Saint Antoninus may refer to:
*Antoninus of Rome (died 186), martyr
*Antoninus of Pamiers (first, second, fourth, or fifth century), missionary and martyr, called the "Apostle of the Rouergue"
*Antoninus of Syria (died 303), martyr
*Antoninus of Piacenza (died 303), patron saint of Piacenza
*Antoninus Fontana (Antonino Fontana), archbishop of Milan (died 661)
*Antoninus of Florence (1389–1459)
*Antoninus of Sorrento (died 830 AD)
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