is an immunologist and a

Distinguished Professor Distinguished Professor is an academic title given to some top tenured professors in a university, school, or department. Some distinguished professors may have endowed chairs. In the United States Often specific to one institution, titles such ...

of Osaka University. He is best known for the discovery of

regulatory T cells The regulatory T cells (Tregs or Treg cells), formerly known as suppressor T cells, are a subpopulation of T cells that modulate the immune system, maintain tolerance to self-antigens, and prevent autoimmune disease. Treg cells are immunosu ...

and to describe their role in the

immune system The immune system is a network of biological processes that protects an organism from diseases. It detects and responds to a wide variety of pathogens, from viruses to parasitic worms, as well as cancer cells and objects such as wood splint ...

. This discovery is used in the treatment of

cancer Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. These contrast with benign tumors, which do not spread. Possible signs and symptoms include a lump, abnormal b ...

and autoimmune diseases.

Biography

Sakaguchi was born in Japan's

Shiga Prefecture is a prefecture of Japan located in the Kansai region of Honshu. Shiga Prefecture has a population of 1,412,916 (1 October 2015) and has a geographic area of . Shiga Prefecture borders Fukui Prefecture to the north, Gifu Prefecture to the north ...

and educated at Kyoto University. In 2015, the news agency

Thomson Reuters Thomson Reuters Corporation ( ) is a Canadian multinational media conglomerate. The company was founded in Toronto, Ontario, Canada, where it is headquartered at the Bay Adelaide Centre. Thomson Reuters was created by the Thomson Corpora ...

signals In signal processing, a signal is a function that conveys information about a phenomenon. Any quantity that can vary over space or time can be used as a signal to share messages between observers. The ''IEEE Transactions on Signal Processing'' ...

Shimon Sakaguchi among potential recipients of the

Nobel Prize in Physiology or Medicine The Nobel Prize in Physiology or Medicine is awarded yearly by the Nobel Assembly at the Karolinska Institute for outstanding discoveries in physiology or medicine. The Nobel Prize is not a single prize, but five separate prizes that, accord ...

Awards and recognition

* 2004:

William B. Coley Award The William B. Coley Award for Distinguished Research in Basic and Tumor Immunology is presented annually by the Cancer Research Institute, to scientists who have made outstanding achievements in the fields of basic and tumor immunology and whose w ...

* 2008:

Keio Medical Science Prize The Keio Medical Science Prize ( Japanese: 慶應医学賞) is a Japanese prize in medical sciences. Introduction The prize is awarded to scientists who made significant contributions to the field of medical sciences or life sciences. And these co ...

* 2009:

Medals of Honor (Japan) are medals awarded by the Government of Japan. They are awarded to individuals who have done meritorious deeds and also to those who have achieved excellence in their field of work. The Medals of Honor were established on December 7, 1881, and we ...

purple ribbon This is a partial list of awareness ribbons. The meaning behind an awareness ribbon Awareness ribbons are symbols meant to show support or raise consciousness for a cause. Different colours and patterns are associated with different issues. ...

* 2011:

Asahi Prize The , established in 1929, is an award presented by the Japanese newspaper ''Asahi Shimbun'' and Asahi Shimbun Foundation to honor individuals and groups that have made outstanding accomplishments in the fields of arts and academics and have greatl ...

* 2012: Foreign associate of the National Academy of Sciences * 2015:

Gairdner Foundation International Award The Canada Gairdner International Award is given annually by the Gairdner Foundation at a special dinner to five individuals for outstanding discoveries or contributions to medical science. Receipt of the Gairdner is traditionally considered a ...

. * 2017:

Crafoord Prize The Crafoord Prize is an annual science prize established in 1980 by Holger Crafoord, a Swedish industrialist, and his wife Anna-Greta Crafoord. The Prize is awarded in partnership between the Royal Swedish Academy of Sciences and the Crafoord Foun ...

* 2017: Person of Cultural Merit * 2017: Momofuku Ando Prize * 2019:

Order of Culture The is a Japanese order, established on February 11, 1937. The order has one class only, and may be awarded to men and women for contributions to Japan's art, literature, science, technology, or anything related to culture in general; recipient ...

* 2020:

Paul Ehrlich and Ludwig Darmstaedter Prize The Paul Ehrlich and Ludwig Darmstaedter Prize is an annual award bestowed by the since 1952 for investigations in medicine. It carries a prize money of 120,000 Euro. The prize awarding ceremony is traditionally held on March 14, the birthday of N ...

* 2020:

Robert Koch Prize The Robert Koch Medal and Award are two prizes awarded annually by the German for excellence in the biomedical sciences. These awards grew out of early attempts by German physician Robert Koch to generate funding to support his research into the ...

References

External links

*
Osaka University Immunology Frontier Research Center
{{DEFAULTSORT:Sakaguchi, Shimon 1951 births Living people Japanese immunologists Kyoto University alumni Foreign associates of the National Academy of Sciences Osaka University faculty Recipients of the Order of Culture