Human secretin receptor (gene name SCTR) is a
G protein-coupled receptor
G protein-coupled receptors (GPCRs), also known as seven-(pass)-transmembrane domain receptors, 7TM receptors, heptahelical receptors, serpentine receptors, and G protein-linked receptors (GPLR), form a large group of evolutionarily-related p ...
which binds
secretin
Secretin is a hormone that regulates water homeostasis throughout the body and influences the environment of the duodenum by regulating secretions in the stomach, pancreas, and liver. It is a peptide hormone produced in the S cells of the du ...
and is the leading member (''i.e.'', first cloned) of the class B GPCR subfamily.
Interactions
Secretin receptor has been shown to
interact
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with
pituitary adenylate cyclase activating peptide
Pituitary adenylate cyclase-activating polypeptide also known as PACAP is a protein that in humans is encoded by the ''ADCYAP1'' gene. pituitary adenylate cyclase-activating polypeptide is similar to vasoactive intestinal peptide. One of its effect ...
.
References
Further reading
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External links
IUPHAR GPCR Database - Secretin receptor*
G protein-coupled receptors
{{transmembranereceptor-stub