PF-184563 is a potent, selective non-peptidic antagonist of the V1a receptor. The compound was discovered by

Pfizer Pfizer Inc. ( ) is an American multinational pharmaceutical and biotechnology corporation headquartered on 42nd Street in Manhattan, New York City. The company was established in 1849 in New York by two German entrepreneurs, Charles Pfizer ...

in its

Sandwich, Kent Sandwich is a town and civil parish in the Dover District of Kent, south-east England. It lies on the River Stour and has a population of 4,985. Sandwich was one of the Cinque Ports and still has many original medieval buildings, including s ...

research center, as a potential treatment for

dysmenorrhoea Dysmenorrhea, also known as period pain, painful periods or menstrual cramps, is pain during menstruation. Its usual onset occurs around the time that menstruation begins. Symptoms typically last less than three days. The pain is usually in the ...

, an indication for which V1a antagonists have shown efficacy.

References

Drugs developed by Pfizer Vasopressin receptor antagonists {{systemic-hormonal-drug-stub