Pyrithyldione (Presidon, Persedon) is a

psychoactive drug A psychoactive drug, psychopharmaceutical, psychoactive agent or psychotropic drug is a chemical substance, that changes functions of the nervous system, and results in alterations in perception, mood, consciousness, cognition or behavior. ...

invented in 1949. An improved method of manufacture was patented by Roche in 1959. It was used as a hypnotic or sedative and presumed to be less toxic than barbiturates. Today, this substance is no longer used. Agranulocytosis was sometimes reported as

adverse effect An adverse effect is an undesired harmful effect resulting from a medication or other intervention, such as surgery. An adverse effect may be termed a " side effect", when judged to be secondary to a main or therapeutic effect. The term compl ...

. Pyrithyldione is also a CYP2D6 inducer but is not as potent as glutethimide s pyrithyldione (Benedorm) an enzyme inducer (author's transl)Pharmazie. 1982 Jan;37(1):69. In studies, it increased the O-Demethylation of codeine by 20%.

References

Hypnotics Lactams Ketones GABAA receptor positive allosteric modulators Abandoned drugs {{sedative-stub

See also

References