Stand Up to Cancer (SU2C) is a charitable program of the

Entertainment Industry Foundation The Entertainment Industry Foundation (EIF), based in Los Angeles, United States, is a 501(c)(3) non-profit charitable organization of the entertainment industry. EIF funds more than 300 charitable organizations annually, both in the Los Angeles ...

(EIF). SU2C aims to raise significant funds for translational cancer research through online and televised efforts. Central to the program is a telethon that was first televised by four major broadcast networks ( ABC,

NBC The National Broadcasting Company (NBC) is an American English-language commercial broadcast television and radio network. The flagship property of the NBC Entertainment division of NBCUniversal, a division of Comcast, its headquarters are l ...

CBS CBS Broadcasting Inc., commonly shortened to CBS, the abbreviation of its former legal name Columbia Broadcasting System, is an American commercial broadcast television and radio network serving as the flagship property of the CBS Entertainm ...

, Fox) in over 170 countries on September 5, 2008. SU2C raised over $100 million after that evening's broadcast. Funds collected by Stand Up to Cancer are then distributed by the American Association for Cancer Research.

History

Stand Up to Cancer was conceived of in autumn 2007, by a group of women who had been affected by cancer and believe that by merging the recourse of the media and entertainment industries into a single operation they would be able to fight against this disease in a more profound way. Stand Up to Cancer was formally launched on May 27, 2008. Current members of the SU2C Council of Founders and Advisors (CFA) include

Katie Couric Katherine Anne Couric ( ; born January 7, 1957) is an American journalist and presenter. She is founder of Katie Couric Media, a multimedia news and production company. She also publishes a daily newsletter, ''Wake Up Call''. From 2013 to 2017, ...

Sherry Lansing Sherry Lansing (born Sherry Lee Duhl; July 31, 1944) is an American philanthropist and retired film studio executive. She is a former CEO of Paramount Pictures and president of production at 20th Century Fox. In 1996, she became the first woman ...

, Kathleen Lobb, Lisa Paulsen, Rusty Robertson, Sue Schwartz, Pamela Oas Williams, and Ellen Ziffren. All current members of the CFA were co-producers of the 2012 televised special. The late co-founder Laura Ziskin executive produced both the September 5, 2008 and September 10, 2010 broadcasts. Sung Poblete, Ph.D., R.N., has served as SU2C’s president and CEO since 2011. In the United Kingdom,

Channel 4 Channel 4 is a British free-to-air public broadcast television network operated by the state-owned Channel Four Television Corporation. It began its transmission on 2 November 1982 and was established to provide a fourth television service ...

, along with

Cancer Research UK Cancer Research UK (CRUK) is the world's largest independent cancer research organization. It is registered as a charity in the United Kingdom and Isle of Man, and was formed on 4 February 2002 by the merger of The Cancer Research Campaign and t ...

, launched its own version of ''

Stand Up to Cancer Stand Up to Cancer (SU2C) is a charitable program of the Entertainment Industry Foundation (EIF). SU2C aims to raise significant funds for translational cancer research through online and televised efforts. Central to the program is a telethon tha ...

'' in October 2012, which has continued every year since.

Initiative

Stand Up to Cancer aims to raise awareness and bring about an understanding that everyone is connected to cancer. The statistic used most often by SU2C is from the American Cancer Society: one out of every two men and one out of every three women will be diagnosed with cancer in their lifetime,ACS Cancer Facts and Figures 2008
Retrieved on 27 May 2008. meaning everyone is affected in some way, or will be. The campaign has featured televised moments during

World Series The World Series is the annual championship series of Major League Baseball (MLB) in the United States and Canada, contested since 1903 between the champion teams of the American League (AL) and the National League (NL). The winner of the World ...

baseball games where fans literally "stand up to cancer" by rising and holding signs inscribed with the names of friends and loved ones who have struggled with the disease. File:Fans Stand Up To Cancer (22808003366).jpg, Fans pay tribute by standing with signs during game 3 of the

2015 World Series The 2015 World Series was the championship series of Major League Baseball's (MLB) 2015 season. The 111th edition of the World Series, it was a best-of-seven playoff between the National League (NL) champion New York Mets and the American Leag ...

File:Standing Up to Cancer during the All-Star Game (27805716023).jpg, Fans pay tribute by standing with signs at the

2016 Major League Baseball All-Star Game The 2016 Major League Baseball All-Star Game was the 87th edition of the Major League Baseball All-Star Game. The game was hosted by the San Diego Padres and was played at Petco Park on July 12, 2016. It was televised nationally on Fox. The Ame ...

File:Stand Up to Cancer IMG 5426 2016-WS-G4 (cropped1).jpg, Fans participate by rising and holding signs at game 4 of the

2016 World Series The 2016 World Series was the championship series of Major League Baseball's (MLB) 2016 season. The 112th edition of the World Series, it was a best-of-seven playoff between the National League (NL) champion Chicago Cubs and the American Leag ...

Research teams funded

SU2C has donated hundreds of millions of dollars since the first "Dream Team" was organized in 2009. The "Dream Teams" funded by SU2C brings researchers together from institutions and universities across the world and have been among the most productive collaborations in getting new drugs to market and many teams are funded jointly with other cancer research organizations. The research is required to be translational and include laboratory and clinical members and cannot involve more than one principal investigator from each institution. Many of these dream teams are co-sponsored by other cancer-related foundations. * SU2C-CRUK- Lustgarten Foundation Pancreatic Cancer Dream Team: Reprogramming of Transcriptional Circuitry to Control Pancreatic Cancer ($12 million) :: Led by Daniel Von Hoff,

Ronald M. Evans Ronald Mark Evans (born April 17, 1949 in Los Angeles, California) is an American Biologist, Professor and Head of the Salk’s Gene Expression Laboratory, and the March of Dimes Chair in Molecular and Developmental Biology at the Salk Institute fo ...

Gerard Evan Gerard Ian Evan FRS, FMedSci (born 17 August 1955) is a British biologist and, since May 2022, Professor of Cancer Biology at King's College London and a principal group leader in the Francis Crick Institute. Prior to this he was Sir William ...

* Stand Up to Cancer (SU2C)-

Dutch Cancer Society The Dutch Cancer Society (DCS; in Dutch: '' 'KWF Kankerbestrijding' '') is a Dutch Society committed to fight cancer by scientific research, education, patient support and fundraising in cooperation with volunteers, donors, patients, doctors and res ...

Dream Team: Molecular Early Detection of Colorectal Cancer (MEDOCC) :: Led by Gerrit A. Meijer,

Victor Velculescu Victor E. Velculescu (born August 16, 1970) is a Professor of Oncology and Co-Director of Cancer Biology at Johns Hopkins University School of Medicine. He is internationally known for his discoveries in genomics and cancer research. Early lif ...

* SU2C-

Ovarian Cancer Research Fund Alliance The ovary is an organ in the female reproductive system that produces an ovum. When released, this travels down the fallopian tube into the uterus, where it may become fertilized by a sperm. There is an ovary () found on each side of the body. T ...

National Ovarian Cancer Coalition National may refer to: Common uses * Nation or country ** Nationality – a ''national'' is a person who is subject to a nation, regardless of whether the person has full rights as a citizen Places in the United States * National, Maryland, c ...

Dream Team: DNA Repair Therapies for Ovarian Cancer :: Led by

Alan D’Andrea Alan may refer to: People *Alan (surname), an English and Turkish surname *Alan (given name), an English given name **List of people with given name Alan ''Following are people commonly referred to solely by "Alan" or by a homonymous name.'' * A ...

Elizabeth Swisher Elizabeth or Elisabeth may refer to: People * Elizabeth (given name), a female given name (including people with that name) * Elizabeth (biblical figure), mother of John the Baptist Ships * HMS ''Elizabeth'', several ships * ''Elisabeth'' (sch ...

* The SU2C- ACS Lung Cancer Dream Team: Targeting KRAS Mutant Lung Cancers :: Led by

Jeffrey Engelman Jeffrey may refer to: * Jeffrey (name), including a list of people with the name * ''Jeffrey'' (1995 film), a 1995 film by Paul Rudnick, based on Rudnick's play of the same name * ''Jeffrey'' (2016 film), a 2016 Dominican Republic documentary film ...

, Jedd D. Wolchok * Tumor Organoids: A New Preclinical Model for Drug Sensitivity Analysis :: Led by

Hans Clevers Johannes (Hans) Carolus Clevers (born 27 March 1957) is a Dutch molecular geneticist, cell biologist and stem cell researcher. He became the Head of Pharma, Research and Early Development, and a member of the Corporate Executive Committee, of ...

, Hans Bos * The SU2C-The Lustgarten Foundation Pancreatic Cancer Convergence Dream Team: Transforming Pancreatic Cancer to Treatable Disease :: Led by Elizabeth M. Jaffee, Robert H. Vonderheide * SU2C- St. Baldrick’s Pediatric Cancer Dream Team: Immunogenomics to Create New Therapies for High-Risk Childhood Cancers :: Led by John M. Maris, Crystal L. Mackall * SU2C-CRI Dream Team: Immunologic Checkpoint Blockade and Adoptive Cell Transfer in Cancer Therapy :: Led by

James P. Allison James Patrick Allison (born August 7, 1948) is an American immunologist and Nobel laureate who holds the position of professor and chair of immunology and executive director of immunotherapy platform at the MD Anderson Cancer Center at the Uni ...

, Antoni Ribas, Drew Pardoll, Cassian Yee * SU2C-PCF2 Dream Team: Targeting Adaptive Pathways in Metastatic Treatment-Resistant Prostate Cancer :: Led by Eric J. Small, Owen Witte * SU2C-PCF Dream Team: Precision Therapy for Advanced Prostate Cancer :: Led by

Arul Chinnaiyan Arul M. Chinnaiyan is a Hicks Endowed Professor of Pathology and professor of pathology and urology at the University of Michigan Medical School. He is also a Howard Hughes medical Investigator (HHMI) at the Howard Hughes Medical Institute. Ar ...

, Charles L. Sawyers * SU2C-MRA Dream Team: Personalized Medicine for Patients with BRAF Wild-Type Cancer :: Led by Jeffrey Trent, Patricia M. LoRusso * An Integrated Approach to Targeting Breast Cancer Molecular Subtypes and their Resistance Phenotype :: Led by Joe W. Gray, Dennis Slamon * The

VARI Vari ( el, Βάρη) is a southern suburb of Athens and former municipality in East Attica, Greece along the Athens coast. Since the 2011 local government reform it is part of the municipality Vari-Voula-Vouliagmeni, of which it is a municipal u ...

-SU2C Epigenetics Dream Team ll :: Led by Peter A. Jones, Stephen B. Baylin * Bioengineering and Clinical Applications of Circulating Tumor Cell Chip :: Led by Daniel Haber, Mehmet Toner * Cutting off the Fuel Supply: A New Approach to the Treatment of Pancreatic Cancer ($22 million) :: Led by Craig B. Thompson, Daniel Von Hoff * Targeting PI3K in Women’s Cancers :: Led by Gordon B. Mills, Lewis C. Cantley * SU2C-Lustgarten Foundation Chimeric Antigen Receptor T Cell (CAR-T) Translational Research Team :: Led by Carl June, E. John Wherry, Shelley L. Berger * SU2C Colorectal Cancer Dream Team: Targeting Genomic, Metabolic and Immunological Vulnerabilities of Colorectal Cancer :: Led by Charles S. Fuchs, Zhenghe Wang, Lewis C. Cantley, Luis A. Diaz Jr Research led by these teams has contributed to the development of two FDA-approved treatments;

palbociclib Palbociclib, sold under the brand name Ibrance among others, is a medication developed by Pfizer for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Pa ...

(Breast Cancer Dream Team), and abraxane plus

gemcitabine Gemcitabine, with brand names including Gemzar, is a chemotherapy medication. It treats cancers including testicular cancer, breast cancer, ovarian cancer, non-small cell lung cancer, pancreatic cancer, and bladder cancer. It is administered by ...

(Pancreatic Cancer Dream Team).

United States

Joe Biden speaking at Stand Up to Cancer fundraiser 2016

Six telethons have been broadcast in the United States and are made available to more than 190 countries. To date, more than $603 million has been pledged to support SU2C’s innovative cancer research programs. The first Stand Up to Cancer event was held on September 5, 2008, raising over $100 million. The second was held on 10 September 2010. The third was held on 7 September 2012, and the fourth was held on 5 September 2014, presented by Gwyneth Paltrow and

from Los Angeles. The fifth was held on 9 September 2016. The averaged combined ratings for the 2014 telethon were 1.8 from 2.1 in 2012. The sixth was broadcast on 7 September 2018, raising more than $123 million. This event was aired on more than 70 broadcast and cable networks and streaming and social platforms, including: CBS, HBO and NBC. In Canada, the 2014 telethon aired September 5, 2014 in

simultaneous substitution Simultaneous substitution (also known as simsubbing or signal substitution) is a practice mandated by the Canadian Radio-television and Telecommunications Commission (CRTC) requiring broadcast distribution undertakings (BDUs) in Canada to dis ...

(in many areas) with the American telethon, simultaneously on English language networks CBC Television,

City A city is a human settlement of notable size.Goodall, B. (1987) ''The Penguin Dictionary of Human Geography''. London: Penguin.Kuper, A. and Kuper, J., eds (1996) ''The Social Science Encyclopedia''. 2nd edition. London: Routledge. It can be def ...

, CTV and

Global Global means of or referring to a globe and may also refer to: Entertainment * ''Global'' (Paul van Dyk album), 2003 * ''Global'' (Bunji Garlin album), 2007 * ''Global'' (Humanoid album), 1989 * ''Global'' (Todd Rundgren album), 2015 * Bruno ...

, as well as

CHCH-DT CHCH-DT (channel 11) is an independent television station in Hamilton, Ontario, Canada. Owned by Channel Zero, the station maintains studios on Innovation Drive in the west end of Hamilton; prior to 2021, it was located near the corner of Jack ...

Hamilton, Ontario Hamilton is a port city in the Canadian Provinces and territories of Canada, province of Ontario. Hamilton has a Canada 2016 Census, population of 569,353, and its Census Metropolitan Area, census metropolitan area, which includes Burlington, ...

CHEK-DT CHEK-DT (channel 6) is an independent television station in Victoria, British Columbia, Canada, serving Vancouver Island and Greater Vancouver. The station is owned by the CHEK Media Group, a consortium made up of station employees and local inv ...

Victoria, British Columbia Victoria is the capital city of the Canadian province of British Columbia, on the southern tip of Vancouver Island off Canada's Pacific coast. The city has a population of 91,867, and the Greater Victoria area has a population of 397,237. The ...

CJON-DT CJON-DT (channel 21), branded on-air as NTV (short for Newfoundland Television), is an English-language independent television station in St. John's, Newfoundland and Labrador, Canada, owned by Newfoundland Broadcasting Company Ltd. The statio ...

in St. John's, Newfoundland and Labrador, and specialty channels TLN,

Fight Network Fight Network is a Canadian English language Category B specialty channel owned by Anthem Sports & Entertainment. The network broadcasts programming related to combat sports, including mixed martial arts, boxing, kickboxing, and professional wre ...

Gusto TV CTV Life Channel is a Canadian English language specialty channel owned by Bell Media. The channel primarily broadcasts factual and reality programming on lifestyle topics such as cooking, home improvement and real estate, along with scripted dram ...

AMI-TV AMI-tv is a Canadian, English-language, digital cable specialty channel owned by the non-profit organization Accessible Media. AMI-tv broadcasts a selection of general entertainment programming with accommodations for those who are visually or h ...

and the Hollywood Suite channels. The Canadian broadcast of the telethon benefits EIF Canada, the Canadian arm of the Entertainment Industry Foundation, with all donations benefiting cancer research in Canada. It was not held in the fall of 2020 due to the

COVID-19 pandemic The COVID-19 pandemic, also known as the coronavirus pandemic, is an ongoing global pandemic of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The novel virus was first identi ...

, but postponed to August 21, 2021.

United Kingdom

On 19 October 2012,

in the

United Kingdom The United Kingdom of Great Britain and Northern Ireland, commonly known as the United Kingdom (UK) or Britain, is a country in Europe, off the north-western coast of the European mainland, continental mainland. It comprises England, Scotlan ...

aired their first telethon for Stand Up to Cancer hosted by

Davina McCall Davina Lucy Pascale McCall (born 16 October 1967) is an English television presenter. She was the presenter of the reality show '' Big Brother'' during its run on Channel 4 between 2000 and 2010. She also hosted Channel 4's ''Streetmate'' (199 ...

and

Alan Carr Alan Graham Carr (born 14 June 1976) is an English comedian, broadcaster and writer. His breakthrough was in 2001, winning the '' City Life'' Best Newcomer of the Year and the BBC New Comedy Awards. In the ensuing years, Carr's career burgeon ...

along with Dr. Christian Jessen. A second telethon was broadcast on 17 October 2014, again hosted by McCall and Carr along with Dr. Jessen. Subsequent UK telethons, again on Channel 4, followed in 2016 and 2018. Stand Up to Cancer's fundraising activities in the UK include the London 3 Peaks Challenge, which involves participants running up the stairs of Heron Tower,

30 St Mary Axe 30 St Mary Axe (previously known as the Swiss Re Building and informally known as the Gherkin) is a commercial skyscraper in London's primary financial district, the City of London. It was completed in December 2003 and opened in April 2004. ...

and

200 Aldersgate 200 Aldersgate is a 434,005 sq ft office building in the City of London. Proposed in 1983, designed by the architects Fitzroy Robinson & Partners, and built in 1991–92, the building was the headquarters of legal firm Clifford Chance before it ...

before

abseiling Abseiling ( ; ), also known as rappelling ( ; ), is the controlled descent of a steep slope, such as a rock face, by moving down a rope. When abseiling the person descending controls their own movement down the rope, in contrast to low ...

down the outside of

. Despite the Original American version cancelling their telethon and ITV giving up on their '' Text Santa'' shows, Channel 4 have still scheduled a telethon over the last two years, in addition to a number of other charity celebrity specials on the network. The most recent one was held on 15 October 2021, and was hosted by Alan Carr, Adam Hills, Maya Jama and Davina McCall. In addition to this, Channel 4 will be bringing back a version of the

British Comedy Awards The National Comedy Awards (known as the British Comedy Awards from 1990 to 2014) is an annual awards ceremony in the United Kingdom, celebrating notable comedians and entertainment performances of the previous year. The British Comedy Awards (1 ...

for Stand Up to Cancer, with the renamed National Comedy Awards due to be held in London on 15 December 2021.Home - National Comedy Awards
/ref>

References

External links

Stand Up to Cancer website

Stand Up to Cancer Canada website
{{DEFAULTSORT:Stand Up to Cancer Cancer fundraisers Charities based in Canada Cancer charities in the United States Charities based in California 2008 television specials Online magazines published in Canada Magazines established in 2008 International broadcasting Simulcasts Annual events in the United States American annual television specials Annual television shows 2008 American television series debuts Cancer organizations based in Canada 2014 television specials Television Academy Honors winners