SB-215505 is a drug which acts as a potent and selective antagonist at the serotonin 5-HT_2B

receptor Receptor may refer to: * Sensory receptor, in physiology, any structure which, on receiving environmental stimuli, produces an informative nerve impulse *Receptor (biochemistry), in biochemistry, a protein molecule that receives and responds to a ...

, with good selectivity over the related 5-HT_2A and 5-HT_2C receptors. It is used in scientific research into the function of the 5-HT₂ family of receptors, especially to study the role of 5-HT_2B receptors in the heart, and to distinguish 5-HT_2B-mediated responses from those produced by 5-HT_2A or 5-HT_2C.

References

5-HT2B antagonists Chloroarenes Indolines Ureas Quinolines {{nervous-system-drug-stub