Motor neuron and pancreas homeobox 1 (MNX1), also known as Homeobox HB9 (HLXB9), is a human
protein
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, res ...
encoded by the ''MNX1''
gene
In biology, the word gene (from , ; "... Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' or ''birth'' or ''gender'') can have several different meanings. The Mendelian gene is a b ...
.
Clinical significance
Mutations in the ''MNX1'' gene are associated with
Currarino syndrome.
Upregulated expression of MNX1-AS1 long noncoding RNA predicts poor prognosis in gastric cancer.
[ Zhang, W., Huang, L., Lu, X., Wang, K., Ning, X., & Liu, Z. (2019). Upregulated expression of MNX1-AS1 long noncoding RNA predicts poor prognosis in gastric cancer. Bosnian journal of basic medical sciences, 19(2), 164–171. https://doi.org/10.17305/bjbms.2019.3713 ]
References
Further reading
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External links
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Transcription factors
{{gene-7-stub