PNU-120596 is a drug that acts as a potent and selective

positive allosteric modulator In pharmacology and biochemistry, allosteric modulators are a group of substances that bind to a receptor to change that receptor's response to stimulus. Some of them, like benzodiazepines, are drugs. The site that an allosteric modulator binds to ...

for the α7 subtype of neural

nicotinic acetylcholine receptor Nicotinic acetylcholine receptors, or nAChRs, are receptor polypeptides that respond to the neurotransmitter acetylcholine. Nicotinic receptors also respond to drugs such as the agonist nicotine. They are found in the central and peripheral ner ...

s. It is used in scientific research into cholinergic regulation of dopamine and glutamate release in the brain.

References

Nicotinic agonists Stimulants Phenol ethers Chloroarenes Ureas Isoxazoles {{nervous-system-drug-stub