Trional (Methylsulfonal) is a

sedative-hypnotic A sedative or tranquilliser is a substance that induces sedation by reducing irritability or excitement. They are CNS depressants and interact with brain activity causing its deceleration. Various kinds of sedatives can be distinguished, but t ...

and

anesthetic An anesthetic (American English) or anaesthetic (British English; see spelling differences) is a drug used to induce anesthesia ⁠— ⁠in other words, to result in a temporary loss of sensation or awareness. They may be divided into two ...

drug with GABAergic

action Action may refer to: * Action (narrative), a literary mode * Action fiction, a type of genre fiction * Action game, a genre of video game Film * Action film, a genre of film * ''Action'' (1921 film), a film by John Ford * ''Action'' (1980 fil ...

s. It has similar effects to sulfonal, except it is faster acting.

History

Trional was prepared and introduced by

Eugen Baumann Eugen Baumann (12 December 1846 – 3 November 1896) was a German chemist. He was one of the first people to create polyvinyl chloride (PVC), and, together with Carl Schotten, he discovered the Schotten-Baumann reaction. Life Baumann was born i ...

and Alfred Kast in 1888. Appeared in Agatha Christie's "

Murder on the Orient Express ''Murder on the Orient Express'' is a work of detective fiction by English writer Agatha Christie featuring the Belgian detective Hercule Poirot. It was first published in the United Kingdom by the Collins Crime Club on 1 January 1934. In the U ...

", "

And Then There Were None ''And Then There Were None'' is a mystery novel by the English writer Agatha Christie, described by her as the most difficult of her books to write. It was first published in the United Kingdom by the Collins Crime Club on 6 November 1939, as ...

" and other novels such as John Bude’s “

The Lake District Murder ''The Lake District Murder'' is a 1935 detective novel by the British writer John Bude.Hubin p.56 It is the first in a series of novels featuring Chief Inspector Meredith, promoted at the end of case to Superintendent. Set in the Lake District of ...

” as a sleep inducing sedative, and in In Search of Lost Time (Sodom and Gomorrah) by Marcel Proust as a hypnotic.

Sax Rohmer Arthur Henry "Sarsfield" Ward (15 February 1883 – 1 June 1959), better known as Sax Rohmer, was an English novelist. He is best remembered for his series of novels featuring the master criminal Dr. Fu Manchu."Rohmer, Sax" by Jack Adrian in Da ...

also references trional in his novel '' Dope''.

References

Hypnotics GABAA receptor positive allosteric modulators Sulfones {{sedative-stub

History

See also

References