Tooth and nail syndrome (also known as "Hypodontia with nail dysgenesis,"
and "Witkop syndrome"
) is a rare disorder, first described in 1965, characterized by nails that are thin, small, and friable, and which may show
koilonychia
Koilonychia, also known as spoon nails,James, William; Berger, Timothy; Elston, Dirk (2005). ''Andrews' Diseases of the Skin: Clinical Dermatology''. (10th ed.). Saunders. . is a nail disease that can be a sign of hypochromic anemia, especially ...
at birth.
[Freedberg, et al. (2003). ''Fitzpatrick's Dermatology in General Medicine''. (6th ed.). McGraw-Hill. .]
It is associated with ''
MSX1
Homeobox protein MSX-1, is a protein that in humans is encoded by the ''MSX1'' gene. MSX1 transcripts are not only found in thyrotrope-derived TSH cells, but also in the TtT97 thyrotropic tumor, which is a well differentiated hyperplastic tissue ...
''.
See also
*
Skin lesion
A skin condition, also known as cutaneous condition, is any medical condition that affects the integumentary system—the organ system that encloses the body and includes skin, nails, and related muscle and glands. The major function of th ...
*
List of cutaneous conditions
References
External links
Genodermatoses
Syndromes
{{Genodermatoses-stub