Osaterone (developmental code name TZP-5258), also known as 17α-hydroxy-6-chloro-2-oxa-6-dehydroprogesterone, as well as 2-oxachloromadinone, is a
steroidal
antiandrogen
Antiandrogens, also known as androgen antagonists or testosterone blockers, are a class of drugs that prevent androgens like testosterone and dihydrotestosterone (DHT) from mediating their biological effects in the body. They act by blocking the ...
and
progestin that was never marketed.
The C17α
acetate ester
In chemistry, an ester is a compound derived from an oxoacid (organic or inorganic) in which at least one hydroxyl group () is replaced by an alkoxy group (), as in the substitution reaction of a carboxylic acid and an alcohol. Glycerides a ...
of osaterone,
osaterone acetate
Osaterone (developmental code name TZP-5258), also known as 17α-hydroxy-6-chloro-2-oxa-6-dehydroprogesterone, as well as 2-oxachloromadinone, is a steroidal antiandrogen and progestin that was never marketed. The C17α acetate ester
In chem ...
, in contrast, has been marketed.
See also
*
Chlormadinone
Chlormadinone is a progestin which was never marketed. An acylated derivative, chlormadinone acetate
Chlormadinone acetate (CMA), sold under the brand names Belara, Gynorelle, Lutéran, and Prostal among others, is a progestin and antiandroge ...
*
Delmadinone
Delmadinone ( INN) is a steroidal progestin which was never marketed. An acylated derivative, delmadinone acetate, is used in veterinary medicine
Veterinary medicine is the branch of medicine that deals with the prevention, management, diagn ...
*
Oxendolone
Oxendolone, sold under the brand names Prostetin and Roxenone, is an antiandrogen and progestin medication which is used in Japan in the treatment of enlarged prostate. However, this use is controversial due to concerns about its clinical effic ...
References
Organochlorides
Pregnanes
Progestogens
Steroidal antiandrogens
Delta-lactones
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