Tata Memorial Hospital
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The Tata Memorial Hospital is situated in
Parel Parel ( ISO: Paraḷ, pronunciation: əɾəɭ is a neighbourhood of Mumbai. Parel used to have a number of textile mills, but these have been replaced by commercial office space development. History Originally, Parel was a separate islan ...
,
Mumbai Mumbai (, ; also known as Bombay — the official name until 1995) is the capital city of the Indian state of Maharashtra and the ''de facto'' financial centre of India. According to the United Nations, as of 2018, Mumbai is the secon ...
, in
India India, officially the Republic of India (Hindi: ), is a country in South Asia. It is the List of countries and dependencies by area, seventh-largest country by area, the List of countries and dependencies by population, second-most populous ...
. Also popularly known as TMH. It is a specialist
cancer Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. These contrast with benign tumors, which do not spread. Possible signs and symptoms include a lump, abnormal b ...
treatment and research centre, closely associated with the Advanced Centre for Treatment, Research and Education in Cancer (ACTREC). The centre is the national comprehensive cancer centre for the prevention, treatment, education and research in cancer and is recognized as one of the leading cancer centres in this part of the world. It is an autonomous body funded and controlled by
Department of Atomic Energy The Department of Atomic Energy (DAE) (IAST: ''Paramāṇu Ūrjā Vibhāga'') is a department with headquarters in Mumbai, Maharashtra, India. DAE was established in 1954 by a Presidential Order. DAE has been engaged in the development of nuc ...
, Government of India which also oversees the administration of institute since 1962. The Tata Memorial Hospital was initially commissioned by the
Sir Dorabji Tata Trust The Sir Dorabji Tata Trust was established by Sir Dorab Tata (fondly called ''Sir Dorabji''), the elder son of Tata Group founder Jamsetji Tata. Founded in 1932, it is one of the oldest non-sectarian philanthropic organisations in India. Histo ...
on 28 February 1941 as a center with enduring value and a mission for concern for the Indian people. Current Director of the hospital is Dr. Rajendra A Badwe, who took over from for director Dr. K. A. Dinshaw.


History

The Tata Memorial Hospital was founded by the Sir Dorabji Tata Trust on 28 February 1941. In 1952 the Indian Cancer Research Centre was established as a pioneer research institute for basic research—later called the Cancer Research Institute (CRI). In 1957 the Ministry of Health took over the Tata Memorial Hospital. The transfer of the administrative control of the Tata Memorial Centre (Tata Memorial Hospital & Cancer Research Institute) to the Department of Atomic Energy in 1962 was the next major milestone. The Tata Memorial Hospital and Cancer Research Institute merged as the two arms of the Tata Memorial Centre (TMC) in 1966 as a classic example of private philanthropy augmented by Government support with a mandate for Service, Education & Research in cancer.


Patient care

The Department of Surgical Oncology provides minimal access surgeries, skull-base procedures, major vascular replacements, limb salvage, microvascular surgery and robotic surgeries. The department conducts investigator-initiated and sponsored research studies. Staff members contribute chapters to various books and author numerous publications in international peer reviewed journals. The department trains national and international residents and fellows providing exposure to basic and advanced surgical techniques and hands on courses in collaboration with external clinical labs. One of the fields of specialization of this hospital is in the treatment of
acute lymphoblastic leukemia Acute lymphoblastic leukemia (ALL) is a cancer of the lymphoid line of blood cells characterized by the development of large numbers of immature lymphocytes. Symptoms may include feeling tired, pale skin color, fever, easy bleeding or bruis ...
(A.L.L). Every year nearly 30,000 new patients visit the clinics from all over India and neighboring countries. Nearly 60% of these cancer patients receive primary care at the Hospital of which over 70% are treated almost free of any charges. Over 1,000 patients attend the OPD daily for medical advice or for follow-up treatment. During the year 2003, over 20,000 new cases were registered in addition to over 13,000 Referral Cards issued for only special investigations. Nearly 8,500 major operations are performed annually and 5,000 patients treated with
Radiotherapy Radiation therapy or radiotherapy, often abbreviated RT, RTx, or XRT, is a therapy using ionizing radiation, generally provided as part of cancer treatment to control or kill malignant cells and normally delivered by a linear accelerator. Rad ...
and
Chemotherapy Chemotherapy (often abbreviated to chemo and sometimes CTX or CTx) is a type of cancer treatment that uses one or more anti-cancer drugs (chemotherapeutic agents or alkylating agents) as part of a standardized chemotherapy regimen. Chemother ...
annually in multi-disciplinary programmes delivering established treatments. The TMH was the first Centre in the country to initiate
Bone Marrow Transplant Hematopoietic stem-cell transplantation (HSCT) is the transplantation of multipotent hematopoietic stem cells, usually derived from bone marrow, peripheral blood, or umbilical cord blood in order to replicate inside of a patient and to produce ...
in 1983.
PET-CT Positron emission tomography–computed tomography (better known as PET-CT or PET/CT) is a nuclear medicine technique which combines, in a single gantry, a positron emission tomography (PET) scanner and an x-ray computed tomography (CT) scan ...
scanner has been procured to make this technology available for cancer management. In an effort to provide access to patients and their families who lack access or the means to visit the hospital, TMH has started an initiative to provide an online expert opinion through ''Navya.''


Preventive oncology

The Department of Preventive Oncology which was commissioned in the year 1993, gives a special focus on education in
cancer prevention Cancer prevention is the practice of taking active measures to decrease the incidence of cancer and mortality. The practice of prevention is dependent upon both individual efforts to improve lifestyle and seek preventive screening, and socioeconom ...
and early detection, cancer screening. Of the 2–2.5 million cases of cancer in the country, more than 70% of cases are detected late and report for treatment in very advanced stages. The emphasis on early detection would go a long way to dealing with the large numbers as well as to mitigate avoidable suffering and a financial burden.


ACTREC

The Advanced Centre for Treatment, Research, and Education in Cancer (ACTREC) is a new R&D satellite of the Tata Memorial Centre (TMC). It has the mandate to function as a national center for treatment, education, and research in cancer. ACTREC comprises two arms—a basic research arm constituted by the erstwhile Cancer Research Institute (CRI) which has shifted from the
Parel Parel ( ISO: Paraḷ, pronunciation: əɾəɭ is a neighbourhood of Mumbai. Parel used to have a number of textile mills, but these have been replaced by commercial office space development. History Originally, Parel was a separate islan ...
Campus to the new location in August 2002, and a Clinical Research Centre (CRC), The latter comprises a 50-bed research hospital which is equipped with diagnostic and therapeutic facilities. In the first phase, the focus will be o
Pediatric Oncology
and emerging therapies, including
gene therapy Gene therapy is a Medicine, medical field which focuses on the genetic modification of cells to produce a therapeutic effect or the treatment of disease by repairing or reconstructing defective genetic material. The first attempt at modifying ...
. Research investigations at CRI currently focus on molecular mechanisms responsible for the causation of major human cancers relevant to India. It is envisaged that in the future, ACTREC will play a greater role in drug development and emerging therapies for treatment and prevention of cancer. The
radiotherapy Radiation therapy or radiotherapy, often abbreviated RT, RTx, or XRT, is a therapy using ionizing radiation, generally provided as part of cancer treatment to control or kill malignant cells and normally delivered by a linear accelerator. Rad ...
at ACTREC is equipped with a dual-energy linear accelerator,
IMRT Radiation therapy or radiotherapy, often abbreviated RT, RTx, or XRT, is a therapy using ionizing radiation, generally provided as part of cancer treatment to control or kill malignant cells and normally delivered by a linear accelerator. Radia ...
, stereotactic therapy and HDU-
brachytherapy Brachytherapy is a form of radiation therapy where a sealed radiation source is placed inside or next to the area requiring treatment. ''Brachy'' is Greek for short. Brachytherapy is commonly used as an effective treatment for cervical, pro ...
units. The centre is committed to carrying out clinical trials under GCP conditions, including Phase I/II trials for investigational new drugs. In addition, the centre would specialize in cancer genetics including counseling and genetic testing and molecular pathology.


Cancer Research Institute (CRI)

Several studies are ongoing in Cancer Research Institute (CRI), Such as analysis of
cytokine Cytokines are a broad and loose category of small proteins (~5–25 kDa) important in cell signaling. Cytokines are peptides and cannot cross the lipid bilayer of cells to enter the cytoplasm. Cytokines have been shown to be involved in au ...
profiles and the role of antibodies to the viral proteins E6 and E7 in
cervical cancer Cervical cancer is a cancer arising from the cervix. It is due to the abnormal growth of cells that have the ability to invade or spread to other parts of the body. Early on, typically no symptoms are seen. Later symptoms may include abnormal ...
, cytokine imbalance in
lung cancer Lung cancer, also known as lung carcinoma (since about 98–99% of all lung cancers are carcinomas), is a malignant lung tumor characterized by uncontrolled cell growth in tissues of the lung. Lung carcinomas derive from transformed, mali ...
patients, and the role of urinary cytokines in intravesical BCG therapy in superficial
bladder cancer Bladder cancer is any of several types of cancer arising from the tissues of the urinary bladder. Symptoms include blood in the urine, pain with urination, and low back pain. It is caused when epithelial cells that line the bladder become ma ...
. The biology of
HIV-2 The subtypes of HIV include two major types, HIV type 1 (HIV-1) and HIV type 2 (HIV-2). HIV-1 is related to viruses found in chimpanzees and gorillas living in western Africa, while HIV-2 viruses are related to viruses found in the sooty mangabe ...
, the virus which has spread only in India and
Africa Africa is the world's second-largest and second-most populous continent, after Asia in both cases. At about 30.3 million km2 (11.7 million square miles) including adjacent islands, it covers 6% of Earth's total surface area ...
is being studied in-depth. Studies on tobacco mediated
carcinogenesis Carcinogenesis, also called oncogenesis or tumorigenesis, is the formation of a cancer, whereby normal cells are transformed into cancer cells. The process is characterized by changes at the cellular, genetic, and epigenetic levels and abnor ...
have encompassed chemical analysis, Sizeable effort has been directed towards delineation of the mechanisms of
chemopreventive Chemotherapy (often abbreviated to chemo and sometimes CTX or CTx) is a type of cancer treatment that uses one or more anti-cancer drugs (chemotherapeutic agents or alkylating agents) as part of a standardized chemotherapy regimen. Chemotherap ...
action of agents from Indian foods, such as
turmeric Turmeric () is a flowering plant, ''Curcuma longa'' (), of the ginger family, Zingiberaceae, the rhizomes of which are used in cooking. The plant is a perennial, rhizomatous, herbaceous plant native to the Indian subcontinent and Southeast ...
, tea and grapes, and development of mechanism-based
biomarkers In biomedical contexts, a biomarker, or biological marker, is a measurable indicator of some biological state or condition. Biomarkers are often measured and evaluated using blood, urine, or soft tissues to examine normal biological processes, pa ...
of exposure. The first
transgenic A transgene is a gene that has been transferred naturally, or by any of a number of genetic engineering techniques, from one organism to another. The introduction of a transgene, in a process known as transgenesis, has the potential to change the ...
mouse in the country, which was made at the institute, hosts a gene for a growth modulator. This mouse is being developed as a model for
squamous cell carcinoma Squamous-cell carcinomas (SCCs), also known as epidermoid carcinomas, comprise a number of different types of cancer that begin in squamous cells. These cells form on the surface of the skin, on the lining of hollow organs in the body, and on the ...
. In parallel, newer cell lines useful for cancer research and an expression system for the E6 protein of HPV are being developed. During 2002, scientists at the Institute have obtained extramural support from different funding bodies to the tune of Rs. 100,000,000. Work from the institute has led to 19 publications in peer-reviewed journals. Its current director is Dr. Sudeep Gupta


Tata Clinic

A 12-story block "The Tata Clinic and Faculty Block" has recently been constructed on the premises vacated by the CRI. This facility will house site specialty clinics, 50 additional beds, Minor theatre complex, daycare beds, academic offices, postgraduate education, seminar rooms, and a Telemedicine Centre. It is renamed as "Homi Bhabha Block"


Education

The Tata Memorial Centre is a recognised training centre for cancer education and research by national and international organisations such as
WHO Who or WHO may refer to: * Who (pronoun), an interrogative or relative pronoun * Who?, one of the Five Ws in journalism * World Health Organization Arts and entertainment Fictional characters * Who, a creature in the Dr. Seuss book '' Horton He ...
,
IAEA The International Atomic Energy Agency (IAEA) is an intergovernmental organization that seeks to promote the peaceful use of nuclear energy and to inhibit its use for any military purpose, including nuclear weapons. It was established in 195 ...
and UICC. Tata Memorial Hospital is a post-graduate teaching centre and is affiliated to the
University of Mumbai The University of Mumbai is a collegiate, state-owned, public research university in Mumbai. The University of Mumbai is one of the largest universities in the world. , the university had 711 affiliated colleges. Ratan Tata is the appointed h ...
,
National Board of Examinations National Board of Examinations (NBE) is an autonomous body under the Ministry of Health and Family Welfare (India), Government of India, and established in 1975 at New Delhi as a Society under Delhi Society registration act, to standardizing pos ...
and
Maharashtra University of Health Sciences Maharashtra University of Health Sciences (MUHS) is a higher education institution in Nashik, Maharashtra, India. History The university was established on 3 June 1998 by the state overnment of Maharashtrathrough an ordinance. The State Legis ...
. Every year about 80 post-graduate students register with the centre for doing their Master's or
Doctorate A doctorate (from Latin ''docere'', "to teach"), doctor's degree (from Latin ''doctor'', "teacher"), or doctoral degree is an academic degree awarded by universities and some other educational institutions, derived from the ancient formalism ''l ...
courses. There are about 400 students undergoing training every year in medical and non-medical fields in long and short term courses.


Digital Library

The Library of the Tata Memorial Hospital has been maintained since the inception of the hospital. It was relocated on 17 November 2000, on the ground floor of the main building now known as Digital Library. It caters to the needs of
clinicians A clinician is a health care professional typically employed at a skilled nursing facility or clinic. Clinicians work directly with patients rather than in a laboratory or as a researcher. A clinician may diagnose, treat, and otherwise care for pat ...
,
nurses Nursing is a profession within the health care sector focused on the care of individuals, families, and communities so they may attain, maintain, or recover optimal health and quality of life. Nurses may be differentiated from other health c ...
, other
paramedic A paramedic is a registered healthcare professional who works autonomously across a range of health and care settings and may specialise in clinical practice, as well as in education, leadership, and research. Not all ambulance personnel are p ...
al staff, medical administrators, and visitors from other hospitals, health care industries, academic institutions from all over the country.



Konark Cancer Foundation

Set up by the
Neurosurgeon Neurosurgery or neurological surgery, known in common parlance as brain surgery, is the medical specialty concerned with the surgical treatment of disorders which affect any portion of the nervous system including the brain, spinal cord and peri ...
, B. K. Misra,
Cardiac surgeon Cardiac surgery, or cardiovascular surgery, is surgery on the heart or great vessels performed by cardiac surgeons. It is often used to treat complications of ischemic heart disease (for example, with coronary artery bypass grafting); to corr ...
, Ramakanta Panda and former
Police Commissioner of Mumbai The Police Commissioner of Mumbai is the chief of the Mumbai Police, and an officer of the Indian Police Service. The Mumbai Police Commissioner is appointed by the Maharashtra State Government on the recommendation by the Establishment Boar ...
, Arup Patnaik,
Konark Cancer Foundation
is an NGO for patients coming to the Tata Memorial Hospital for treatment, providing them with financial support of up to INR 1 lac per patient, logistical support such as finding food and shelter for their attendants, providing other voluntary support, collecting and donating blood, medications and prosthesis. Around 10,000 patients and their families have been benefited since its inception.


References


External links


Official website


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