Matthias H. Tschöp (born April 7, 1967) is a German physician and scientist. He is the

chief executive officer A chief executive officer (CEO), also known as a central executive officer (CEO), chief administrator officer (CAO) or just chief executive (CE), is one of a number of corporate executives charged with the management of an organization especial ...

and scientific director of

Helmholtz Zentrum München Helmholtz Zentrum München Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH), also known as Helmholtz Munich, is a member of the Helmholtz Association of German Research Centres. It was founded in 1960 and is a joint venture by the Fede ...

, German Research Center for Environmental Health. He is also

Alexander von Humboldt Professor The Alexander von Humboldt Professorship is an academic prize named after Alexander von Humboldt and awarded by the Alexander von Humboldt Foundation since 2008. The prize is intended to attract internationally leading scientists from abroad to Ger ...

and chair of metabolic diseases at

Technical University of Munich The Technical University of Munich (TUM or TU Munich; german: Technische Universität München) is a public research university in Munich, Germany. It specializes in engineering, technology, medicine, and applied and natural sciences. Establis ...

and serves as an adjunct professor at

Yale University Yale University is a Private university, private research university in New Haven, Connecticut. Established in 1701 as the Collegiate School, it is the List of Colonial Colleges, third-oldest institution of higher education in the United Sta ...

Career and research

Tschöp obtained an M.D. from the Ludwig Maximilian University of Munich (1993), where he worked as a clinician (1994–1998) in neuroendocrinology before accepting a research fellowship at the Eli Lilly Discovery Research Laboratories (1999–2002) and leading a research team at th
German Institute of Human Nutrition
(Potsdam/Nuthetal 2002–2003). He served as a Professor of Endocrinology and Diabetes at the Metabolic Diseases Institute of the

University of Cincinnati The University of Cincinnati (UC or Cincinnati) is a public research university in Cincinnati, Ohio. Founded in 1819 as Cincinnati College, it is the oldest institution of higher education in Cincinnati and has an annual enrollment of over 44,0 ...

(2003–2009), before being named the Arthur Russell Morgan Endowed Chair of Medicine, and Research Director of the Metabolism Center of Excellence for Diabetes and Obesity at the

(2009–2011). He was Research Director of the Helmholtz Diabetes Center and Director of the Institute for Diabetes and Obesity at

(2011–2018). Early in his career, Tschöp reported on the orexigenic, adipogenic, and metabolic effects of

ghrelin Ghrelin (; or lenomorelin, INN) is a hormone produced by enteroendocrine cells of the gastrointestinal tract, especially the stomach, and is often called a "hunger hormone" because it increases the drive to eat. Blood levels of ghrelin are hi ...

and its secretory control by nutrients, which has had a major influence on human obesity and diabetes research. His corresponding publication in ''Nature'' is among today's most frequently cited metabolism research papers. It added a fundamental pathway to the current model of body weight and glucose control and established novel drug targets for metabolic diseases. Tschöp went on to further dissect gut-brain communication pathways, based on GI-hormone signaling and lessons from unraveling the molecular underpinnings of gastric bypass surgery. Together with his close collaborator Richard DiMarchi (

Indiana University Indiana University (IU) is a system of public universities in the U.S. state of Indiana. Campuses Indiana University has two core campuses, five regional campuses, and two regional centers under the administration of IUPUI. *Indiana Universi ...

) he discovered and validated novel gut hormone co-agonist peptides, which simultaneously target several neuroendocrine receptors and efficiently reduce body weight and improve glucose tolerance. Several of these compounds are now in clinical trials for the treatment of diabetes and obesity. Tschöp and DiMarchi more recently went on to discover and validate another class of drug candidates by engineering peptide to deliver steroid/small molecules to selected cell populations. In 2022, Tschöp was a candidate to succeed

Heinz Engl Heinz Werner Engl (born 28 March 1953) is an Austrian mathematician who served as the rector of the University of Vienna. Engl was born in Linz. He studied at the Johannes Kepler University of Linz, where he earned an engineering diploma in tech ...

rector Rector (Latin for the member of a vessel's crew who steers) may refer to: Style or title *Rector (ecclesiastical), a cleric who functions as an administrative leader in some Christian denominations *Rector (academia), a senior official in an edu ...

of the

University of Vienna The University of Vienna (german: Universität Wien) is a public research university located in Vienna, Austria. It was founded by Duke Rudolph IV in 1365 and is the oldest university in the German-speaking world. With its long and rich hist ...

; however, he ultimately withdrew his application. As of January 2023, he is the vice president for health of the Helmholtz Association of German Research Centers.

Other activities

* ''

Cell Cell most often refers to: * Cell (biology), the functional basic unit of life Cell may also refer to: Locations * Monastic cell, a small room, hut, or cave in which a religious recluse lives, alternatively the small precursor of a monastery ...

'', Member of the Advisory Board (since 2020) * Institute of Metabolism and Systems Research (IMSR),

University of Birmingham The University of Birmingham (informally Birmingham University) is a Public university, public research university located in Edgbaston, Birmingham, United Kingdom. It received its royal charter in 1900 as a successor to Queen's College, Birmingha ...

, Member of the Scientific Advisory Board

Awards and recognition

* 2023: Banting Medal, American Diabetes Association * 2022:

European Association for the Study of Diabetes The European Association for the Study of Diabetes (EASD) is a scientific association founded in Montecatini Terme, Italy in 1965 with Joseph Hoet as Founding President. The aims of the association are to encourage and support research in the fiel ...

(EASD)-Lilly Centennial Anniversary Prize * 2022: Member of the

Association of American Physicians The Association of American Physicians (AAP) is an honorary medical society founded in 1885 by the Canadian physician Sir William Osler and six other distinguished physicians of his era for "the advancement of scientific and practical medicine." ...

* 2021:

Ernst Jung Prize The Ernst Jung Prize is a prize awarded annually for excellence in biomedical sciences. The Ernst Jung Foundation, funded by Hamburg merchant Ernst Jung in 1967, has awarded the Ernst Jung Prize in Medicine, now €300,000, since 1976, and the lif ...

for Medicine * 2021: Berthold Medal of the German Society for Endocrinology * 2020: Member of the

European Molecular Biology Organization The European Molecular Biology Organization (EMBO) is a professional, non-profit organization of more than 1,800 life scientists. Its goal is to promote research in life science and enable international exchange between scientists. It co-funds cour ...

(EMBO) * 2019: C. Ronald Kahn Distinguished Lectureship 2019–2020,

Joslin Diabetes Center Joslin Diabetes Center is the world's largest diabetes research center, diabetes clinic, and provider of diabetes education. It is located in the Longwood Medical and Academic Area in Boston, Massachusetts, United States. Among the Harvard Medica ...

* 2019: Paul Langerhans Medal * 2018: Carus Prize, City of Schweinfurt * 2018: Member of the Bavarian Academy of Sciences and Humanities * 2017: Carus Medal,

Academy of Sciences Leopoldina The German National Academy of Sciences Leopoldina (german: Deutsche Akademie der Naturforscher Leopoldina – Nationale Akademie der Wissenschaften), short Leopoldina, is the national academy of Germany, and is located in Halle (Saale). Founded ...

* 2017: Charles H. Best Lectureship and Award, University of Toronto * 2017: Hansen Family Award, Bayer Foundations * 2017: Honorary doctorate degree (Dr. h.c.),

University of Leipzig Leipzig University (german: Universität Leipzig), in Leipzig in Saxony, Germany, is one of the world's oldest universities and the second-oldest university (by consecutive years of existence) in Germany. The university was founded on 2 Decemb ...

* 2017: Rolf Sammet Professorship, Frankfurt University * 2017: Outstanding Innovation Award, Endocrine Society * 2017: Geoffrey Harris Prize * 2016: The Victor Mutt Award * 2016: European Medal of the Society for Endocrinology * 2016: Elected Member,

Academia Europaea The Academia Europaea is a pan-European Academy of Humanities, Letters, Law, and Sciences. The Academia was founded in 1988 as a functioning Europe-wide Academy that encompasses all fields of scholarly inquiry. It acts as co-ordinator of Europea ...

* 2016: ERC Advanced Grant * 2014: Erwin Schrödinger Prize, Stifterverband Science Award – Erwin Schrödinger Prize * 2014: Paul Martini Prize, Paul Martini Foundation * 2014: Linda and Jack Gill Distinguished Scientist Award, Linda and Jack Gill Center for Biomolecular Science at Indiana University * 2013: Elected Member, German National

* 2012: Werner-Creutzfeld-Award, German Diabetes Society * 2012: Alexander von Humboldt Professorship,

Alexander von Humboldt Foundation The Alexander von Humboldt Foundation (german: Alexander von Humboldt-Stiftung) is a foundation established by the government of the Federal Republic of Germany and funded by the Federal Foreign Office, the Federal Ministry of Education and Rese ...

* 2011: Outstanding Scientific Achievement Award, American Diabetes Association * 2010: NIH/NIDDK 60th Anniversary Scholar Award * 2010: André Mayer Award, Int. Association for the Study of Obesity, IASO * 2009: Elected Member, The American Society for Clinical Investigation, ASCI * 2007: Scientific Achievement Award,

The Obesity Society The Obesity Society is a scientific society dedicated to the study of obesity and its treatment. It was founded in 1982 and has approximately 2,500 members. The official scientific journal of the society is ''Obesity'', which is available in prin ...

, TOS/NAASO * 2007: Christina Barz Award of the German Society for Psychiatry, Neurology and Psychosomatic Medicine * 2002: Young Investigator Award, European Neuroendocrine Association, ENEA * 2001: Schoeller-Junkmann Award of the German Endocrine Society, DGE * 2000: Lilly Research Laboratories President's Award * 2000: Eli Lilly Endocrine Research Award for Science

References

External links

* * Prof. Matthias Tschöp
Chair of Metabolic Diseases, TUM School of Medicine
{{DEFAULTSORT:Tschop, Matthias H. 1967 births Living people 21st-century German scientists Members of the German National Academy of Sciences Leopoldina Members of Academia Europaea Members of the Bavarian Academy of Sciences