Simon LeVay
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Simon LeVay (born 28 August 1943 in
Oxford Oxford () is a city in England. It is the county town and only city of Oxfordshire. In 2020, its population was estimated at 151,584. It is north-west of London, south-east of Birmingham and north-east of Bristol. The city is home to the ...
, England) is a British-American
neuroscientist A neuroscientist (or neurobiologist) is a scientist who has specialised knowledge in neuroscience, a branch of biology that deals with the physiology, biochemistry, psychology, anatomy and molecular biology of neurons, neural circuits, and glial ...
. He received a bachelor's degree in natural sciences from the
University of Cambridge The University of Cambridge is a public collegiate research university in Cambridge, England. Founded in 1209 and granted a royal charter by Henry III in 1231, Cambridge is the world's third oldest surviving university and one of its most pr ...
in 1966, a Ph.D. in
Neuroanatomy Neuroanatomy is the study of the structure and organization of the nervous system. In contrast to animals with radial symmetry, whose nervous system consists of a distributed network of cells, animals with bilateral symmetry have segregated, defi ...
at the
University of Göttingen The University of Göttingen, officially the Georg August University of Göttingen, (german: Georg-August-Universität Göttingen, known informally as Georgia Augusta) is a public research university in the city of Göttingen, Germany. Founded ...
in
Germany Germany,, officially the Federal Republic of Germany, is a country in Central Europe. It is the second most populous country in Europe after Russia, and the most populous member state of the European Union. Germany is situated betwe ...
, and completed his post doctoral fellowship at
Harvard Medical School Harvard Medical School (HMS) is the graduate medical school of Harvard University and is located in the Longwood Medical Area of Boston, Massachusetts. Founded in 1782, HMS is one of the oldest medical schools in the United States and is consi ...
in 1974. LeVay held positions in
neurobiology Neuroscience is the scientific study of the nervous system (the brain, spinal cord, and peripheral nervous system), its functions and disorders. It is a multidisciplinary science that combines physiology, anatomy, molecular biology, developme ...
at the Harvard Medical School from 1974 to 1984. He then worked at the Salk Institute for Biological Studies from 1984 to 1993 while holding an Associate Professorship in Biology at the
University of California, San Diego The University of California, San Diego (UC San Diego or colloquially, UCSD) is a public land-grant research university in San Diego, California. Established in 1960 near the pre-existing Scripps Institution of Oceanography, UC San Diego is t ...
. Much of his early work focused on the
visual cortex The visual cortex of the brain is the area of the cerebral cortex that processes visual information. It is located in the occipital lobe. Sensory input originating from the eyes travels through the lateral geniculate nucleus in the thalamus and ...
in animals. While working at the Salk Institute for Biological Studies, LeVay published an article in
Science Science is a systematic endeavor that Scientific method, builds and organizes knowledge in the form of Testability, testable explanations and predictions about the universe. Science may be as old as the human species, and some of the earli ...
that compared the size of the "
Interstitial An interstitial space or interstice is a space between structures or objects. In particular, interstitial may refer to: Biology * Interstitial cell tumor * Interstitial cell, any cell that lies between other cells * Interstitial collagenase ...
Nucleus of the Anterior
Hypothalamus The hypothalamus () is a part of the brain that contains a number of small nuclei with a variety of functions. One of the most important functions is to link the nervous system to the endocrine system via the pituitary gland. The hypothalamu ...
" ( INAH3) in a group of gay men to a group of straight men and women. This was the first scientific study ever published that showed brain differences based on
sexual orientation Sexual orientation is an enduring pattern of romantic or sexual attraction (or a combination of these) to persons of the opposite sex or gender, the same sex or gender, or to both sexes or more than one gender. These attractions are generall ...
. The study results were featured on
PBS The Public Broadcasting Service (PBS) is an American public broadcaster and non-commercial, free-to-air television network based in Arlington, Virginia. PBS is a publicly funded nonprofit organization and the most prominent provider of educat ...
,
Newsweek ''Newsweek'' is an American weekly online news magazine co-owned 50 percent each by Dev Pragad, its president and CEO, and Johnathan Davis, who has no operational role at ''Newsweek''. Founded as a weekly print magazine in 1933, it was widely ...
, Nightline, Donahue, and
The Oprah Winfrey Show ''The Oprah Winfrey Show'', often referred to as ''The Oprah Show'' or simply ''Oprah'', is an American daytime syndicated talk show that aired nationally for 25 seasons from September 8, 1986, to May 25, 2011, in Chicago, Illinois. Produced ...
. In 1992, he took a leave of absence from Salk to help form the Institute of Gay and Lesbian Education (IGLE) in
West Hollywood West Hollywood is a city in Los Angeles County, California, United States. Incorporated in 1984, it is home to the Sunset Strip. As of the 2020 U.S. Census, its population was 35,757. It is considered one of the most prominent gay villages ...
with Chris Patrouch and Lauren Jardine. He never returned. LeVay has spoken extensively on the topic of human sexuality at a number of venues and publish a number of books. In 2003 he became a lecturer in Human Sexuality Studies at Stanford University.


Personal life

Simon LeVay was born on 28 August 1943 in Oxford, England. LeVay spent most of his childhood in
West Dulwich West Dulwich ( ) is a neighbourhood in South London on the southern boundary of Brockwell Park, which straddles the London Borough of Lambeth and the London Borough of Southwark. Croxted Road and South Croxted Road mark the boundary between S ...
where he attended Dulwich Preparatory School. LeVay went on to attend
Dulwich College Dulwich College is a 2–19 Independent school (United Kingdom), independent, Day school, day and boarding school for Single-sex education, boys in Dulwich, London, England. As a Public school (United Kingdom), public school, it began as the Col ...
where he specialized in Latin, Greek, and Ancient History while excelling in cycling. It was at Dulwich College where LeVay also admitted to himself that he was gay.


Education

Before moving on to higher education, LeVay spent a gap year in
Göttingen Göttingen (, , ; nds, Chöttingen) is a university city in Lower Saxony, central Germany, the capital of the eponymous district. The River Leine runs through it. At the end of 2019, the population was 118,911. General information The ori ...
Germany where he worked as a technician in an electron microscope lab, learned German, and published a scientific article on the spinal cord of chickens. When the gap year was complete, LeVay returned to England, where he was admitted into Cambridge University. After graduating with a B.A. in natural sciences, he continued the clinical portion of his medical education at the
University College Hospital University College Hospital (UCH) is a teaching hospital in the Fitzrovia area of the London Borough of Camden, England. The hospital, which was founded as the North London Hospital in 1834, is closely associated with University College Lond ...
in
London London is the capital and List of urban areas in the United Kingdom, largest city of England and the United Kingdom, with a population of just under 9 million. It stands on the River Thames in south-east England at the head of a estuary dow ...
before dropping out of medical school altogether. LeVay returned to the lab in Göttingen and enrolled in graduate school, where he published his doctoral thesis on the visual system before graduating with a Ph.D. in neuroanatomy in 1971. At the University of Göttingen, LeVay met an American exchange student from the
University of California, Berkeley The University of California, Berkeley (UC Berkeley, Berkeley, Cal, or California) is a public land-grant research university in Berkeley, California. Established in 1868 as the University of California, it is the state's first land-grant u ...
named Richard Hersey and fell in love. When Hersey left Germany and returned to the
United States The United States of America (U.S.A. or USA), commonly known as the United States (U.S. or US) or America, is a country primarily located in North America. It consists of 50 states, a federal district, five major unincorporated territori ...
, LeVay followed him and began looking at postdoctoral positions in
Boston Boston (), officially the City of Boston, is the state capital and most populous city of the Commonwealth of Massachusetts, as well as the cultural and financial center of the New England region of the United States. It is the 24th- mo ...
, New York, and
Wisconsin Wisconsin () is a state in the upper Midwestern United States. Wisconsin is the 25th-largest state by total area and the 20th-most populous. It is bordered by Minnesota to the west, Iowa to the southwest, Illinois to the south, Lake M ...
. He eventually got a job at
Harvard Medical School Harvard Medical School (HMS) is the graduate medical school of Harvard University and is located in the Longwood Medical Area of Boston, Massachusetts. Founded in 1782, HMS is one of the oldest medical schools in the United States and is consi ...
working in the lab of
David Hubel David Hunter Hubel (February 27, 1926 – September 22, 2013) was a Canadian American neurophysiologist noted for his studies of the structure and function of the visual cortex. He was co-recipient with Torsten Wiesel of the 1981 Nobel Priz ...
and
Torsten Wiesel Torsten Nils Wiesel (born 3 June 1924) is a Swedish neurophysiologist. With David H. Hubel, he received the 1981 Nobel Prize in Physiology or Medicine, for their discoveries concerning information processing in the visual system; the prize was ...
. LeVay and Hersey spent a year traveling in the United States before Hersey returned to Berkeley, and LeVay started his life in
Boston Boston (), officially the City of Boston, is the state capital and most populous city of the Commonwealth of Massachusetts, as well as the cultural and financial center of the New England region of the United States. It is the 24th- mo ...
.


Career

LeVay completed his postdoc at Harvard Medical School and began teaching in the Neurobiology Department. In 1984, LeVay accepted a job at the Salk Institute in
San Diego San Diego ( , ; ) is a city on the Pacific Ocean coast of Southern California located immediately adjacent to the Mexico–United States border. With a 2020 population of 1,386,932, it is the eighth most populous city in the United State ...
,
California California is a state in the Western United States, located along the Pacific Coast. With nearly 39.2million residents across a total area of approximately , it is the most populous U.S. state and the 3rd largest by area. It is also the m ...
where he studied the brain's role in vision. He also began working as an Associate Professor in
Biology Biology is the scientific study of life. It is a natural science with a broad scope but has several unifying themes that tie it together as a single, coherent field. For instance, all organisms are made up of cells that process hereditary i ...
at the University of California. LeVay took a leave of absence to take care of Hersey, who had contracted AIDS. After Hersey died of the disease in 1990, LeVay returned to Salk with little interest in continuing his work on the visual centers of the brain. "Richard and I had spent 21 years together," LeVay said during an interview with a reporter from Discover Magazine. "It was while looking after him that I decided I wanted to do something different with my life...I had an emotional need to do something more personal, something connected with my gay identity." In 1991, LeVay published an article in Science that compared a structure in the hypothalamus called INAH3 in the brains of male homosexuals to that found in a group of heterosexual men and heterosexual women. He found that this region of the brain in gay men was similar to that found in straight women. This was the first scientific study that found a difference between groups of people based on sexual orientation. In 1992, LeVay took a second leave of absence from Salk to help form the Institute of Gay and Lesbian Education (IGLE) in West Hollywood with Chris Patrouch and Lauren Jardine. He never returned. After IGLE folded, LeVay would go on to speak on the topic of
human sexuality Human sexuality is the way people experience and express themselves sexually. This involves biological, psychological, physical, erotic, emotional, social, or spiritual feelings and behaviors. Because it is a broad term, which has varied ...
at a number of venues and publish 12 books. In 2003 he became a lecturer in Human Sexuality Studies at Stanford University.


INAH3 research

Researchers had been comparing the brains of men and women since the 1980s, but the article that caught LeVay's attention was published by a group at UCLA. In the study, the researchers compared the hypothalami of 11 men to 11 women. Of particular interest to LeVay was an area the researchers called the "Interstitial Nucleus of the Anterior Hypothalamus" ( INAH3), a part of the brain that had been found to help regulate sexual behavior. The UCLA team found that INAH3 was, on average, twice as large in men as it was in women. This made LeVay wonder if he would see differences in this grouping of cells based on sexual orientation as well. "I was already working on structure and function in one part of the brain, so working on the sexual part of the brain wasn't a big switch." Over a period of nine months, LeVay performed surgery on the brains of 41 cadavers: 18 gay men (plus 1 bisexual male), 16 straight men, and 6 straight women. To ensure that the process was fully blinded, he'd had each brain numerically encoded to conceal the sexual orientations of each donor. In 1991, LeVay published "A difference in hypothalamic structure between heterosexual and homosexual men" in ''
Science Science is a systematic endeavor that Scientific method, builds and organizes knowledge in the form of Testability, testable explanations and predictions about the universe. Science may be as old as the human species, and some of the earli ...
''. On average, LeVay found that the INAH3 in the brains of heterosexual men were more than twice as large as that found in the homosexuals. In fact, the INAH3 size of the homosexual group was the same size as the women. LeVay wrote that "This finding indicates that INAH is dimorphic with sexual orientation, at least in men, and suggests that sexual orientation has a biological substrate." This was the first scientific study that looked specifically at differences between brains on the basis of sexual orientation. Because of this, LeVay's finding attracted a lot of media attention. The study results were featured on PBS, Newsweek, Nightline, Donahue, and The Oprah Winfrey Show. The results received push back from some religious groups as well as from members of the LGBT community. There were also several criticisms from scientists: *The AIDS virus can attack the central nervous system, and nearly all of the gay men in LeVay's study had died of AIDS. What effect, if any, did
HIV The human immunodeficiency viruses (HIV) are two species of ''Lentivirus'' (a subgroup of retrovirus) that infect humans. Over time, they cause acquired immunodeficiency syndrome (AIDS), a condition in which progressive failure of the immune ...
have on this region of the brain? Were the perceived differences the result of biology or because of HIV's actions on the brain? *LeVay's study only considered 41 brain samples. Too few data points can make study results unreliable. *In straight males, LeVay found that the INAH3 structure was about the size of a grain of sand. In women (and in gay men), it was almost non-existent. Because of the extremely small size, these structures could be difficult to precisely measure in tissue slices. *LeVay's data showed a range of size values for INAH3 in both the homosexual and heterosexual brains. Some of the gay men had larger INAH3 structures, some of the straight men had smaller structures, and the numbers overlapped. Anne Fausto-Sterling at Brown University said, "If LeVay picked a nucleus size in the middle, he couldn't tell if it was heterosexual or homosexual." *The brain influences the way the person acts, but the environment can influence brain structures. There was not enough information about the people in the study to know whether the results were biological in nature, or whether the behavior of the gay participants caused that region of the brain to change over time. LeVay himself cautioned against misinterpreting his findings: "I did not prove that homosexuality is genetic, or find a genetic cause for being gay. I didn't show that gay men are born that way, the most common mistake people make in interpreting my work. Nor did I locate a gay center in the brain." In an interview with
Newsweek ''Newsweek'' is an American weekly online news magazine co-owned 50 percent each by Dev Pragad, its president and CEO, and Johnathan Davis, who has no operational role at ''Newsweek''. Founded as a weekly print magazine in 1933, it was widely ...
in 1992, he said, "What I reported was a difference in the brain structure of the hypothalamus. We can't say on the basis of that what makes people gay or straight. But it opens the door to find the answer to that question."


Institute of Gay and Lesbian Education

After Governor
Pete Wilson Peter Barton Wilson (born August 23, 1933) is an American attorney and politician who served as the 36th governor of California from 1991 to 1999. A member of the Republican Party, he also served as a United States senator from California betw ...
vetoed California Bill AB101 which would have extended civil rights protections to the LGBT community, LeVay became active in the community. While attending a gay political group, he met a planner in West Hollywood by the name of Chris Patrouch. In their conversations Patrouch pitched the idea of creating a new educational institution in West Hollywood that would be gay friendly. LeVay liked the idea so much that he took a leave of absence from Salk in 1992 to help. They were planning to call the institution the "
Harvey Milk Harvey Bernard Milk (May 22, 1930 – November 27, 1978) was an American politician and the first openly gay man to be elected to public office in California, as a member of the San Francisco Board of Supervisors. Milk was born and raised in ...
University" after the first openly gay elected supervisor of
San Francisco San Francisco (; Spanish for " Saint Francis"), officially the City and County of San Francisco, is the commercial, financial, and cultural center of Northern California. The city proper is the fourth most populous in California and 17th ...
that had been assassinated by
Dan White Daniel James White (September 2, 1946 – October 21, 1985) was an American politician who assassinated San Francisco Mayor George Moscone and Supervisor Harvey Milk, on Monday, November 27, 1978, at City Hall. White was convicted of manslaugh ...
in 1987. However, they eventually formed the West Hollywood Institute of Gay and Lesbian Education (IGLE) with Lauren Jardine. The West Hollywood City Counsel unanimously passed a resolution giving IGLE free space in a building owned by the city and IGLE began offering classes in 1992. Unfortunately, IGLE did not meet enrollment expectations that first year. Boxall reports that 14 of 22 classes that had been listed in the course catalog had been canceled due to lack of enrollment. Two years later IGLE's administrators were still struggling with whether the school was going to concentrate on teaching classes focused on gay and lesbian studies, or whether it was going to focus on teaching conventional subjects to LGBT students. Patrouch and LeVay had been hoping to get their courses accredited and start offering degrees, but the situation proved untenable and IGLE shut down in 1996.


Books


The Sexual Brain

''The Sexual Brain'', published in 1993, was LeVay's first book. It discussed brain mechanisms involved in sexual behavior and feelings.


Queer Science

''Queer Science: The Use and Abuse of Research into Homosexuality'', published in 1996, was a survey of sexual orientation research. It discussed the work of pioneering sexologists such as
Karl Heinrich Ulrichs Karl Heinrich Ulrichs (28 August 1825 – 14 July 1895) was a German lawyer, jurist, journalist, and writer who is regarded today as a pioneer of sexology and the modern gay rights movement. Ulrichs has been described as the "first gay man in ...
and
Magnus Hirschfeld Magnus Hirschfeld (14 May 1868 – 14 May 1935) was a German physician and sexologist. Hirschfeld was educated in philosophy, philology and medicine. An outspoken advocate for sexual minorities, Hirschfeld founded the Scientific-Humanitarian Com ...
,
Sigmund Freud Sigmund Freud ( , ; born Sigismund Schlomo Freud; 6 May 1856 – 23 September 1939) was an Austrian neurologist and the founder of psychoanalysis, a clinical method for evaluating and treating pathologies explained as originating in conflicts ...
and his followers, behaviorism, and LeVay's own research on INAH3 and its possible implications.


Albrick's Gold

''Albrick's Gold'', published in 1997, was a
science fiction Science fiction (sometimes shortened to Sci-Fi or SF) is a genre of speculative fiction which typically deals with imaginative and futuristic concepts such as advanced science and technology, space exploration, time travel, parallel uni ...
novel, whose main character, Roger Cavendish, is partially based on Simon LeVay.


Gay, Straight, and the Reason Why

''Gay, Straight, and the Reason Why: The Science of Sexual Orientation'', first published in 2010, details findings from over 650 studies on sexual orientation, including findings he had not considered: "I didn't expect the avenue of research about birth order, that gay men tend to be late born in families, and that women aren't as fixed in their sexual orientation as are men." A second edition was released in 2016. In 2010, ''Gay, Straight, and the Reason Why'' won the Bonnie and Vern L. Bullough Award which is given by the Foundation for the Scientific Study of Sexuality to the most distinguished book written for the professional sexological community.


Other books

LeVay has also co-authored a textbook on
human sexuality Human sexuality is the way people experience and express themselves sexually. This involves biological, psychological, physical, erotic, emotional, social, or spiritual feelings and behaviors. Because it is a broad term, which has varied ...
and books on
earthquake An earthquake (also known as a quake, tremor or temblor) is the shaking of the surface of the Earth resulting from a sudden release of energy in the Earth's lithosphere that creates seismic waves. Earthquakes can range in intensity, fr ...
s,
volcano A volcano is a rupture in the Crust (geology), crust of a Planet#Planetary-mass objects, planetary-mass object, such as Earth, that allows hot lava, volcanic ash, and volcanic gas, gases to escape from a magma chamber below the surface. On Ear ...
es,
Parkinson's disease Parkinson's disease (PD), or simply Parkinson's, is a long-term degenerative disorder of the central nervous system that mainly affects the motor system. The symptoms usually emerge slowly, and as the disease worsens, non-motor symptoms becom ...
, and extraterrestrial life. ''Human Sexuality'' (now in its third edition) was described in one review as "an exceptional book that addresses nearly every aspect of sexuality from multiple theoretical, historical, and cultural perspectives."


Works

*LeVay S (1993). '' The Sexual Brain''. Cambridge: MIT Press. *LeVay S, Nonas E (1995). ''City of Friends: A Portrait of the Gay and Lesbian Community in America''. Cambridge: MIT Press. *LeVay S (1996). '' Queer Science: The Use and Abuse of Research into Homosexuality''. Cambridge: MIT Press. *LeVay S (1997). ''Albrick's Gold''. London: Headline Book Publishing. *Sieh K, LeVay, S (1998). ''The Earth in Turmoil: Earthquakes, Volcanoes, and Their Impact on Humankind''. New York: W.H. Freeman. *Koerner, D, LeVay, S (2000). ''Here Be Dragons: The Scientific Quest for Extraterrestrial Life''. Oxford: Oxford University Press. *Freed, C, LeVay, S (2002). ''Healing the Brain: A Doctor's Controversial Quest for a Cell Therapy to Cure Parkinson's Disease''. New York: Times Books. *LeVay S, (2008). ''When Science Goes Wrong'', Plume. *LeVay S, Baldwin J (Fourth ed., 2012). ''
Human Sexuality Human sexuality is the way people experience and express themselves sexually. This involves biological, psychological, physical, erotic, emotional, social, or spiritual feelings and behaviors. Because it is a broad term, which has varied ...
''. Sunderland: Sinauer Associates. *LeVay S, Baldwin J, Baldwin J (Fifth ed., 2021). ''Discovering Human Sexuality''. New York: Oxford University Press. *LeVay S, (Second ed., 2016). '' Gay, Straight, and the Reason Why: The Science of Sexual Orientation''. New York: Oxford University Press. *LeVay S, (2013). ''The Donation of Constantine: A Novel''. Los Angeles: Lambourn Books.


References


External links


LeVay's home pageInterview With Dr. Simon LeVay
{{DEFAULTSORT:Levay, Simon 1943 births Alumni of the University of Cambridge American neuroscientists American sexologists Harvard Medical School alumni LGBT people from England LGBT scientists from the United Kingdom LGBT scientists from the United States American gay writers Living people People from Oxford Writers on LGBT topics University of California, San Diego faculty University of Göttingen alumni Gay academics Gay scientists Salk Institute for Biological Studies people