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Pelanserin (TR2515) is an antagonist of the 5-HT2 and α1-adrenergic receptors.
The reaction between isatoic anhydride (1) and 1-(3-Aminopropyl)-4-phenylpiperazine 0529-19-5(2) with phosgene completed the synthesis of pelanserin (3).
Synthesis
The reaction between isatoic anhydride (1) and 1-(3-Aminopropyl)-4-phenylpiperazine 0529-19-5(2) with phosgene completed the synthesis of pelanserin (3).
See also
*Ketanserin
Ketanserin ( INN, USAN, BAN) (brand name Sufrexal; former developmental code name R41468) is a drug used clinically as an antihypertensive agent and in scientific research to study the serotonin system; specifically, the 5-HT2 receptor family. I ...
References
5-HT2 antagonists Alpha-1 blockers {{pharma-stub