Lumír Ondřej Hanuš
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Lumír Ondřej Hanuš ( he, לומיר הנוש) is a
Czech Czech may refer to: * Anything from or related to the Czech Republic, a country in Europe ** Czech language ** Czechs, the people of the area ** Czech culture ** Czech cuisine * One of three mythical brothers, Lech, Czech, and Rus' Places * Czech, ...
analytic chemist and leading authority in the field of cannabis research. In 1992, he and William Anthony Devane isolated and first described the structure of
anandamide Anandamide (ANA), also known as ''N''-arachidonoylethanolamine (AEA), is a fatty acid neurotransmitter. Anandamide was the first endocannabinoid to be discovered: it participates in the body's endocannabinoid system by binding to cannabinoid r ...
, an endogenous
cannabinoid Cannabinoids () are several structural classes of compounds found in the cannabis plant primarily and most animal organisms (although insects lack such receptors) or as synthetic compounds. The most notable cannabinoid is the phytocannabinoid tet ...
neurotransmitter A neurotransmitter is a signaling molecule secreted by a neuron to affect another cell across a synapse. The cell receiving the signal, any main body part or target cell, may be another neuron, but could also be a gland or muscle cell. Neu ...
.


Biography

Lumír Hanuš was born in 1947 in
Olomouc Olomouc (, , ; german: Olmütz; pl, Ołomuniec ; la, Olomucium or ''Iuliomontium'') is a city in the Czech Republic. It has about 99,000 inhabitants, and its larger urban zone has a population of about 384,000 inhabitants (2019). Located on t ...
, in what was then
Czechoslovakia , rue, Чеськословеньско, , yi, טשעכאסלאוואקיי, , common_name = Czechoslovakia , life_span = 1918–19391945–1992 , p1 = Austria-Hungary , image_p1 ...
. He is a distant relative of Czech chemist Josef Hanuš (1872–1955).


Academic career

In 1966, Hanuš began studying at the Faculty of Science of
Palacký University Olomouc Palacký University Olomouc is the oldest university in Moravia and the second-oldest in the Czech Republic. It was established in 1573 as a public university led by the Jesuit order in Olomouc, which was at that time the capital of Moravia an ...
. In 1970, professor Zdeněk Krejčí of the
Faculty of Medicine A medical school is a tertiary educational institution, or part of such an institution, that teaches medicine, and awards a professional degree for physicians. Such medical degrees include the Bachelor of Medicine, Bachelor of Surgery (MBBS, M ...
's Department of Hygiene and Epidemiology (where the anti-bacterial effects of cannabis were described in 1955) needed an aide. Hanuš started to work as Krejčí's assistant in the research of cannabis and hashish in December of that year. There, Hanuš also met professors Jan Kabelík and František Šantavý, who, together with Krejčí, laid the foundations of the research of cannabis and its curative effects. Hanuš grew cannabis for research purposes on two fields in the Research Institute of Vegetable Growing and Breeding in Olomouc from 1971. The extracts were also used at the University Hospital Olomouc as a cure for
aphthous ulcer Aphthous stomatitis, or recurrent aphthous stomatitis (RAS), is a common condition characterized by the repeated formation of benign and non-contagious mouth ulcers (aphthae) in otherwise healthy individuals. The informal term ''canker sore'' i ...
,
herpes simplex Herpes simplex is a viral infection caused by the herpes simplex virus. Infections are categorized based on the part of the body infected. Oral herpes involves the face or mouth. It may result in small blisters in groups often called col ...
,
herpes zoster Shingles, also known as zoster or herpes zoster, is a viral disease characterized by a painful skin rash with blisters in a localized area. Typically the rash occurs in a single, wide mark either on the left or right side of the body or fac ...
, and pressure ulcers. Hanuš graduated with a Master of Science in 1972 and he earned a Doctorate in Science at Olomouc in 1974. He pursued his academic and research activities there until 1990. Hanuš also took part in research at the
Czechoslovak Academy of Sciences The Czechoslovak Academy of Sciences (Czech: ''Československá akademie věd'', Slovak: ''Česko-slovenská akadémia vied'') was established in 1953 to be the scientific center for Czechoslovakia. It was succeeded by the Czech Academy of Scienc ...
and continued post-graduate research study at Jan Evangelista Purkyně University in
Brno Brno ( , ; german: Brünn ) is a city in the South Moravian Region of the Czech Republic. Located at the confluence of the Svitava and Svratka rivers, Brno has about 380,000 inhabitants, making it the second-largest city in the Czech Republic ...
(today
Masaryk University Masaryk University (MU) ( cs, Masarykova univerzita; la, Universitas Masarykiana Brunensis) is the second largest university in the Czech Republic, a member of the Compostela Group and the Utrecht Network. Founded in 1919 in Brno as the se ...
). In years 1978–1979 he worked as a research associate at the
University of Mississippi The University of Mississippi ( byname Ole Miss) is a public research university that is located adjacent to Oxford, Mississippi, and has a medical center in Jackson. It is Mississippi's oldest public university and its largest by enrollment ...
, focusing not only on cannabis, but also on coca leaves. He became
associate professor Associate professor is an academic title with two principal meanings: in the North American system and that of the ''Commonwealth system''. Overview In the '' North American system'', used in the United States and many other countries, it is ...
in organic chemistry in Olomouc in 1994 and obtained a Doctorate of Sciences in pharmaceutical chemistry at
Charles University ) , image_name = Carolinum_Logo.svg , image_size = 200px , established = , type = Public, Ancient , budget = 8.9 billion CZK , rector = Milena Králíčková , faculty = 4,057 , administrative_staff = 4,026 , students = 51,438 , under ...
in 1995. Hanuš was for many years in contact with Israeli cannabis researcher
Raphael Mechoulam Raphael Mechoulam ( he, רפאל משולם, bg, Рафаел Мешулам; born 5 November 1930) is an Israeli organic chemist and professor of Medicinal Chemistry at the Hebrew University of Jerusalem in Israel. Mechoulam is best known for h ...
by letter. Following the
Velvet Revolution The Velvet Revolution ( cs, Sametová revoluce) or Gentle Revolution ( sk, Nežná revolúcia) was a non-violent transition of power in what was then Czechoslovakia, occurring from 17 November to 28 November 1989. Popular demonstrations agains ...
, Hanuš was invited to continue his research at
Hebrew University of Jerusalem The Hebrew University of Jerusalem (HUJI; he, הַאוּנִיבֶרְסִיטָה הַעִבְרִית בִּירוּשָׁלַיִם) is a public research university based in Jerusalem, Israel. Co-founded by Albert Einstein and Dr. Chaim Weiz ...
in
Israel Israel (; he, יִשְׂרָאֵל, ; ar, إِسْرَائِيل, ), officially the State of Israel ( he, מְדִינַת יִשְׂרָאֵל, label=none, translit=Medīnat Yīsrāʾēl; ), is a country in Western Asia. It is situated ...
. In Israel, Hanuš and American molecular pharmacologist William Anthony Devane in 1992 first described the structure of
Anandamide Anandamide (ANA), also known as ''N''-arachidonoylethanolamine (AEA), is a fatty acid neurotransmitter. Anandamide was the first endocannabinoid to be discovered: it participates in the body's endocannabinoid system by binding to cannabinoid r ...
, an endogenous
cannabinoid Cannabinoids () are several structural classes of compounds found in the cannabis plant primarily and most animal organisms (although insects lack such receptors) or as synthetic compounds. The most notable cannabinoid is the phytocannabinoid tet ...
neurotransmitter A neurotransmitter is a signaling molecule secreted by a neuron to affect another cell across a synapse. The cell receiving the signal, any main body part or target cell, may be another neuron, but could also be a gland or muscle cell. Neu ...
. Hanuš continues his research in Jerusalem on cannabinoids, endocannabinoids and their derivatives.


Views on cannabis

Hanuš marks cannabis as "one of the safest known medications". According to Hanuš, alcohol and tobacco should be "blacklisted" rather than cannabis, as there is a possibility of both physical and psychological addiction to the first two, while there is no possibility of physical, and only limited possibility of psychological addiction to marijuana. Moreover, people under the influence of marijuana are not dangerous to others. He does not support smoking marijuana because of the dangers of smoke inhalation. Hanuš is against uncontrolled use of marijuana, but he fully supports its use for medical purposes. In April 2010 and September 2011, Hanuš took part in a seminar of the
Czech Parliament The Parliament of the Czech Republic ( cs, Parlament České republiky) or just Parliament ( cs, Parlament) is the legislative body of the Czech Republic, seated in Malá Strana, Prague. It consists of two chambers, both elected in direct elec ...
aimed at introduction of cannabinoid treatment.


Awards

* September 14, 2005: Hanuš Medal (The Czech Chemical Society in Prague) for furthering creditable work in the fields of chemistry. * November 6, 2006: Memorial Medal (Rector of the
Palacký University Olomouc Palacký University Olomouc is the oldest university in Moravia and the second-oldest in the Czech Republic. It was established in 1573 as a public university led by the Jesuit order in Olomouc, which was at that time the capital of Moravia an ...
) on the 50th anniversary of the revival and reopening of the university in
Olomouc Olomouc (, , ; german: Olmütz; pl, Ołomuniec ; la, Olomucium or ''Iuliomontium'') is a city in the Czech Republic. It has about 99,000 inhabitants, and its larger urban zone has a population of about 384,000 inhabitants (2019). Located on t ...
at the occasion of delivering the 13th annual lecture in honour of J. L. Fischer * April 12, 2007:
Doctor honoris causa An honorary degree is an academic degree for which a university (or other degree-awarding institution) has waived all of the usual requirements. It is also known by the Latin phrases ''honoris causa'' ("for the sake of the honour") or ''ad ho ...
(
Masaryk University Masaryk University (MU) ( cs, Masarykova univerzita; la, Universitas Masarykiana Brunensis) is the second largest university in the Czech Republic, a member of the Compostela Group and the Utrecht Network. Founded in 1919 in Brno as the se ...
in
Brno Brno ( , ; german: Brünn ) is a city in the South Moravian Region of the Czech Republic. Located at the confluence of the Svitava and Svratka rivers, Brno has about 380,000 inhabitants, making it the second-largest city in the Czech Republic ...
) * 2009: nominated for the National Award of the Czech Government "Czech Mind" ("Česká hlava") * 2010: nominated for the Patria Award of the Czech Government "Czech Mind" ("Česká hlava") * 2010: nominated for The 2010 Jack Herer Award for Outstanding Hemp Awareness in the field of Medicine * April 26, 2010: Outstanding Immigrant Scientist (1990–2010) for his contribution to the State of
Israel Israel (; he, יִשְׂרָאֵל, ; ar, إِسْرَائِيل, ), officially the State of Israel ( he, מְדִינַת יִשְׂרָאֵל, label=none, translit=Medīnat Yīsrāʾēl; ), is a country in Western Asia. It is situated ...
, Ministry of Immigrant Absorption, Israel * May 4, 2011:
Doctor honoris causa An honorary degree is an academic degree for which a university (or other degree-awarding institution) has waived all of the usual requirements. It is also known by the Latin phrases ''honoris causa'' ("for the sake of the honour") or ''ad ho ...
(
Palacký University Olomouc Palacký University Olomouc is the oldest university in Moravia and the second-oldest in the Czech Republic. It was established in 1573 as a public university led by the Jesuit order in Olomouc, which was at that time the capital of Moravia an ...
) * 2011: Honorary Scientific Fellow of the Czech Neuropsychopharmacological Society * 2011: nominated for the Addictology award for best achievement in the year 2011 * November 22, 2012: Addictology Award (Charles University, Prague) for significant contribution in the field of addictology in the past year * June 13, 2013: Olomouc City Award for the year 2012 * March 29, 2014: Recognition (ONEJ), Ljubljana, Slovenia * 2014: nominated for the position of The International Cannabinoid Research Society President * March 22, 2016: 2015 Lifetime Award Winner (Americans for Safe Access), Washington D.C., USA * September 10, 2016: Commemorative Medal of the Palacky University in Olomouc for extraordinary representation of Palacky University in the Czech Republic and abroad (Pamětní medaile Univerzity Palackého v Olomouci za mimořádnou reprezentaci Univerzity Palackého v České republice a v zahraničí) * January 13, 2018: Recognition, Punta del Este, Uruguay * September 27, 2018: Lifetime Achievement Award, CanEx Jamaica, Montego Bay, Jamaica


See also

*
Anandamide Anandamide (ANA), also known as ''N''-arachidonoylethanolamine (AEA), is a fatty acid neurotransmitter. Anandamide was the first endocannabinoid to be discovered: it participates in the body's endocannabinoid system by binding to cannabinoid r ...
*
2-Arachidonyl glyceryl ether 2-Arachidonyl glyceryl ether (2-AGE, Noladin ether) is a putative endocannabinoid discovered by Lumír Hanuš and colleagues at the Hebrew University of Jerusalem, Israel. It is an ether formed from the alcohol analog of arachidonic acid and gl ...
*
Medical cannabis Medical cannabis, or medical marijuana (MMJ), is cannabis and cannabinoids that are prescribed by physicians for their patients. The use of cannabis as medicine has not been rigorously tested due to production and governmental restriction ...


References


External links


Dr. Lumir Hanus
Hebrew University of Jerusalem – Faculty of Medicine * in
Moravia Moravia ( , also , ; cs, Morava ; german: link=yes, Mähren ; pl, Morawy ; szl, Morawa; la, Moravia) is a historical region in the east of the Czech Republic and one of three historical Czech lands, with Bohemia and Czech Silesia. The ...
n dialect {{DEFAULTSORT:Hanus, Lumir Ondrej 1947 births Czech chemists Living people Czech scientists Palacký University Olomouc alumni Masaryk University alumni Cannabis in the Czech Republic Hebrew University of Jerusalem faculty