Propylpyrazoletriol (PPT) is a
synthetic Synthetic things are composed of multiple parts, often with the implication that they are artificial. In particular, 'synthetic' may refer to:
Science
* Synthetic chemical or compound, produced by the process of chemical synthesis
* Synthetic ...
,
nonsteroidal agonist of
ERα with 400-fold selectivity over
ERβ that is used widely in
scientific research to study the function of
ERα.
Though originally thought to be highly selective for ERα, PPT has subsequently been found to also act as an
agonist of the
GPER (GPR30).
See also
*
ERA-45
*
ERA-63
*
GTx-758
*
Methylpiperidinopyrazole
Methylpiperidinopyrazole (MPP) is a synthetic, nonsteroidal, and highly selective antagonist of ERα that is used in scientific research to study the function of this receptor. It has 200-fold selectivity for ERα over ERβ and 1000-fold sele ...
(MPP)
References
GPER agonists
Ketones
Phenols
Pyrazoles
Synthetic estrogens
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