Tolfenamic acid (Clotam, Tufnil) is a member of the
anthranilic acid derivatives (or fenamate) class of
NSAID
Non-steroidal anti-inflammatory drugs (NSAID) are members of a therapeutic drug class which reduces pain, decreases inflammation, decreases fever, and prevents blood clots. Side effects depend on the specific drug, its dose and duration of ...
drugs discovered by scientists at Medica Pharmaceutical Company in Finland. Like other members of the class, it is a
COX inhibitor and prevents formation of
prostaglandins
The prostaglandins (PG) are a group of physiologically active lipid compounds called eicosanoids having diverse hormone-like effects in animals. Prostaglandins have been found in almost every tissue in humans and other animals. They are deri ...
.
[
It is used in the UK as a treatment for ]migraine
Migraine (, ) is a common neurological disorder characterized by recurrent headaches. Typically, the associated headache affects one side of the head, is pulsating in nature, may be moderate to severe in intensity, and could last from a few hou ...
. It is generally not available in the US.[NIH LiverTox Databas]
Mefenamic Acid
Last updated June 23, 2015. Page accessed July 3, 2015. Quote: "(fenamates generally not available in the United States, such as tolfenamic acid and flufenamic acid)" It is available in some Asian, Latin American and European countries as a generic drug
A generic drug is a pharmaceutical drug that contains the same chemical substance as a drug that was originally protected by chemical patents. Generic drugs are allowed for sale after the patents on the original drugs expire. Because the active c ...
for humans and for animals.[Drugs.co]
Drugs.com international listings for tolfenamic acid
Page accessed July 3, 2015
References
External links
(Diseases Database)
Nonsteroidal anti-inflammatory drugs
Antipyretics
Analgesics
Chloroarenes
Anthranilic acids
GABAA receptor positive allosteric modulators
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