Sialography
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Sialography (also termed radiosialography) is the
radiographic Radiography is an imaging technique using X-rays, gamma rays, or similar ionizing radiation and non-ionizing radiation to view the internal form of an object. Applications of radiography include medical radiography ("diagnostic" and "therapeut ...
examination of the
salivary gland The salivary glands in mammals are exocrine glands that produce saliva through a system of ducts. Humans have three paired major salivary glands ( parotid, submandibular, and sublingual), as well as hundreds of minor salivary glands. Salivary ...
s. It usually involves the injection of a small amount of
contrast medium A contrast agent (or contrast medium) is a substance used to increase the contrast of structures or fluids within the body in medical imaging. Contrast agents absorb or alter external electromagnetism or ultrasound, which is different from radio ...
into the salivary duct of a single gland, followed by routine
X-ray An X-ray, or, much less commonly, X-radiation, is a penetrating form of high-energy electromagnetic radiation. Most X-rays have a wavelength ranging from 10  picometers to 10  nanometers, corresponding to frequencies in the range 30&nb ...
projections. The resulting image is called a sialogram. Sialography has largely been replaced by sialoendoscopy and cross-sectional imaging, such as CT,
MRI Magnetic resonance imaging (MRI) is a medical imaging technique used in radiology to form pictures of the anatomy and the physiological processes of the body. MRI scanners use strong magnetic fields, magnetic field gradients, and radio waves ...
and
ultrasonography Ultrasound is sound waves with frequencies higher than the upper audible limit of human hearing. Ultrasound is not different from "normal" (audible) sound in its physical properties, except that humans cannot hear it. This limit varies fr ...
.


Uses

This procedure is indicated when there is recurrent swelling and pain on the face but ultrasound has not revealed any problems. If Sjögren syndrome (also known as Sicca syndrome, an autoimmune disease that affects the lacrimal and salivary glands, causing reduced tears and saliva production) is suspected, this procedure is useful. Besides, when interventional proecudre is planned such as stone removal from salivary ducts or dilatation of the strictures in the salivary gland, this procedure is also indicated. However, for those who are pregnant, with allergy to
iodinated contrast Iodinated contrast is a form of intravenous radiocontrast agent containing iodine, which enhances the visibility of vascular structures and organs during radiographic procedures. Some pathologies, such as cancer, have particularly improved visib ...
, and ongoing infection or inflammation of the face, the procedure is contraindicated.


Procedure

Contrast agents are classified into two groups: fat-soluble contrast agents and water-soluble contrast agents. Water-soluble contrast agents can fill the finer elements of the ductal system. Fat-soluble contrast agents are viscous and can cause allergic reactions. These can also cause discomfort to the patients. Fat-soluble contrast agents do not fill finer elements of the duct. A baseline radiograph (scout film) of the required salivary gland would be taken, the duct is dilated using graded lacrimal probes, a
cannula A cannula (; Latin meaning 'little reed'; plural or ) is a tube that can be inserted into the body, often for the delivery or removal of fluid or for the gathering of samples. In simple terms, a cannula can surround the inner or outer surfaces ...
then is inserted in this salivary gland duct's opening in the mouth, then a radio-opaque fluid (contrast medium) is injected in the duct through a small tube. A series of radiographs would then be taken to determine the flow of the fluid, identify any obstructions and its location, the rate of fluid excretion from the gland. Usually the radiographs taken are lateral oblique views of the face as orthopantomograms are not useful for the purpose of locating the area due to superimpositions and the way they are taken to put the teeth in the main field.


Interpretation

This study is interpreted by evaluating the morphology of the salivary ducts for obstructions and chronic inflammation. Sialodochitis is a term describing dilation of the ducts caused by repeated inflammatory or infective processes. There is also irregular salivary duct stricture (narrowing) of the duct, which creates an appearance known as "sausage link" pattern on a sialogram. Suggestions of abscesses and autoimmune diseases such as Sjögren syndrome can also be elicited.
Sialadenitis Sialadenitis (sialoadenitis) is inflammation of salivary glands, usually the major ones, the most common being the parotid gland, followed by submandibular and sublingual glands. It should not be confused with sialadenosis (sialosis) which is a non ...
is inflammation of the salivary glands, which may cause acinar atrophy and create an appearance known as "pruning of the tree" on a sialogram, where there are less branches visible from the duct system. A space occupying lesion that occurs within or adjacent to a salivary gland can displace the normal anatomy of the gland. This may create an appearance known as "ball in hand" on an sialogram, where the ducts are curved around the mass of the lesion.


Adverse effects

Like any medical imaging utilizing ionizing radiation, there will be a degree of direct ionizing damage and indirect damage from
free radical A daughter category of ''Ageing'', this category deals only with the biological aspects of ageing. Ageing Ailments of unknown cause Biogerontology Biological processes Causes of death Cellular processes Gerontology Life extension Metabo ...
s created during the ionization of water molecules within cells. The risk of causing the development of a malignant tumor is incredibly small, and is weighed against the benefits of the investigation on a case-by-case basis. Possible complications include: * Pain on injection, * Post procedural infection, * Ductal rupture, * Extravasation of contrast media, * Allergic reaction to iodinated contrast media (which may present with
urticaria Hives, also known as urticaria, is a kind of skin rash with red, raised, itchy bumps. Hives may burn or sting. The patches of rash may appear on different body parts, with variable duration from minutes to days, and does not leave any long-last ...
,
dyspnoea Shortness of breath (SOB), also medically known as dyspnea (in AmE) or dyspnoea (in BrE), is an uncomfortable feeling of not being able to breathe well enough. The American Thoracic Society defines it as "a subjective experience of breathing dis ...
, and
hypotension Hypotension is low blood pressure. Blood pressure is the force of blood pushing against the walls of the arteries as the heart pumps out blood. Blood pressure is indicated by two numbers, the systolic blood pressure (the top number) and the dia ...
).


References

{{Medical imaging Projectional radiography Digestive system imaging