Miguel Nicolelis
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Miguel Ângelo Laporta Nicolelis,
M.D. Doctor of Medicine (abbreviated M.D., from the Latin ''Medicinae Doctor'') is a medical degree, the meaning of which varies between different jurisdictions. In the United States, and some other countries, the M.D. denotes a professional degree. ...
,
Ph.D. A Doctor of Philosophy (PhD, Ph.D., or DPhil; Latin: or ') is the most common degree at the highest academic level awarded following a course of study. PhDs are awarded for programs across the whole breadth of academic fields. Because it is ...
(, born March 7, 1961), is a Brazilian
scientist A scientist is a person who conducts Scientific method, scientific research to advance knowledge in an Branches of science, area of the natural sciences. In classical antiquity, there was no real ancient analog of a modern scientist. Instead, ...
,
physician A physician (American English), medical practitioner (Commonwealth English), medical doctor, or simply doctor, is a health professional who practices medicine, which is concerned with promoting, maintaining or restoring health through th ...
and Duke School of Medicine Professor in Neuroscience at
Duke University Duke University is a private research university in Durham, North Carolina. Founded by Methodists and Quakers in the present-day city of Trinity in 1838, the school moved to Durham in 1892. In 1924, tobacco and electric power industrialist James ...
, best known for his pioneering work surrounding brain-computer interface (also known as "brain-machine interface") technology.


Biography

Nicolelis holds a medical degree from the University of São Paulo (1984), a doctorate in Sciences (General Physiology) from the
University of São Paulo The University of São Paulo ( pt, Universidade de São Paulo, USP) is a public university in the Brazilian state of São Paulo. It is the largest Brazilian public university and the country's most prestigious educational institution, the bes ...
(1989) and a PhD in Physiology and Biophysics from Hahnemann University (now
Drexel University College of Medicine Drexel University College of Medicine is the medical school of Drexel University, a private research university in Philadelphia, Pennsylvania. The medical school represents the consolidation of two medical schools: the first U.S. medical school f ...
). He is a full professor in the Department of Neurobiology and Co-Director of the Neuroengineering Center at Duke University (USA). Founder of the Alberto Santos Dumont Association for Research Support (AASDAP) and the Santos Dumont Institute (ISD), he proposed the use of science as an agent of social and economic transformation. Nicolelis is a Researcher at the International Institute of Neurosciences Edmond and Lily Safra (IIN-ELS) and Coordinator of the Andar de Novo Project, developed at AASDAP in São Paulo. He and his colleagues at
Duke University Duke University is a private research university in Durham, North Carolina. Founded by Methodists and Quakers in the present-day city of Trinity in 1838, the school moved to Durham in 1892. In 1924, tobacco and electric power industrialist James ...
implanted
electrode An electrode is an electrical conductor used to make contact with a nonmetallic part of a circuit (e.g. a semiconductor, an electrolyte, a vacuum or air). Electrodes are essential parts of batteries that can consist of a variety of materials d ...
arrays into a
monkey Monkey is a common name that may refer to most mammals of the infraorder Simiiformes, also known as the simians. Traditionally, all animals in the group now known as simians are counted as monkeys except the apes, which constitutes an incomple ...
's
brain A brain is an organ that serves as the center of the nervous system in all vertebrate and most invertebrate animals. It is located in the head, usually close to the sensory organs for senses such as vision. It is the most complex organ in a v ...
that were able to detect the monkey's motor intent and thus able to control reaching and grasping
movements Movement may refer to: Common uses * Movement (clockwork), the internal mechanism of a timepiece * Motion, commonly referred to as movement Arts, entertainment, and media Literature * "Movement" (short story), a short story by Nancy Fu ...
performed by a
robot A robot is a machine—especially one programmable by a computer—capable of carrying out a complex series of actions automatically. A robot can be guided by an external control device, or the control may be embedded within. Robots may be c ...
ic arm. This was possible by decoding signals of hundreds of
neuron A neuron, neurone, or nerve cell is an electrically excitable cell that communicates with other cells via specialized connections called synapses. The neuron is the main component of nervous tissue in all animals except sponges and placozoa. N ...
s recorded in volitional areas of the
cerebral cortex The cerebral cortex, also known as the cerebral mantle, is the outer layer of neural tissue of the cerebrum of the brain in humans and other mammals. The cerebral cortex mostly consists of the six-layered neocortex, with just 10% consistin ...
while the monkey played with a hand-held joystick to move a shape in a video game. These signals were sent to the robot arm, which then mimicked the monkey's movements and thus controlled the game. After a while the monkey realised that thinking about moving the shape was enough and it no longer needed to move the joystick. So it let go of the joystick and controlled the game purely through thought. A system in which brain signals directly control an artificial actuator is commonly referred to as brain-computer interface ("BCI"). On January 15, 2008, Dr. Nicolelis lab saw a monkey implanted with a new BCI successfully control a robot walking on a treadmill in Kyoto, Japan. The monkey could see the robot, named CB, on a screen in front of him, and was rewarded for walking in sync with the robot (which was under the control of the monkey). After an hour the monkey's treadmill was turned off, but he was able to continue to direct the robot to walk normally for another few minutes, indicating that a part of the brain not sufficient to induce a motor response in the monkey had become dedicated to controlling the robot, as if it were an extension of itself. Nicolelis is a co-founder and scientific director of the Edmond and Lily Safra International Institute for Neuroscience of Natal, a brain research facility in Brazil. On August 3, 2010, Nicolelis was awarded an NIH Director's Pioneer Award to continue his research on brain-machine interface technology. On January 5, 2011, Dr. Nicolelis was appointed by Pope Benedict XVI as an ordinary member of the Pontifical Academy of Sciences. Nicolelis is a fan of
Sociedade Esportiva Palmeiras Sociedade Esportiva Palmeiras (), commonly known as Palmeiras, is a Brazilian professional football club based in the city of São Paulo, in the district of Perdizes. Palmeiras is one of the most popular clubs in South America, with around ...
, a Brazilian football club; a football ball with Palmeiras crest can be seen at his website. He is currently working on a project that allowed paraplegic Juliano Pinto, a 29-year-old with complete paralysis of the lower trunk to deliver the kickoff at the opening game of the
2014 FIFA World Cup The 2014 FIFA World Cup was the 20th FIFA World Cup, the quadrennial world championship for men's national football teams organised by FIFA. It took place in Brazil from 12 June to 13 July 2014, after the country was awarded the hosting ri ...
, in Brazil.


Brain to brain

In 2013, a report of research by Nicolelis and others was published which showed brain to brain communication between two rats using
brain–computer interface A brain–computer interface (BCI), sometimes called a brain–machine interface (BMI) or smartbrain, is a direct communication pathway between the brain's electrical activity and an external device, most commonly a computer or robotic limb. B ...
s. This result may demonstrate the feasibility of a
biological computer Biological computers use biologically derived molecules — such as DNA and/or proteins — to perform digital or real computations. The development of biocomputers has been made possible by the expanding new science of nanobiotechnology. The t ...
consisting of a
network Network, networking and networked may refer to: Science and technology * Network theory, the study of graphs as a representation of relations between discrete objects * Network science, an academic field that studies complex networks Mathematics ...
of animal, or human, brains. Currently, researchers are divided on their views of this research. Critics state that there are flaws in the scientific methods used and that there is lack of controls. They claim that some of the scientific claims are rendered "far-fetched at best." One researcher stated the work was similar to a "poor Hollywood science fiction script." Proponents have praised this research for drawing attention to Brain to Brain Interfaces as a way of studying neural systems: “The study helps to promote the role of BMIs not only in prosthetic applications, but also as scientific tools. It's a contribution to that.” Ron Frostig, a neuroscientist at the University of California, Irvine, has described this brain to brain work as "an amazing paper” and a “beautiful proof of principle” that information can be transferred from one brain to another in real time.


The True Creator of Everything

In August 10, 2020, the neuroscientist Nicolelis published his book entitled “The True Creator of Everything: How the Human Brain Shaped the Universe as We Know It.” It’s the third book of a trilogy that starts with the book “Muito Além do Nosso eu (portuguese version)” in 2011, and continues with “Made In Macaíba” published in 2016. In this book, Nicolelis explores the thesis that the human brain would be the center of the universe and tries to explain the history, the culture and the human civilization based on recently discovered principles regarding human brain function: “The True Creator of Everything is a story about the creations of the human brain and the center position it should occupy in the cosmology of the universe.” According to the author, the human mind works in a relative way, meaning that every movement is relative and the mind creates its own model of reality, which is constantly renewed with the information it obtains from the world. Such theory is called by Nicolelis as the “Theory of The Relativistic Brain.” Based on the TRB, the author launched himself in an ambitious project for the book, which consisted in argumenting the center position the human brain has in different areas of scientific knowledge, not limited to neuroscience. During this project, Nicolelis read the book “The Story Of Art” by Ernst H. Gombrich, which inspired the author to proceed with such project.


Further reading

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Selected Publications on Brain-Machine Interfaces

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References


External links


Nicolelis Lab

CV and awards
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International Institute for Neuroscience of Natal (IINN)
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"Minds and Machines – A conversation with Miguel Nicolelis"
''Ideas Roadshow'', 2013 {{DEFAULTSORT:Nicolelis, Miguel 1961 births Living people Brazilian neuroscientists Brazilian people of Italian descent Brain–computer interfacing University of São Paulo alumni Duke University faculty Brazilian people of Greek descent Members of the French Academy of Sciences Brazilian expatriate academics in the United States American people of Brazilian descent Drexel University alumni