John Hughes Bennett
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John Hughes Bennett PRCPE FRSE (31 August 1812 – 25 September 1875) was an English physician, physiologist and
pathologist Pathology is the study of the causes and effects of disease or injury. The word ''pathology'' also refers to the study of disease in general, incorporating a wide range of biology research fields and medical practices. However, when used in t ...
. His main contribution to medicine has been the first description of
leukemia Leukemia ( also spelled leukaemia and pronounced ) is a group of blood cancers that usually begin in the bone marrow and result in high numbers of abnormal blood cells. These blood cells are not fully developed and are called ''blasts'' or ...
as a
blood disorder Hematologic diseases are disorders which primarily affect the blood & blood-forming organs. Hematologic diseases include rare genetic disorders, anemia, HIV, sickle cell disease & complications from chemotherapy or transfusions. Myeloid * Hemog ...
(1845). The first person to describe leukemia as an unknown disease was
Alfred François Donné Alfred François Donné (13 September 1801 – 7 March 1878) was a French bacteriologist and doctor. He was born in Noyon, France, and died in Paris. Donné was the discoverer of Trichomonas vaginalis. He was also the inventor of the photomicro ...
. Bennett was the first doctor to describe aspergillosis. In his seminal paper published in 1842 entitled "On the parasitic vegetable structures found growing in living animals" he makes the very first description of ''
Aspergillus ' () is a genus consisting of several hundred mold species found in various climates worldwide. ''Aspergillus'' was first catalogued in 1729 by the Italian priest and biologist Pier Antonio Micheli. Viewing the fungi under a microscope, Mic ...
'' (a pathogenic fungus) growing in the lung tissue of humans.


Biography

Born in London, he was educated at Mount Radford School in Exeter, and being destined for the medical profession he entered an apprenticeship with Mr Sedgwick, a surgeon in
Maidstone Maidstone is the largest town in Kent, England, of which it is the county town. Maidstone is historically important and lies 32 miles (51 km) east-south-east of London. The River Medway runs through the centre of the town, linking it wi ...
. In 1833 he began his studies at
Edinburgh Edinburgh ( ; gd, Dùn Èideann ) is the capital city of Scotland and one of its 32 council areas. Historically part of the county of Midlothian (interchangeably Edinburghshire before 1921), it is located in Lothian on the southern shore of t ...
, and in 1837 graduated with the highest honours and a gold medal, with a dissertation entitled ''The Physiology and Pathology of the Brain''. During his last year at Edinburgh he was elected President of the Royal Medical Society,
Royal Physical Society of Edinburgh The Royal Physical Society of Edinburgh was a learned society based in Edinburgh, Scotland "for the cultivation of the physical sciences". The society was founded in 1771 as the Physico-Chirurgical Society but soon after changed its name to the ...
, and a vice-president of the Anatomical and Physiological Society. During the next two years he studied in Paris (where he founded the English-speaking Medical Society) and then spent two in Germany (mainly at Heidelberg and the Charité Hospital in Berlin), before returning to Edinburgh in 1841 where he published a ''Treatise on Cod-liver Oil as a Therapeutic Agent''. In the same year he began to lecture as an extra-academical teacher on
histology Histology, also known as microscopic anatomy or microanatomy, is the branch of biology which studies the microscopic anatomy of biological tissues. Histology is the microscopic counterpart to gross anatomy, which looks at larger structures vi ...
, drawing attention to the importance of the
microscope A microscope () is a laboratory instrument used to examine objects that are too small to be seen by the naked eye. Microscopy is the science of investigating small objects and structures using a microscope. Microscopic means being invisi ...
in the investigation of disease; and as physician to the
Royal Public Dispensary of Edinburgh The Public Dispensary of Edinburgh was the first free-of-charge hospital in Scotland. History Edinburgh has a history of providing free medical care to the poor. In first meeting of the Royal College of Physicians of Edinburgh, in 1681, the ...
he instituted courses of polyclinical medicine. In 1843 he was elected a Fellow of the Royal Society of Edinburgh his proposer being Sir
Robert Christison Sir Robert Christison, 1st Baronet, (18 July 1797 – 27 January 1882) was a Scottish toxicologist and physician who served as president of the Royal College of Physicians of Edinburgh (1838–40 and 1846-8) and as president of the British ...
. His address was then listed as 1 Glenfinlas Street, just off
Charlotte Square 300px, Robert Adam's palace-fronted north side Charlotte Square is a garden square in Edinburgh, Scotland, part of the New Town, designated a UNESCO World Heritage Site. The square is located at the west end of George Street and was intend ...
. In the same year he was appointed professor of the Institutes of Medicine at Edinburgh, and performed the duties of that chair with great energy until incapacitated by failing health, in 1874. In 1845, Bennett published a paper entitled a ''Case of Hypertrophy of the Spleen and Liver in which Death Took Place from Suppuration of the Blood'', the first recorded case of
leukemia Leukemia ( also spelled leukaemia and pronounced ) is a group of blood cancers that usually begin in the bone marrow and result in high numbers of abnormal blood cells. These blood cells are not fully developed and are called ''blasts'' or ...
, then known as
leucocythemia Acute myeloid leukemia (AML) is a cancer of the myeloid line of blood cells, characterized by the rapid growth of abnormal cells that build up in the bone marrow and blood and interfere with normal blood cell production. Symptoms may include ...
, in the ''Edinburgh Medical and Surgical Journal''. In 1849, Bennett was elected as a member to the
American Philosophical Society The American Philosophical Society (APS), founded in 1743 in Philadelphia, is a scholarly organization that promotes knowledge in the sciences and humanities through research, professional meetings, publications, library resources, and communit ...
. In 1855 he was a prime opponent of Thomas Laycock for the Edinburgh Chair. His obituary refers to this as an "exciting contest". Michalel Barfoot wrote in 1995 that in fact extremely bitter, and became a source of great dissension in subsequent years. Barfoot describes him as having "the personality biographers' dreams are made of", and quotes Bennett's biographer
John M'Kendrick John is a common English name and surname: * John (given name) * John (surname) John may also refer to: New Testament Works * Gospel of John, a title often shortened to John * First Epistle of John, often shortened to 1 John * Second ...
as stating that Bennett "regarded his defeat (by Laycock) as the great disappointment of his life, and there is little doubt that it tended to a certain extent to distort his views of men an things". In 1859 he was elected President of the Harveian Society. In 1873, he was elected a member of the French Academy of Medicine and granted recognition by the French government to practice medicine in France. In August 1875 he was able to be present at the meeting of the British Medical Association in Edinburgh, on which occasion he received the degree of LL.D., but the fatigue he then underwent brought on a relapse, and he was compelled to have the operation of
lithotomy Lithotomy from Greek for "lithos" (stone) and "tomos" ( cut), is a surgical method for removal of calculi, stones formed inside certain organs, such as the urinary tract (kidney stones), bladder ( bladder stones), and gallbladder (gallstones), ...
performed. He sank rapidly and died on 25 September 1875 at
Norwich Norwich () is a cathedral city and district of Norfolk, England, of which it is the county town. Norwich is by the River Wensum, about north-east of London, north of Ipswich and east of Peterborough. As the seat of the See of Norwich, with ...
. Bennett died at
Norwich Norwich () is a cathedral city and district of Norfolk, England, of which it is the county town. Norwich is by the River Wensum, about north-east of London, north of Ipswich and east of Peterborough. As the seat of the See of Norwich, with ...
on 25 September 1875, nine days after an operation for stone, performed by Mr. Cadge, from which his enfeebled strength did not enable him to recover. He was buried in the Dean Cemetery, Edinburgh, on 30 September by the side of his friends Goodsir and Edward Forbes.


Works

His publications were very numerous including ''Lectures on Clinical Medicine'' (1850–1856), which in second and subsequent editions were calle
''Clinical Lectures on the Principles and Practice of Medicine''
and were translated into various languages, including Russian and
Hindi Hindi ( Devanāgarī: or , ), or more precisely Modern Standard Hindi (Devanagari: ), is an Indo-Aryan language spoken chiefly in the Hindi Belt region encompassing parts of northern, central, eastern, and western India. Hindi has been ...
; ''Leucocythaemia'' (1852), the first recorded cure of which was published by him in 1845; ''Outlines of Physiology'' (1858), reprinted from the 8th edition of the ''
Encyclopædia Britannica The (Latin for "British Encyclopædia") is a general knowledge English-language encyclopaedia. It is published by Encyclopædia Britannica, Inc.; the company has existed since the 18th century, although it has changed ownership various t ...
'', ''Pathology and Treatment of Pulmonary
Tuberculosis Tuberculosis (TB) is an infectious disease usually caused by '' Mycobacterium tuberculosis'' (MTB) bacteria. Tuberculosis generally affects the lungs, but it can also affect other parts of the body. Most infections show no symptoms, i ...
'' (1853); ''Textbook of Physiology'' (1871–1872). Because Bennett introduced practical classes in the teaching of physiology, he is considered the father of physiological education in medical schools. He was also the first to teach the clinical use of the microscope systematically and its uses in the teaching of pathology and physiology. He opposed
bloodletting Bloodletting (or blood-letting) is the withdrawal of blood from a patient to prevent or cure illness and disease. Bloodletting, whether by a physician or by leeches, was based on an ancient system of medicine in which blood and other bodily flu ...
and was highly influential in changing medical therapeutics towards a more science-based approach in the second half of the 19th century. He supported the admission of women to medical schools and advocated a better interaction between medical specialities.


Memorials

In 1901, the
University of Edinburgh The University of Edinburgh ( sco, University o Edinburgh, gd, Oilthigh Dhùn Èideann; abbreviated as ''Edin.'' in post-nominals) is a public research university based in Edinburgh, Scotland. Granted a royal charter by King James VI in 15 ...
inaugurated the ''John Hughes Bennett Laboratory of Experimental Pathology'', in homage to "one of that galaxy of talent and genius that illuminated Edinburgh in the middle decades of the last century". A second laboratory with his name was opened in 1998, in a joint venture between Britain's Leukaemia Research Fund, the University of Edinburgh and the Western General Hospital Trust.


Family

On 22 August 1844 Bennett married Jessie Samuel (1824–1906), a niece of the Reverend Alexander Simpson (later moderator of the Church of Scotland). They had a son Dr Alexander Hughes Bennett (1848-1901) who became a consultant neurologist in
London London is the capital and List of urban areas in the United Kingdom, largest city of England and the United Kingdom, with a population of just under 9 million. It stands on the River Thames in south-east England at the head of a estuary dow ...
and four daughters. Their daughter Harriet Sophia Bennett (1850-1905), married Robert Cox MP.


Freemasonry

Rhind was a Scottish Freemason. He was Initiated in Lodge Canongate Kilwinning, No. 2, on 23 November 1836.History of the Lodge Canongate Kilwinning, No.2, compiled from the records 1677-1888
By Alan MacKenzie. 1888. P.238.


Notes


References

* * * * Attribution * *


Further reading

* * * *


External links


Lodge Canongate Kilwinning, No. 2 (Edinburgh)
{{DEFAULTSORT:Bennett, John Hughes 1812 births 1875 deaths Alumni of the University of Edinburgh British pathologists Scottish Freemasons 19th-century English medical doctors