SB-200646 is a
5-HT2 receptor antagonist
A receptor antagonist is a type of receptor ligand or drug that blocks or dampens a biological response by binding to and blocking a receptor rather than activating it like an agonist. Antagonist drugs interfere in the natural operation of rece ...
with
anxiolytic properties in rats. It was the first 5-HT
2 antagonist discovered to have selectivity of
5-HT2C/
2B over
5-HT2A.
References
{{Serotonergics
5-HT2 antagonists
Anxiolytics
Indoles
3-Pyridyl compounds
Ureas