company founded in 1834 as an import-export firm by Anson Greene Phelps and his two sons-in-law William Earle Dodge, Sr. and Daniel James. The latter two ran Phelps, James & Co., the part of the o ...
in Bayway, New Jersey, where they were extruded into strips thick, wide and long. Some 258 carloads were shipped under guard by rail to
Allis-Chalmers Allis-Chalmers was a U.S. manufacturer of machinery for various industries. Its business lines included agricultural equipment, construction equipment, power generation and power transmission equipment, and machinery for use in industrial set ...
in
Milwaukee, Wisconsin Milwaukee ( ), officially the City of Milwaukee, is both the most populous and most densely populated city in the U.S. state of Wisconsin and the county seat of Milwaukee County, Wisconsin, Milwaukee County. With a population of 577,222 at th ...
, where they were wound onto magnetic coils and sealed into welded casings. Finally, they moved by unguarded flatcars to the Clinton Engineer Works. There, special procedures were instituted for handling the silver. When they had to drill holes in it, they did so over paper so that the filings could be collected. After the war, all the machinery was dismantled and cleaned and the floorboards beneath the machinery were ripped up and burned to recover minute amounts of silver. In the end, only 1/3,600,000th was lost. In May 1970, the last of silver was replaced with copper and returned to the Treasury. The XAX racetrack with two tanks and three coils was ready to train workers in August 1943. Bugs were discovered, but were not aggressively followed up. The first Alpha process building, 9201-1, was completed on 1 November 1943. When the first racetrack was started up for testing on schedule in November, the 14-ton vacuum tanks crept out of alignment by as much as because of the power of the magnets and had to be fastened more securely. A more serious problem arose when the magnetic coils started shorting out. In December Groves ordered a magnet broken open, and handfuls of rust were found inside. Moisture was also a problem in its own right, as was the winding of the wire, which was too tight. Groves ordered the racetracks to be torn down and the magnets sent back to the factory to be cleaned and rewound. Rigid standards for preparation and cleanliness were instituted to prevent a recurrence of these problems. Training for the Beta tracks shifted from the XAX to the XBX training and development racetrack in November 1943. A second Alpha I racetrack became operational in January 1944. The first Beta racetrack and the third and first Alpha racetracks, now repaired, became operational in March 1944, and the fourth Alpha racetrack in April 1944. A third building, 9201-3, contained a fifth racetrack that incorporated some modifications, and was known as Alpha I. This became operational on 3 June 1944. Work on the Alpha and Beta chemistry buildings, 9202 and 9203, commenced in February 1943, and was completed in September. Work on the Beta process building, 9204-1, began in May 1943, and was ready for operation on 13 March 1944, but was not completed until September 1944. Groves authorized Alpha II in September 1943. This consisted of two new Alpha process buildings, 9201-4 and 9201-5, another Beta, 9204-2, an extension to the Alpha chemistry building, and a new Beta chemistry building, 9206. When 9206 opened, the old Beta chemistry building, 9203, was converted into a laboratory. Work started on the new Alpha II process buildings on 2 November 1943; the first racetrack was completed in July 1944, and all four were operational by 1 October 1944. The Alpha II racetracks were configured in a linear layout rather than an oval, although they were still called racetracks. In all, there were 864 Alpha calutrons, arranged in nine racetracks of 96. There were only 36 calutrons in each Beta racetrack, for a total of 288 calutrons, although only 216 of them were ever operated. Work on the new Beta process building commenced on 20 October 1943. Equipment installation began on 1 April 1944, and it was ready for use on 10 September 1944. A third Beta process building, 9204-3, was authorized in May 1944 to process the output of the
K-25 K-25 was the codename given by the Manhattan Project to the program to produce enriched uranium for atomic bombs using the gaseous diffusion method. Originally the codename for the product, over time it came to refer to the project, the prod ...
gaseous diffusion plant. It was completed on 15 May 1945. A fourth Beta process building, 9204-4, was authorized on 2 April 1945 and was completed by 1 December 1945. A new group of Alpha chemistry buildings known as the 9207 group was commenced in June 1944, but work was halted in June 1945 before they were completed. Along with these main buildings, there were offices, workshops, warehouses and other structures. There were two steam plants for heating, and a power plant for electricity.


Operations

The Alpha racetracks were a 24-fold magnification of the XA calutron that could hold 96 calutron Alpha tanks. The calutrons were upright and arrayed facing each other in pairs of inner and outer machines. To minimize magnetic losses, and to economize on steel consumption, the assembly was curved into an oval shape that formed a closed magnetic loop long, wide and high, in the shape of a racetrack; hence the name. The two Alpha I buildings, 9201-1 and 9201-2, each contained two racetracks, with only one in the Alpha I, 9201-3. The Beta racetracks were smaller, linear in shape, and optimized for recovery rather than production, with only 36 instead of 96 process bins. The four Alpha II racetracks were also linear in configuration. They incorporated many improvements, the most important being that they had four sources instead of just two. They also had improved magnets and vacuum systems. Tennessee Eastman was hired to manage Y-12 on the usual cost plus fixed fee basis, with a fee of $22,500 per month plus $7,500 per racetrack for the first seven racetracks and $4,000 per additional racetrack. Workers were recruited in the Knoxville area. The typical recruit was a young woman, a recent graduate of a local high school. Training was initially conducted at the
University of Tennessee The University of Tennessee (officially The University of Tennessee, Knoxville; or UT Knoxville; UTK; or UT) is a public land-grant research university in Knoxville, Tennessee. Founded in 1794, two years before Tennessee became the 16th state ...
. Training switched to Berkeley from April to September 1943, where it was conducted on the XA calutron and a 1:16 scale model of the Alpha racetrack, and then to Oak Ridge when the XAX calutron became available. Some 2,500 operators would be required once all the Alpha II calutrons were available. The Tennessee Eastman payroll at Y-12 ballooned from 10,000 in mid-1944 to 22,482 in August 1945. For security reasons, the trainees were not informed of the purpose of the equipment they were taught to operate. The calutrons were initially operated by scientists from Berkeley to remove bugs and achieve a reasonable operating rate. Then the Tennessee Eastman operators took over. Nichols compared unit production data, and pointed out to Lawrence that the young "hillbilly" girl operators were outproducing his Ph.Ds. They agreed to a production race and Lawrence lost, a morale boost for the " Calutron Girls" (called Cubicle Operators at the time) and their supervisors. The women were trained like soldiers not to reason why, while "the scientists could not refrain from time-consuming investigation of the cause of even minor fluctuations of the dials". For a while, the calutrons suffered from a series of debilitating breakdowns and equipment failures, exacerbated by a shortage of spare parts. Hopes that the Alpha II racetracks would be more reliable soon faded, as they were plagued by insulator failures. These problems were gradually overcome. The first shipments of enriched uranium to the Manhattan Project's
Los Alamos Laboratory The Los Alamos Laboratory, also known as Project Y, was a secret laboratory established by the Manhattan Project and operated by the University of California during World War II. Its mission was to design and build the first atomic bombs. Ro ...
were made in March 1944, consisting of Alpha product enriched to 13 to 15 percent uranium-235. While of no use in a bomb, it was urgently required for experiments with enriched uranium. The last shipment of Alpha product was made on 11 May 1944. On 7 June 1944, Y-12 made its first delivery of
weapons-grade Weapons-grade nuclear material is any fissionable nuclear material that is pure enough to make a nuclear weapon or has properties that make it particularly suitable for nuclear weapons use. Plutonium and uranium in grades normally used in nucle ...
Beta product, enriched to as high as 89% uranium-235. A major problem was that of loss of feed material and product. Only 1 part in 5,825 of the feed material became finished product. About 90 percent was splattered over the feed bottles or vacuum tanks. The problem was particularly acute with the enriched feed of the Beta calutrons. Extraordinary efforts were made to recover product, including burning the carbon receiver liners to recover the uranium in them. Despite everything, some 17.4 percent of Alpha product and 5.4 percent of Beta product was lost.
Frank Spedding Frank Harold Spedding (22 October 1902 – 15 December 1984) was a Canadian American chemist. He was a renowned expert on rare earth elements, and on extraction of metals from minerals. The uranium extraction process helped make it possible for ...
from the Manhattan Project's
Ames Laboratory Ames National Laboratory, formerly Ames Laboratory, is a United States Department of Energy national laboratory located in Ames, Iowa, and affiliated with Iowa State University. It is a top-level national laboratory for research on national sec ...
and
Philip Baxter Sir John Philip Baxter (7 May 1905 – 5 September 1989) was a British chemical engineer. He was the second director of the University of New South Wales from 1953, continuing as vice-chancellor when the position's title was changed in 1955. Un ...
from the British Mission were sent to advise on improvements to recovery methods. The death of a worker from exposure to phosgene also prompted a search for a safer production process. In February 1945, slightly enriched 1.4 percent uranium-235 feed material began arriving from the S-50 liquid thermal diffusion plant. Shipments of product from S-50 were discontinued in April. S-50 product was fed into K-25 instead. In March 1945, Y-12 began receiving feed enriched to 5 percent from K-25. The output of these plants was in the form of uranium hexafluoride (). It was converted to uranium trioxide, which then went into the usual process for conversion to uranium tetrachloride. On 5 August 1945, K-25 started producing feed enriched to 23 percent, enough to be fed straight into the Beta racetracks. The remaining Alpha product was then fed into K-25. By September 1945, the calutrons had produced 88 kilograms of product with an average enrichment of 84.5 percent, and the Beta racetracks turned out another 953 kilograms enriched to 95 percent by the end of the year. Enriched uranium from the calutrons provided the fissile component of the
Little Boy "Little Boy" was the type of atomic bomb dropped on the Japanese city of Hiroshima on 6 August 1945 during World War II, making it the first nuclear weapon used in warfare. The bomb was dropped by the Boeing B-29 Superfortress ''Enola Gay'' p ...
atomic bomb used in the
atomic bombing of Hiroshima The United States detonated two atomic bombs over the Japanese cities of Hiroshima and Nagasaki on 6 and 9 August 1945, respectively. The two bombings killed between 129,000 and 226,000 people, most of whom were civilians, and remain the onl ...
in August 1945. With the war over, the Alpha tracks began to suspend operations on 4 September 1945, and ceased operation completely on 22 September. The last two Beta tracks went into full operation in November and December 1945, processing feed from K-25 and the new K-27 gaseous diffusion plant. By May 1946, studies suggested that the gaseous diffusion plants could fully enrich the uranium by themselves without accidentally creating a critical mass. After a trial demonstrated that this was the case, Groves ordered all but one Beta track shut down in December 1946. The total cost of the electromagnetic project up to the end of the Manhattan Project on 31 December 1946 was $ (equivalent to $ in ).


Postwar years

The workforce at Y-12 dropped from a wartime peak of 22,482 on 21 August 1945 to less than 1,700 in 1949. All the calutrons were removed and dismantled, except for the XAX and XBX training tracks in Building 9731, and the Beta 3 racetracks in Building 9204–3. In 1947,
Eugene Wigner Eugene Paul "E. P." Wigner ( hu, Wigner Jenő Pál, ; November 17, 1902 – January 1, 1995) was a Hungarian-American theoretical physicist who also contributed to mathematical physics. He received the Nobel Prize in Physics in 1963 "for his co ...
, the director of the
Oak Ridge National Laboratory Oak Ridge National Laboratory (ORNL) is a U.S. multiprogram science and technology national laboratory sponsored by the U.S. Department of Energy (DOE) and administered, managed, and operated by UT–Battelle as a federally funded research an ...
(ORNL), asked the Atomic Energy Commission for permission to use the Beta calutrons to produce isotopes for physics experiments. Permission was granted, and a wide range of isotopes was produced.
Lithium-6 Naturally occurring lithium (3Li) is composed of two stable isotopes, lithium-6 and lithium-7, with the latter being far more abundant on Earth. Both of the natural isotopes have an unexpectedly low nuclear binding energy per nucleon ( for ...
from the Beta calutrons was used for research into thermonuclear weapons. Many other isotopes were used for peaceful scientific and medical purposes. The Beta 3 racetracks were transferred to the ORNL in March 1950. By the mid-1950s, the Beta calutrons had produced quantities of all the naturally occurring stable isotopes except those of osmium, which had to wait until April 1960. The calutrons continued to produce isotopes until 1998. , they are still on standby. Like the United States, the Soviet Union (USSR) carried out research on multiple enrichment technologies for the Soviet atomic bomb project. A trial electromagnetic process was carried out in 1946 with a calutron using a magnet taken from Germany. A site was chosen for an electromagnetic plant at Sverdlovsk-45 in 1946. The pilot plant, known as Plant 418, was completed in 1948. A more efficient design was developed in which the particle beams were bent by 225° instead of 180° as in the American calutron. It was used to complete the uranium enrichment process after technical difficulties were encountered with the gaseous diffusion process. Uranium enriched to about 40 percent uranium-235 was brought to Sverdlovsk-45 for final enrichment to between 92 and 98 percent. After the problems with the gaseous diffusion process were resolved in 1950, it was decided not to proceed with a full-scale electromagnetic plant. , it remains operational. In 1969, a research calutron known as S-2 was built at All-Russian Scientific Research Institute of Experimental Physics, Arzamas-16 for high-efficiency separation of isotopes of heavy elements like plutonium. In 1945, the Nuclear weapons and the United Kingdom, British atomic bomb project built a 180° calutron, similar in design to an American Beta calutron, at the Atomic Energy Research Establishment at Harwell, Oxfordshire. Owing to the success of the gaseous diffusion plant at Capenhurst, electromagnetic separation was not pursued by the United Kingdom, and the calutron was used to separate isotopes for research. The 180° design was not ideal for this purpose, so Harwell built a 90° calutron, HERMES, the "Heavy Elements and Radioactive Material Electromagnetic Separator". It was inspired by France's SIDONIE and PARIS separators at the Laboratoire René Bernas of the University of Paris, University of Paris IX in Orsay, and PARSIFAL at the military research laboratory of the Commissariat à l'énergie atomique et aux énergies alternatives in Bruyères-le-Châtel. Israel, Japan and France also built some research calutrons, including the SOLIS and MEIRA separators at the Soreq Nuclear Research Center. There is also CERN's On-Line Isotope Mass Separator, Isotope Separator On-Line Detector (ISOLDE), which was built in 1967. Four research and production calutrons were built at the China Institute of Atomic Energy in Beijing of identical design to those of the USSR in the early 1960s. A calutron at the Saha Institute of Nuclear Physics at Salt Lake City (Bidhan Nagar), Kolkata, Bidhan Nagar in India was used to produce plutonium for Smiling Buddha, India's first nuclear test on 18 May 1974. After the 1990–91 Gulf War, UNSCOM determined that Iraq had been pursuing a calutron program to enrich uranium. Iraq chose to develop the electromagnetic process over more modern, economic, and efficient methods of enrichment because calutrons were easier to build, with fewer technical challenges, and the components required to build them were not subject to export controls. At the time the program was discovered, Iraq was estimated to be two or three years away from producing enough material for nuclear weapons. The program was destroyed in the Gulf War. Consequently, the Nuclear Suppliers Group added the electromagnetic separation equipment to its guidelines for transfers of nuclear-related dual-use equipment, material and technology.


Notes


References

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Further reading

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External links

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Link to a site about a Calutron operator (Gladys Owens), and a famous picture of her at work.
{{Portal bar, History of Science, Nuclear technology, World War II Isotope separation History of the Manhattan Project Mass spectrometry Particle physics facilities University of California, Berkeley Uranium