Per-Ingvar Brånemark
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Per-Ingvar Brånemark (May 3, 1929 – December 20, 2014) was a Swedish physician and research professor, acknowledged as the "father of modern dental implantology". The ''Brånemark Osseointegration Center'' (BOC), named after its founder, was founded in 1989 in
Gothenburg Gothenburg (; abbreviated Gbg; sv, Göteborg ) is the second-largest city in Sweden, fifth-largest in the Nordic countries, and capital of the Västra Götaland County. It is situated by the Kattegat, on the west coast of Sweden, and has ...
, Sweden.


Biography

After studying at
Lund University , motto = Ad utrumque , mottoeng = Prepared for both , established = , type = Public research university , budget = SEK 9 billion Anatomy Anatomy () is the branch of biology concerned with the study of the structure of organisms and their parts. Anatomy is a branch of natural science that deals with the structural organization of living things. It is an old science, having i ...
at
Gothenburg University The University of Gothenburg ( sv, Göteborgs universitet) is a university in Sweden's second largest city, Gothenburg. Founded in 1891, the university is the third-oldest of the current Swedish universities and with 37,000 students and 6000 ...
in 1969. Brånemark has been awarded many prizes for his work, including the coveted Swedish Society of Medicine's Soederberg Prize in 1992—often referred to as the 'mini-
Nobel Nobel often refers to: *Nobel Prize, awarded annually since 1901, from the bequest of Swedish inventor Alfred Nobel Nobel may also refer to: Companies *AkzoNobel, the result of the merger between Akzo and Nobel Industries in 1994 *Branobel, or ...
'—and the Swedish Engineering Academy's equally prestigious medal for technical innovation. Brånemark has also been honored with the Harvard School of Dental Medicine Medal for his work on dental implants in the
United States The United States of America (U.S.A. or USA), commonly known as the United States (U.S. or US) or America, is a country Continental United States, primarily located in North America. It consists of 50 U.S. state, states, a Washington, D.C., ...
and holds more than 30 honorary positions throughout
Europe Europe is a large peninsula conventionally considered a continent in its own right because of its great physical size and the weight of its history and traditions. Europe is also considered a Continent#Subcontinents, subcontinent of Eurasia ...
and
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, including the Honorary Fellowship of the
Royal Society of Medicine The Royal Society of Medicine (RSM) is a medical society in the United Kingdom, headquartered in London. History The Society was established in 1805 as Medical and Chirurgical Society of London, meeting in two rooms in barristers’ chambers ...
in the UK. In 2003, he received an
honorary doctorate An honorary degree is an academic degree for which a university (or other degree-awarding institution) has waived all of the usual requirements. It is also known by the Latin phrases ''honoris causa'' ("for the sake of the honour") or ''ad hono ...
from the
European University of Madrid European University of Madrid (''Universidad Europea de Madrid'' in Spanish language, UEM) is a private university in Madrid, Spain. History Founded in 1995, the school was purchased in 1999 by Sylvan Learning Systems, Inc. In 2004, Sylvan Le ...
. He was the winner of the
European Inventor Award The European Inventor Award(formerly European Inventor of the Year Award, renamed in 2010), are presented annually by the European Patent Office, sometimes supported by the respective Presidency of the Council of the European Union and by the Eur ...
2011 in the category Lifetime achievement. In 2014, he died at the age of 85.


Dental implantology

In 1978, the first Dental Implant Consensus Conference was held, sponsored jointly by the
National Institutes of Health The National Institutes of Health, commonly referred to as NIH (with each letter pronounced individually), is the primary agency of the United States government responsible for biomedical and public health research. It was founded in the lat ...
and
Harvard University Harvard University is a private Ivy League research university in Cambridge, Massachusetts. Founded in 1636 as Harvard College and named for its first benefactor, the Puritan clergyman John Harvard, it is the oldest institution of highe ...
. It was a landmark event, at which
retrospective A retrospective (from Latin ''retrospectare'', "look back"), generally, is a look back at events that took place, or works that were produced, in the past. As a noun, ''retrospective'' has specific meanings in medicine, software development, popu ...
data on dental implants were collected and analyzed and criteria and standards for implant dentistry were established. In 1982 in
Toronto Toronto ( ; or ) is the capital city of the Canadian province of Ontario. With a recorded population of 2,794,356 in 2021, it is the most populous city in Canada and the fourth most populous city in North America. The city is the anch ...
, Brånemark presented work that had begun 15 years earlier in Gothenburg. Brånemark's investigations into the phenomenon of osseointegration, or the biological fusion of
bone A bone is a rigid organ that constitutes part of the skeleton in most vertebrate animals. Bones protect the various other organs of the body, produce red and white blood cells, store minerals, provide structure and support for the body, ...
to a foreign material, reinvigorated the field of implantology. The Toronto conference brought widespread recognition to the Brånemark implant methods and materials and is one of the most significant scientific breakthroughs in
dentistry Dentistry, also known as dental medicine and oral medicine, is the branch of medicine focused on the teeth, gums, and mouth. It consists of the study, diagnosis, prevention, management, and treatment of diseases, disorders, and conditions of ...
since the late 1970s. The Brånemark System of dental implants was bought out and is currently available from Nobel Biocare.


Work on osseointegration

Brånemark's work in the field of osseointegration reinvigorated the realm of implant dentistry and brought it from being a shunned field into one that became recognized and incorporated into dental school curricula and training programs.Shulman, LB; Driskell, TD: Dental Implants: A Historical Perspective. In Block, M; Kent, J; Guerra, L, editors: ''Implants in Dentistry''. Philadelphia: W.B. Saunders, 1997. page 6. Early modern dental implant technology consisted of blade and transosteal implants. Blade implants, introduced in 1967, consisted of a metal blade that was placed within a bony incision that subsequently healed over the horizontally situated piece of metal but allowed a vertical segment to perforate the healed surface. Transosteal implants, the application of which was strictly limited to the
mandible In anatomy, the mandible, lower jaw or jawbone is the largest, strongest and lowest bone in the human facial skeleton. It forms the lower jaw and holds the lower teeth in place. The mandible sits beneath the maxilla. It is the only movable bone ...
, consisted of a number of screws which were inserted into the inferior aspect of the mandible, some of which extended through and through into the oral cavity.Shulman, LB; Driskell, TD: Dental Implants: A Historical Perspective. In Block, M; Kent, J; Guerra, L, editors: ''Implants in Dentistry''. Philadelphia: W.B. Saunders, 1997. page 6 It was previously thought that both of these implant types relied on mechanical retention, as it was heretofore unknown that metal could be fused into the bone. With the advent of our current understanding of osseointegration however, rootform endosteal implants became the new standard in implant technology. The phenomenon of osseointegration was first described by Bothe et al. in 1940 and later by Leventhal et al. in 1951. Brånemark's studies, and his subsequent coining of the phrase osseointegration, occurred a year after Leventhal during vital
microscopy Microscopy is the technical field of using microscopes to view objects and areas of objects that cannot be seen with the naked eye (objects that are not within the resolution range of the normal eye). There are three well-known branches of micr ...
studies in
rabbit Rabbits, also known as bunnies or bunny rabbits, are small mammals in the family Leporidae (which also contains the hares) of the order Lagomorpha (which also contains the pikas). ''Oryctolagus cuniculus'' includes the European rabbit sp ...
s using titanium optic chambers. He and his team found that
titanium Titanium is a chemical element with the symbol Ti and atomic number 22. Found in nature only as an oxide, it can be reduced to produce a lustrous transition metal with a silver color, low density, and high strength, resistant to corrosion i ...
ocular Eyes are organs of the visual system. They provide living organisms with vision, the ability to receive and process visual detail, as well as enabling several photo response functions that are independent of vision. Eyes detect light and conv ...
s placed into the lower leg bones of rabbits could not be removed from the bones after a period of healing (see photo at right). He then developed and tested a type of dental implant utilizing pure titanium screws, which he termed ''fixtures''. Although the field of implantology was eschewed by dental academia until that time, the "extensive and weighty documentation of implant efficacy and safety" and "early replication by reliable, independent researchers" resulted in the widespread embrace of implantology by the dental community. Brånemark's son, Rickard, has taken this success and is developing orthopedic
prostheses In medicine, a prosthesis (plural: prostheses; from grc, πρόσθεσις, prósthesis, addition, application, attachment), or a prosthetic implant, is an artificial device that replaces a missing body part, which may be lost through trau ...
in the form of artificial arms and legs anchored to the
human skeleton The human skeleton is the internal framework of the human body. It is composed of around 270 bones at birth – this total decreases to around 206 bones by adulthood after some bones get fused together. The bone mass in the skeleton makes up a ...
. Gösta Larsson (1931–2006) was the first recipient ever of a modern dental implant, which occurred in 1965. Prof. Per-Ingvar Brånemark, by then Professor of Anatomy at
Gothenburg University The University of Gothenburg ( sv, Göteborgs universitet) is a university in Sweden's second largest city, Gothenburg. Founded in 1891, the university is the third-oldest of the current Swedish universities and with 37,000 students and 6000 ...
in Sweden, placed the first
titanium Titanium is a chemical element with the symbol Ti and atomic number 22. Found in nature only as an oxide, it can be reduced to produce a lustrous transition metal with a silver color, low density, and high strength, resistant to corrosion i ...
dental implant into a human volunteer. Larsson, a Swede who was edentulous at the time and had been born with severe chin and jaw deformities, agreed to the test because he wanted to have teeth again. He died in 2006, having used his implants for over 40 years.The History Of Dental Implantation
, implantru.com, accessed 2010-06-13


See also

*
Osseoincorporation Osseoincorporation refers to the healing potential of bone onto an implant surface and into an implant structure. Three-dimensional, porous implantable materials used in the orthopedic and dental implant industries offer the potential for ingrowt ...
* Dental Implants * Osseointegration


References


External links


Nobel Biocare Convention 2007Bacterial Persistence in Dentoalveolar Bone Following Extraction: A Microbiological Study and Implications for Dental Implant Treatment - Clinical Implant Dentistry and Related Research
{{DEFAULTSORT:Branemark, Per-Ingvar 1929 births 2014 deaths Dental materials Academic staff of the University of Gothenburg European Inventor Award winners