In enzymology, a myosin-heavy-chain kinase () is an

enzyme Enzymes () are proteins that act as biological catalysts by accelerating chemical reactions. The molecules upon which enzymes may act are called substrates, and the enzyme converts the substrates into different molecules known as products ...

that catalyzes the

chemical reaction A chemical reaction is a process that leads to the IUPAC nomenclature for organic transformations, chemical transformation of one set of chemical substances to another. Classically, chemical reactions encompass changes that only involve the pos ...

:ATP + yosin heavy-chain

\rightleftharpoons

ADP + yosin heavy-chainphosphate Thus, the two substrates of this enzyme are ATP and myosin heavy-chain, whereas its two

products Product may refer to: Business * Product (business), an item that serves as a solution to a specific consumer problem. * Product (project management), a deliverable or set of deliverables that contribute to a business solution Mathematics * Produ ...

are ADP and myosin heavy-chain phosphate. This enzyme belongs to the family of

transferase A transferase is any one of a class of enzymes that catalyse the transfer of specific functional groups (e.g. a methyl or glycosyl group) from one molecule (called the donor) to another (called the acceptor). They are involved in hundreds of ...

s, specifically those transferring a phosphate group to the sidechain

oxygen Oxygen is the chemical element with the symbol O and atomic number 8. It is a member of the chalcogen group in the periodic table, a highly reactive nonmetal, and an oxidizing agent that readily forms oxides with most elements as ...

atom of serine or threonine residues in

protein Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, res ...

s ( protein-serine/threonine kinases). The

systematic name A systematic name is a name given in a systematic way to one unique group, organism, object or chemical substance, out of a specific population or collection. Systematic names are usually part of a nomenclature. A semisystematic name or semitrivial ...

of this enzyme class is ATP: yosin heavy-chainO-phosphotransferase. Other names in common use include *ATP:myosin-heavy-chain O-phosphotransferase *calmodulin-dependent myosin heavy chain kinase *MHCK *MIHC kinase *myosin heavy chain kinase *myosin I heavy-chain kinase *myosin II heavy-chain kinase * yosin-heavy-chainkinase *myosin heavy chain kinase A *STK6.

References

* * * * * * * * * EC 2.7.11 Enzymes of unknown structure {{2.7-enzyme-stub