Picrorhiza kurroa
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''Picrorhiza kurroa'' is one of the major income generating non-timber forest products found in the Nepalese
Himalayas The Himalayas, or Himalaya (; ; ), is a mountain range in Asia, separating the plains of the Indian subcontinent from the Tibetan Plateau. The range has some of the planet's highest peaks, including the very highest, Mount Everest. Over 10 ...
. It is one of the oldest medicinal plants traded from the
Karnali zone Karnali Zone ( ne, खसान अञ्चल) was one of the fourteen zones located in the Mid-Western Development Region of Nepal. The headquarters of Karnali Zone was Jumla. Karnali Zone was one of the poorest and most remote regions of ...
. Known as kutki or कुटकी in Nepali, it is a perennial herb and is used as a substitute for Indian
gentian ''Gentiana'' is a genus of flowering plants belonging to the gentian family (Gentianaceae), the tribe Gentianeae, and the monophyletic subtribe Gentianinae. With about 400 species it is considered a large genus. They are notable for their mostl ...
(''Gentiana kurroo'').


Habitat

It is found in the Himalayan region from Kashmir to
Sikkim Sikkim (; ) is a state in Northeastern India. It borders the Tibet Autonomous Region of China in the north and northeast, Bhutan in the east, Province No. 1 of Nepal in the west and West Bengal in the south. Sikkim is also close to the Silig ...
at an elevation of 2700–4500 m and in Nepal, found abundantly between 3500 and 4800 m. It is found far away from the community and takes from hours to days to walk to its growing habitat. It has been reported that ''Picrorhiza'' has been harvested to near extinction.


Description

Leaves: 5–15 cm long leaves, almost all at the base, often withered. Leaves are coarsely toothed, narrowed to a winged stalk.
Rhizomes of the plant are 15–25 cm long and woody.
Flowers: small, pale or purplish blue, borne in cylindric spikes, spikes borne on almost leafless erect stems. Flowers about 8 mm, 5-lobed to the middle, and with much longer stamens.
Fruits: 1.3 cm long. Chemistry: Chemical composition of ''Picrorhiza kurroa'' include Kutkin, a bitter glycoside which contains two C-9 iridoid glycosides, Picroside I and Kutakoside.


Conservation

In 1997, kutki was listed in appendix II of the Convention on International Trade in Endangered Species (CITES). This listing resulted ultimately from a request by the Indian government. Overharvesting of the wild species for use as medicine was cited as the main reason for the listing. The species not widely cultivated, though this has been discussed as a potential way to preserve wild stands, especially since the Dunagiri Foundation Trust has created, implemented, and successfully employed protocols to generate export-quality organic ethical 'Dunagiri Certified' Kutki since 2014. The International Union for Conservation of Nature Red List did not have a listing for this species as of 2014. ''Picrorhiza scrophulariiflora'' appears to be used heavily as a substitute for ''P. kurroa'' and is considered non-threatened by CITES.


Usage

The rhizome has a long history of use in Indian Ayurvedic medicine for the treatment of digestive problems. Other uses have been proposed (e.g. for asthma, liver damage, wound healing, vitiligo), but the medical evidence is not yet conclusive. It appears to be relatively safe based on its long history of traditional use. Kutki has hepato-protective properties and thus supports the liver and spleen. It is used in all forms of liver damage, cirrhosis, and inflammation of the liver. It protects the liver against damage from the hepatitis C virus.


References

{{Taxonbar, from=Q2562125 Flora of Nepal Plantaginaceae Herbs