Natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B), also known as NPR2, is an
atrial natriuretic peptide receptor
An atrial natriuretic peptide receptor is a receptor for atrial natriuretic peptide.
Mechanism
NPRA and NPRB are linked to guanylyl cyclases, while NPRC is G-protein-linked and is a "clearance receptor" that acts to internalise and destroy th ...
. In humans it is encoded by the NPR2
gene
In biology, the word gene (from , ; "... Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' or ''birth'' or ''gender'') can have several different meanings. The Mendelian gene is a b ...
.
A
mutation
In biology, a mutation is an alteration in the nucleic acid sequence of the genome of an organism, virus, or extrachromosomal DNA. Viral genomes contain either DNA or RNA. Mutations result from errors during DNA replication, DNA or viral repl ...
of the NPR2 gene can result in
disproportionate dwarfism with short limbs.
See also
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Atrial natriuretic peptide receptor
An atrial natriuretic peptide receptor is a receptor for atrial natriuretic peptide.
Mechanism
NPRA and NPRB are linked to guanylyl cyclases, while NPRC is G-protein-linked and is a "clearance receptor" that acts to internalise and destroy th ...
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Dwarfism
References
Further reading
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External links
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EC 4.6.1
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