Poly ICLC is an
immunostimulant
Immunostimulants, also known as immunostimulators, are substances (drugs and nutrients) that stimulate the immune system usually in a non-specific manner by inducing activation or increasing activity of any of its components. One notable example i ...
. It is
polyinosinic-polycytidylic acid (poly I:C) mixed with the stabilizers
carboxymethylcellulose and
polylysine.
It is under trial for use in cancer.
Poly I:C is a ligand for
toll like receptor-3, which usually triggers on the structurally similar
double-stranded RNA
Double-stranded RNA (dsRNA) is RNA with two complementary strands found in cells. It is similar to DNA but with the replacement of thymine by uracil and the adding of one oxygen atom. Despite the structural similarities, much less is known about ...
present in some viruses.
References
External links
* National Cancer Institute
poly ICLC
Immunostimulants
Combination drugs
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