MON 863
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MON 863 is a genetically engineered variety of maize produced by
Monsanto The Monsanto Company () was an American agrochemical and agricultural biotechnology corporation founded in 1901 and headquartered in Creve Coeur, Missouri. Monsanto's best known product is Roundup, a glyphosate-based herbicide, developed in th ...
. It is genetically altered to express a modified version of
Cry3Bb1 Delta endotoxins (δ-endotoxins) are pore-forming toxins produced by ''Bacillus thuringiensis'' species of bacteria. They are useful for their insecticidal action and are the primary toxin produced by Bt maize/corn. During spore formation th ...
, a delta endotoxin which originates from ''
Bacillus thuringiensis ''Bacillus thuringiensis'' (or Bt) is a gram-positive, soil-dwelling bacterium, the most commonly used biological pesticide worldwide. ''B. thuringiensis'' also occurs naturally in the gut of caterpillars of various types of moths and butterflie ...
''. This protects the plant from
corn rootworm ''Diabrotica'' is a large, widespread genus of beetles in the family Chrysomelidae. Members of this genus include several destructive agricultural pest species, sometimes referred to as cucumber beetles or corn rootworms. Species * '' Diabroti ...
. Unlike
MON 810 The MON 810 corn is a genetically modified maize used around the world. It is a ''Zea mays'' line known as YieldGard from the company Monsanto.Van Rie J. et al. 1989. Specificity of Bacillius thuringiensis delta-endotoxins. Eur J Biochem 186: 239-24 ...
, Bt 11, and Bt 176 which each produce a modified Cry1Ab, MON 863 instead produces a modified Cry3Bb1 toxin and contains nptII, a
marker gene In biology, a marker gene may have several meanings. In nuclear biology and molecular biology, a marker gene is a gene used to determine if a nucleic acid sequence has been successfully inserted into an organism's DNA. In particular, there are tw ...
for
antibiotic resistance Antimicrobial resistance (AMR) occurs when microbes evolve mechanisms that protect them from the effects of antimicrobials. All classes of microbes can evolve resistance. Fungi evolve antifungal resistance. Viruses evolve antiviral resistance. ...
.


History

In 2004, Monsanto sought approval in Europe to introduce MON 863. Approval was granted in 2005 for use in feed and in 2006 for use in food. There was controversy over acceptance by regulatory bodies of industry-funded toxicity studies and over the design of those studies led by Pr
Gilles-Éric Séralini Gilles-Éric Séralini (born 23 August 1960) is a French molecular biologist, political advisor and activist on genetically modified organisms and foods. He is of Algerian-French origin. Séralini has been a professor of molecular biology at t ...
, who was on the committee that reviewed MON863 for the French government. See
Genetically modified food controversies Genetically modified food controversies are disputes over the use of foods and other goods derived from genetically modified crops instead of conventional crops, and other uses of genetic engineering in food production. The disputes involve co ...
for details of this controversy, which extended beyond MON 863. Following legal action by parties including the
Swedish Board of Agriculture The Swedish Board of Agriculture ( sv, Statens jordbruksverk, commonly known as ''Jordbruksverket'') is a Government agency in Sweden that answers to the Ministry of Agriculture. The agency headquarters is located in Jönköping. It is responsi ...
and
Greenpeace Greenpeace is an independent global campaigning network, founded in Canada in 1971 by Irving Stowe and Dorothy Stowe, immigrant environmental activists from the United States. Greenpeace states its goal is to "ensure the ability of the Earth t ...
, a
Münster Münster (; nds, Mönster) is an independent city (''Kreisfreie Stadt'') in North Rhine-Westphalia, Germany. It is in the northern part of the state and is considered to be the cultural centre of the Westphalia region. It is also a state distr ...
appeals court ruled that Monsanto would be forced to publicly reveal its research data.


Legal status

As of 2015, MON 863 is approved for cultivation in three countries: the United States, Japan, and Canada. The corn is approved for use in
Australia Australia, officially the Commonwealth of Australia, is a Sovereign state, sovereign country comprising the mainland of the Australia (continent), Australian continent, the island of Tasmania, and numerous List of islands of Australia, sma ...
,
Canada Canada is a country in North America. Its ten provinces and three territories extend from the Atlantic Ocean to the Pacific Ocean and northward into the Arctic Ocean, covering over , making it the world's second-largest country by tot ...
,
China China, officially the People's Republic of China (PRC), is a country in East Asia. It is the world's most populous country, with a population exceeding 1.4 billion, slightly ahead of India. China spans the equivalent of five time zones and ...
, the
European Union The European Union (EU) is a supranational political and economic union of member states that are located primarily in Europe. The union has a total area of and an estimated total population of about 447million. The EU has often been des ...
,
Japan Japan ( ja, 日本, or , and formally , ''Nihonkoku'') is an island country in East Asia. It is situated in the northwest Pacific Ocean, and is bordered on the west by the Sea of Japan, while extending from the Sea of Okhotsk in the north ...
,
Mexico Mexico (Spanish: México), officially the United Mexican States, is a country in the southern portion of North America. It is bordered to the north by the United States; to the south and west by the Pacific Ocean; to the southeast by Guatema ...
,
New Zealand New Zealand ( mi, Aotearoa ) is an island country in the southwestern Pacific Ocean. It consists of two main landmasses—the North Island () and the South Island ()—and over 700 smaller islands. It is the sixth-largest island count ...
,
Russia Russia (, , ), or the Russian Federation, is a List of transcontinental countries, transcontinental country spanning Eastern Europe and North Asia, Northern Asia. It is the List of countries and dependencies by area, largest country in the ...
,
Singapore Singapore (), officially the Republic of Singapore, is a sovereign island country and city-state in maritime Southeast Asia. It lies about one degree of latitude () north of the equator, off the southern tip of the Malay Peninsula, borde ...
,
South Korea South Korea, officially the Republic of Korea (ROK), is a country in East Asia, constituting the southern part of the Korea, Korean Peninsula and sharing a Korean Demilitarized Zone, land border with North Korea. Its western border is formed ...
,
Taiwan Taiwan, officially the Republic of China (ROC), is a country in East Asia, at the junction of the East and South China Seas in the northwestern Pacific Ocean, with the People's Republic of China (PRC) to the northwest, Japan to the nort ...
, and the
United States The United States of America (U.S.A. or USA), commonly known as the United States (U.S. or US) or America, is a country primarily located in North America. It consists of 50 states, a federal district, five major unincorporated territorie ...
.Staff, ISAAA. Last updated July 27, 201
Event Name: MON863
See Authorizations tab. Accessed June 2, 2016


See also

*
MON 810 The MON 810 corn is a genetically modified maize used around the world. It is a ''Zea mays'' line known as YieldGard from the company Monsanto.Van Rie J. et al. 1989. Specificity of Bacillius thuringiensis delta-endotoxins. Eur J Biochem 186: 239-24 ...


References

{{DEFAULTSORT:Mon 863 Genetically modified maize Monsanto