NAN-190 is a
drug and research chemical widely used in scientific studies. It was previously believed to act as a selective
5-HT1A receptor
Receptor may refer to:
* Sensory receptor, in physiology, any structure which, on receiving environmental stimuli, produces an informative nerve impulse
*Receptor (biochemistry), in biochemistry, a protein molecule that receives and responds to a ...
antagonist, but a subsequent discovery showed that it also potently blocks the
α2-adrenergic receptor.
The new finding has raised significant concerns about studies using NAN-190 as a specific
serotonin receptor antagonist.
References
5-HT1A antagonists
Abandoned drugs
Alpha-2 blockers
Phenol ethers
Phenylpiperazines
Phthalimides
{{Antihypertensive-stub