Ventral lateral nucleus
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The ventral lateral nucleus (VL) is a nucleus in the
ventral nuclear group The ventral nuclear group is a collection of nuclei on the ventral side of the thalamus. According to MeSH, it consists of the following: * ventral anterior nucleus * ventral lateral nucleus * ventral posterior nucleus – this is made up of two n ...
of the
thalamus The thalamus (from Greek θάλαμος, "chamber") is a large mass of gray matter located in the dorsal part of the diencephalon (a division of the forebrain). Nerve fibers project out of the thalamus to the cerebral cortex in all directions, ...
.


Inputs and outputs

It receives neuronal inputs from the
basal ganglia The basal ganglia (BG), or basal nuclei, are a group of subcortical nuclei, of varied origin, in the brains of vertebrates. In humans, and some primates, there are some differences, mainly in the division of the globus pallidus into an exter ...
which includes the substantia nigra and the globus pallidus (via the thalamic fasciculus). It also has inputs from the cerebellum (via the dentatothalamic tract). It sends neuronal output to the primary motor cortex and
premotor cortex The premotor cortex is an area of the motor cortex lying within the frontal lobe of the brain just anterior to the primary motor cortex. It occupies part of Brodmann's area 6. It has been studied mainly in primates, including monkeys and humans ...
. The ventral lateral nucleus in the thalamus forms the motor functional division in the
thalamic nuclei This traditional list does not accord strictly with human thalamic anatomy. Nuclear groups of the thalamus include: *anterior nuclear group ** anteroventral nucleus ** anterodorsal nucleus ** anteromedial nucleus **superficial ("lateral dorsal" ...
along with the
ventral anterior nucleus The ventral anterior nucleus (VA) is a nucleus of the thalamus. It acts with the anterior part of the ventral lateral nucleus to modify signals from the basal ganglia. Inputs and outputs The ventral anterior nucleus receives neuronal inputs from t ...
. The ventral lateral nucleus receives motor information from the cerebellum and the globus pallidus. Output from the ventral lateral nucleus then goes to the primary motor cortex.


Functions

The function of the ventral lateral nucleus is to target efferents including the motor cortex, premotor cortex, and supplementary motor cortex. Therefore, its function helps the coordination and planning of movement. It also plays a role in the learning of movement.Crosson, B., (1992). Subcortical Functions in Language and Memory. New York: The Guliford Press.


Clinical significance

A lesion of the VL has been associated with synesthesia.


Additional images

File:Constudthal.gif, Thalamus File:Territoriostalamo.svg, Thalamus


References


External links

* {{Neural tracts Thalamus