Zymotic disease was a 19th-century medical term for acute

infectious disease An infection is the invasion of tissues by pathogens, their multiplication, and the reaction of host tissues to the infectious agent and the toxins they produce. An infectious disease, also known as a transmissible disease or communicable di ...

s, especially "chief fevers and contagious diseases (e.g.

typhus Typhus, also known as typhus fever, is a group of infectious diseases that include epidemic typhus, scrub typhus, and murine typhus. Common symptoms include fever, headache, and a rash. Typically these begin one to two weeks after exposure. ...

and

typhoid fever Typhoid fever, also known as typhoid, is a disease caused by '' Salmonella'' serotype Typhi bacteria. Symptoms vary from mild to severe, and usually begin six to 30 days after exposure. Often there is a gradual onset of a high fever over several ...

smallpox Smallpox was an infectious disease caused by variola virus (often called smallpox virus) which belongs to the genus Orthopoxvirus. The last naturally occurring case was diagnosed in October 1977, and the World Health Organization (WHO) c ...

, scarlet fever, measles,

erysipelas Erysipelas () is a relatively common bacterial infection of the superficial layer of the skin ( upper dermis), extending to the superficial lymphatic vessels within the skin, characterized by a raised, well-defined, tender, bright red rash, t ...

, cholera,

whooping-cough Whooping cough, also known as pertussis or the 100-day cough, is a highly contagious bacterial disease. Initial symptoms are usually similar to those of the common cold with a runny nose, fever, and mild cough, but these are followed by two or ...

diphtheria Diphtheria is an infection caused by the bacterium '' Corynebacterium diphtheriae''. Most infections are asymptomatic or have a mild clinical course, but in some outbreaks more than 10% of those diagnosed with the disease may die. Signs and s ...

, etc.)". Zyme or microzyme was the name of the organism presumed to be the cause of the disease.

As originally employed by
William Farr William Farr CB (30 November 1807 – 14 April 1883) was a British epidemiologist, regarded as one of the founders of medical statistics. Early life William Farr was born in Kenley, Shropshire, to poor parents. He was effectively adopted b ...
, of the British Registrar-General's department, the term included the diseases which were "epidemic, endemic and contagious," and were regarded as owing their origin to the presence of a morbific principle in the system, acting in a manner analogous to, although not identical with, the process of fermentation.

In the late 19th century,

Antoine Béchamp Pierre Jacques Antoine Béchamp (16 October 1816 – 15 April 1908) was a French scientist now best known for breakthroughs in applied organic chemistry and for a bitter rivalry with Louis Pasteur. Béchamp developed the Béchamp reduction ...

proposed that tiny organisms he termed ''microzymas'', and not cells, are the fundamental building block of life. Béchamp claimed these microzymas are present in all things—animal, vegetable, and mineral—whether living or dead. Microzymas coalesce to form blood clots and bacteria. Depending upon the condition of the host, microzymas assume various forms. In a diseased body, the microzymas become pathological bacteria and viruses. In a healthy body, microzymas form healthy cells. When a plant or animal dies, the microzymas live on. His ideas did not gain acceptance. The word ''zymotic'' comes from the

Greek Greek may refer to: Greece Anything of, from, or related to Greece, a country in Southern Europe: *Greeks, an ethnic group. *Greek language, a branch of the Indo-European language family. **Proto-Greek language, the assumed last common ancestor ...

word ζυμοῦν ''zumoûn'' which means "to ferment". It was in British official use from 1839. This term was used extensively in the English Bills of Mortality as a cause of death from 1842. In 1877, Thomas Watson wrote in a ''

Scientific American ''Scientific American'', informally abbreviated ''SciAm'' or sometimes ''SA'', is an American popular science magazine. Many famous scientists, including Albert Einstein and Nikola Tesla, have contributed articles to it. In print since 1845, it ...

'' article "Zymotic Disease" describing contagion as the origin of infectious diseases. Robert Newstead (1859–1947) used this term in a 1908 publication in the ''Annals of Tropical Medicine and Parasitology'', to describe the contribution of house flies (''

Musca domestica The housefly (''Musca domestica'') is a fly of the suborder Cyclorrhapha. It is believed to have evolved in the Cenozoic Era, possibly in the Middle East, and has spread all over the world as a commensal of humans. It is the most common f ...

'') towards the spread of infectious diseases. However, by the early 1900s,

bacteriology Bacteriology is the branch and specialty of biology that studies the morphology, ecology, genetics and biochemistry of bacteria as well as many other aspects related to them. This subdivision of microbiology involves the identification, classificat ...

"displaced the old

fermentation theory In biochemistry, fermentation theory refers to the historical study of models of natural fermentation processes, especially alcoholic and lactic acid fermentation. Notable contributors to the theory include Justus Von Liebig and Louis Pasteur, th ...

", and so the term became obsolete. In her ''Diagram of the causes of mortality in the army in the East'',

Florence Nightingale Florence Nightingale (; 12 May 1820 – 13 August 1910) was an English social reformer, statistician and the founder of modern nursing. Nightingale came to prominence while serving as a manager and trainer of nurses during the Crimean War, i ...

depicts

The blue wedges measured from the centre of the circle represent area for area the deaths from Preventible or Mitigable Zymotic diseases; the red wedges measured from the centre the deaths from wounds, & the black wedges measured from the centre the deaths from all other causes.

References

{{DEFAULTSORT:Zymotic Disease Medical terminology Obsolete medical theories