Stanford Moore (September 4, 1913 – August 23, 1982) was an American
biochemist
Biochemists are scientists who are trained in biochemistry. They study chemical processes and chemical transformations in living organisms. Biochemists study DNA, proteins and Cell (biology), cell parts. The word "biochemist" is a portmanteau of ...
. He shared a
Nobel Prize in Chemistry in 1972, with
Christian B. Anfinsen and
William Howard Stein, for work done at
Rockefeller University
The Rockefeller University is a Private university, private Medical research, biomedical Research university, research and graduate-only university in New York City, New York. It focuses primarily on the biological and medical sciences and pro ...
on the structure of the enzyme
ribonuclease and for contributing to the understanding of the connection between the
chemical structure
A chemical structure of a molecule is a spatial arrangement of its atoms and their chemical bonds. Its determination includes a chemist's specifying the molecular geometry and, when feasible and necessary, the electronic structure of the target m ...
and
catalytic activity of the ribonuclease molecule.
Moore attended
Peabody Demonstration School, now known as University School of Nashville, and in 1935 graduated
summa cum laude from
Vanderbilt University
Vanderbilt University (informally Vandy or VU) is a private university, private research university in Nashville, Tennessee, United States. Founded in 1873, it was named in honor of shipping and railroad magnate Cornelius Vanderbilt, who provide ...
, where he was a member of
Phi Kappa Sigma. He earned his doctorate in Organic Chemistry from the
University of Wisconsin–Madison
The University of Wisconsin–Madison (University of Wisconsin, Wisconsin, UW, UW–Madison, or simply Madison) is a public land-grant research university in Madison, Wisconsin, United States. It was founded in 1848 when Wisconsin achieved st ...
in 1938. Moore then joined the staff of the Rockefeller Institute, later Rockefeller University, where he spent his entire professional career, with the exception of a period of government service during World War II. He became Professor of Biochemistry in 1952.
In 1958, he and
William H. Stein developed the first automated amino acid analyzer, which facilitated the determination of
protein sequences. In 1959, Moore and Stein announced the first determination of the complete amino acid sequence of an enzyme, ribonuclease, work which was cited in the Nobel award.
References
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External links
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* including the Nobel Lecture, December 11, 1972 ''The Chemical Structures of Pancreatic Ribonuclease and Deoxyribonuclease''
{{DEFAULTSORT:Moore, Stanford
1913 births
1982 deaths
20th-century American biochemists
American Nobel laureates
Members of the United States National Academy of Sciences
Nobel laureates in Chemistry
University School of Nashville alumni
University of Wisconsin–Madison alumni
Vanderbilt University alumni
Rockefeller University faculty