NESS-040C5 is a potent
cannabinoid agonist which was developed for the treatment of
glaucoma
Glaucoma is a group of eye diseases that result in damage to the optic nerve (or retina) and cause vision loss. The most common type is open-angle (wide angle, chronic simple) glaucoma, in which the drainage angle for aqueous humor, fluid withi ...
. It has reasonable selectivity for the
CB2 receptor subtype, having a CB
2 affinity of 0.4nM, and 25x selectivity over the related
CB1 receptor.
See also
*
AB-FUBINACA
*
NESS-0327
*
SR-144,528
References
{{cannabinoid-stub
Cannabinoids