James Murray (physician)
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Sir James Murray (1788–1871) was an Irish physician, whose research into digestion led to his discovery of the stomach aid Milk of Magnesia in 1809. He later studied in
electrotherapy Electrotherapy is the use of electrical energy as a medical treatment. In medicine, the term ''electrotherapy'' can apply to a variety of treatments, including the use of electrical devices such as deep brain stimulators for neurological dise ...
and led the research into the causes of cholera and other epidemics as a result of exposure to natural electricity. He was the first physician to recommend the breathing in of iodine in water vapour for respiratory diseases. Born in Derry, Murray became a licentiate in
midwifery Midwifery is the health science and health profession that deals with pregnancy, childbirth, and the postpartum period (including care of the newborn), in addition to the sexual and reproductive health of women throughout their lives. In many ...
having studied at the Edinburgh College of Surgeons in 1807. He undertook studies in pharmaceuticals, an area in which he became competent. In 1809 he developed the foundations of fluid magnesia, which contained a base ingredient of
magnesium sulfate Magnesium sulfate or magnesium sulphate (in English-speaking countries other than the US) is a chemical compound, a salt with the formula , consisting of magnesium cations (20.19% by mass) and sulfate anions . It is a white crystalline solid, ...
. He modified it for it to act as an aid for "weak nerves", low fever, spasms, cholera, and
diarrhoea Diarrhea, also spelled diarrhoea, is the condition of having at least three loose, liquid, or watery bowel movements each day. It often lasts for a few days and can result in dehydration due to fluid loss. Signs of dehydration often begin wi ...
. He named his recipe Fluid Magnesia, and set up the company Sir James Murray & Son to successfully market it. Murray graduated from the
University of Edinburgh The University of Edinburgh ( sco, University o Edinburgh, gd, Oilthigh Dhùn Èideann; abbreviated as ''Edin.'' in post-nominals) is a public research university based in Edinburgh, Scotland. Granted a royal charter by King James VI in 15 ...
as a
Doctor of Medicine Doctor of Medicine (abbreviated M.D., from the Latin ''Medicinae Doctor'') is a medical degree, the meaning of which varies between different jurisdictions. In the United States, and some other countries, the M.D. denotes a professional degree. T ...
in 1829, and became the resident physician to Henry Paget, 1st Marquess of Anglesey, in 1831, a post Murray held until the 1840s. Murray was
knight A knight is a person granted an honorary title of knighthood by a head of state (including the Pope) or representative for service to the monarch, the church or the country, especially in a military capacity. Knighthood finds origins in the Gr ...
ed in 1833 and received an honorary degree in medicine from Dublin University the following year. He was appointed as an inspector of anatomical schools in Ireland, and was a member of the central board of health, as well as the resident physician to the Netterville Dispensary and the Anglesey Lying-In Hospital,
Dublin Dublin (; , or ) is the capital and largest city of Ireland. On a bay at the mouth of the River Liffey, it is in the province of Leinster, bordered on the south by the Dublin Mountains, a part of the Wicklow Mountains range. At the 2016 c ...
. Murray died at his home in Dublin on 8 December 1871. He is the great-grandfather of the English actor
Michael Hordern Sir Michael Murray Hordern Commander of the Order of the British Empire, CBE (3 October 19112 May 1995)Morley, Sheridan"Hordern, Michael Murray (1911–1995)" ''Oxford Dictionary of National Biography'', Oxford University Press, 2004, online e ...
.


Biography


Early life and education

Murray was born in Derry to Edward Murray and his wife, Belinda née Powell. James attended the Edinburgh College of Surgeons where he became a licentiate in midwifery in 1807. There, and after hearing lectures by the English
chemist A chemist (from Greek ''chēm(ía)'' alchemy; replacing ''chymist'' from Medieval Latin ''alchemist'') is a scientist trained in the study of chemistry. Chemists study the composition of matter and its properties. Chemists carefully describe t ...
,
physicist A physicist is a scientist who specializes in the field of physics, which encompasses the interactions of matter and energy at all length and time scales in the physical universe. Physicists generally are interested in the root or ultimate cau ...
, and
meteorologist A meteorologist is a scientist who studies and works in the field of meteorology aiming to understand or predict Earth's atmospheric phenomena including the weather. Those who study meteorological phenomena are meteorologists in research, while t ...
, John Dalton, Murray undertook studies to establish the "exact proportions of heat, or electricity, naturally belonging to ... living atoms, in a state of health". After receiving his qualification, Murray was appointed the resident medical officer at a hospital in
Belfast Belfast ( , ; from ga, Béal Feirste , meaning 'mouth of the sand-bank ford') is the capital and largest city of Northern Ireland, standing on the banks of the River Lagan on the east coast. It is the 12th-largest city in the United Kingdom ...
. His career flourished under the hospital's
patron Patronage is the support, encouragement, privilege, or financial aid that an organization or individual bestows on another. In the history of art, arts patronage refers to the support that kings, popes, and the wealthy have provided to artists su ...
,
George Chichester, 3rd Marquess of Donegall George Hamilton Chichester, 3rd Marquess of Donegall (10 February 1797 – 20 October 1883), styled Viscount Chichester until 1799 and Earl of Belfast between 1799 and 1844, was an Anglo-Irish landowner, courtier and politician. He served as V ...
, who owned
Belfast Castle Belfast Castle (Irish: ''Caisleán Bhéal Feirste''Ireland Highlights: Belfast Castle. https://www.irelandhighlights.com/info/belfast-castle/ ) is a mansion located in Cave Hill Country Park in Belfast, Northern Ireland, in a prominent positio ...
.Hines-Davenport, Richard.
"Murray, Sir James (1788–1871)"
''Oxford Dictionary of National Biography'', Oxford University Press, 2004, online edition, January 2016. Retrieved 27 January 2016


Milk of Magnesia

In around 1809 Murray developed the foundations of fluid magnesia, which was widely promoted as a stomach aid. Its base ingredient,
Magnesium sulfate Magnesium sulfate or magnesium sulphate (in English-speaking countries other than the US) is a chemical compound, a salt with the formula , consisting of magnesium cations (20.19% by mass) and sulfate anions . It is a white crystalline solid, ...
, had long been known for its benefits in digestion and as an aid for
constipation Constipation is a bowel dysfunction that makes bowel movements infrequent or hard to pass. The stool is often hard and dry. Other symptoms may include abdominal pain, bloating, and feeling as if one has not completely passed the bowel movement ...
. Murray named his recipe Fluid Magnesia, and set up the company Sir James Murray & Son to successfully market it. Fluid Magnesia was later sold as a solution and recommended as a palatable
laxative Laxatives, purgatives, or aperients are substances that loosen stools and increase bowel movements. They are used to treat and prevent constipation. Laxatives vary as to how they work and the side effects they may have. Certain stimulant, lubri ...
and as a remedy for
acidity In computer science, ACID ( atomicity, consistency, isolation, durability) is a set of properties of database transactions intended to guarantee data validity despite errors, power failures, and other mishaps. In the context of databases, a ...
,
indigestion Indigestion, also known as dyspepsia or upset stomach, is a condition of impaired digestion. Symptoms may include upper abdominal fullness, heartburn, nausea, belching, or upper abdominal pain. People may also experience feeling full earlier t ...
,
heartburn Heartburn, also known as pyrosis, cardialgia or acid indigestion, is a burning sensation in the central chest or upper central abdomen. Heartburn is usually due to regurgitation of gastric acid (gastric reflux) into the esophagus. It is the m ...
, and
gout Gout ( ) is a form of inflammatory arthritis characterized by recurrent attacks of a red, tender, hot and swollen joint, caused by deposition of monosodium urate monohydrate crystals. Pain typically comes on rapidly, reaching maximal intens ...
. Along with this, Murray also developed a sweet-tasting mixture in the form of
syrup In cooking, a syrup (less commonly sirup; from ar, شراب; , beverage, wine and la, sirupus) is a condiment that is a thick, viscous liquid consisting primarily of a solution of sugar in water, containing a large amount of dissolved sugars ...
which was designed to mix in with the fluid. This gave the mixture a pleasant aftertaste, which appealed to women and child patients. He also marketed Sir James Murray's Pure Fluid Camphor, a tonic which was used to aid weak nerves, low fever, spasms, cholera, and
diarrhoea Diarrhea, also spelled diarrhoea, is the condition of having at least three loose, liquid, or watery bowel movements each day. It often lasts for a few days and can result in dehydration due to fluid loss. Signs of dehydration often begin wi ...
. Murray's innovations drew criticisms from contemporaries who thought that he had descended into commerce. Murray never patented his formula internationally, only protecting its rights in the British Empire and its colonies. This left him susceptible to imposters and he was forced to protect his business by litigation after his rights were infringed on several occasions. Because of its restriction to the British Empire, Murray's assistant, Dinnisford, became wealthy after he popularised the formula after Murray's death.


Superphosphate fertiliser

James Murray was also interested in the development of fertilizers for use in agriculture. Murray took out patents covering superphosphate fertiliser on 23 May 1842. On the same day
John Bennet Lawes Sir John Bennet Lawes, 1st Baronet, FRS (28 December 1814 – 31 August 1900) was an English entrepreneur and agricultural scientist. He founded an experimental farm at his home at Rothamsted Manor that eventually became Rothamsted Research, ...
also took out a superphosphate patent. Murray was judged to have the priority patent as he had been working on superphosphate since 1808. Superphosphate is a soluble form of phosphate rock which makes phosphate available to plants.


Honours

Murray graduated as a
Doctor of Medicine Doctor of Medicine (abbreviated M.D., from the Latin ''Medicinae Doctor'') is a medical degree, the meaning of which varies between different jurisdictions. In the United States, and some other countries, the M.D. denotes a professional degree. T ...
at the University of Edinburgh in 1829, and became the resident physician to the lord lieutenant of Ireland, Henry Paget, 1st Marquess of Anglesey, in 1831. Murray was
knight A knight is a person granted an honorary title of knighthood by a head of state (including the Pope) or representative for service to the monarch, the church or the country, especially in a military capacity. Knighthood finds origins in the Gr ...
ed in 1833 by his employer, and received an honorary degree in Medicine from Dublin University the following year. He was appointed as an inspector of anatomical schools in Ireland, and was a member of the central board of health.


Scandal

He travelled to Rome Italy in 1844, where he undertook some studies into the causes of
malaria Malaria is a mosquito-borne infectious disease that affects humans and other animals. Malaria causes symptoms that typically include fever, tiredness, vomiting, and headaches. In severe cases, it can cause jaundice, seizures, coma, or death. S ...
. His research led to his view that the fever was caused by electro-galvanic currents and accumulations. He felt passionate towards his appointment as the resident physician to Anglesey, and subsequently to Anglesey's successors,
George Phipps, 2nd Marquess of Normanby George Augustus Constantine Phipps, 2nd Marquess of Normanby (23 July 1819 – 3 April 1890), styled Viscount Normanby between 1831 and 1838 and Earl of Mulgrave between 1838 and 1863, was a British Liberal politician and colonial governor of Nov ...
in 1835, and
Viscount Ebrington A viscount ( , for male) or viscountess (, for female) is a title used in certain European countries for a noble of varying status. In many countries a viscount, and its historical equivalents, was a non-hereditary, administrative or judicial ...
in 1839. However, Murray's son, John, brought shame on his father by publishing a novel, entitled ''The Viceroy'', which satirised "the worms and sycophants of Irish lord lieutenancy". The historian Richard Davenport-Hines, writing for the Dictionary of National Biography, noticed how the situation could have caused Murray much embarrassment and was probably the reason why, in 1841, the newly appointed
Earl de Grey Earl de Grey, of Wrest in the County of Bedford, was a title in the Peerage of the United Kingdom. History The title was created on 25 October 1816 (as Countess de Grey) for Amabell Hume-Campbell, Dowager Lady Polwarth and ''suo jure'' 5th ...
,
George Robinson, 1st Marquess of Ripon George Frederick Samuel Robinson, 1st Marquess of Ripon, (24 October 1827 – 9 July 1909), styled Viscount Goderich from 1833 to 1859 and known as the Earl of Ripon in 1859 and as the Earl de Grey and Ripon from 1859 to 1871, was a British p ...
, dispensed with Murray's services.


Studies in heat and electricity

Murray was the resident physician to the Netterville Dispensary and to the Anglesey Lying-In Hospital, Dublin."Notices to Correspondence
''The Edinburgh Medical and Surgical Journal: Exhibiting a Concise'', Volume 46, p. 3.
He was the first physician to recommend the breathing in of iodine in water vapour for respiratory diseases, and in 1829, he published his Dissertation on the influence of heat and humidity, with practical observations on the inhalation of iodine. This was reissued in 1837, with additions to his technique of
tracheotomy Tracheotomy (, ), or tracheostomy, is a surgical airway management procedure which consists of making an incision (cut) on the anterior aspect (front) of the neck and opening a direct airway through an incision in the trachea (windpipe). The r ...
operations. His report analysed body temperatures in various diseases, and looked at the effects of heat and fluidity on medicines. It further suggested that dilution aided the effects of most medicines. However, it was the area of
electrotherapy Electrotherapy is the use of electrical energy as a medical treatment. In medicine, the term ''electrotherapy'' can apply to a variety of treatments, including the use of electrical devices such as deep brain stimulators for neurological dise ...
that Murray was most interested in; he (wrongly) attributed electricity to be the cause of cholera and other epidemics. He further opined that epidemics were a result of disturbances of natural electricity; either depletion or excess of electricity in the nervous system could derange the vital organs. During the cholera epidemic of 1832, he lowered the atmospheric pressure on the external surface of sufferers' bodies using an air pump based on his own design. He also endorsed the medical use of atmospheric pressure in air baths. He reported his findings in various medical journals and publications.


Personal life

In 1809 Murray married Mary née Sharrock, with whom he had several children. When she died, he married again, this time to Mary née Allen in 1848; they had one daughter. Murray is the great-grandfather of the actor
Michael Hordern Sir Michael Murray Hordern Commander of the Order of the British Empire, CBE (3 October 19112 May 1995)Morley, Sheridan"Hordern, Michael Murray (1911–1995)" ''Oxford Dictionary of National Biography'', Oxford University Press, 2004, online e ...
.Hordern, pp. 1–2. Murray died at his home in Dublin on 8 December 1871 and was later buried at
Glasnevin Cemetery Glasnevin Cemetery ( ga, Reilig Ghlas Naíon) is a large cemetery in Glasnevin, Dublin, Ireland which opened in 1832. It holds the graves and memorials of several notable figures, and has a museum. Location The cemetery is located in Glasne ...
, Dublin.


Notes and references

Notes References


Sources

* * * {{DEFAULTSORT:Murray, James 19th-century Irish medical doctors 1788 births 1871 deaths Medical doctors from Derry (city) Alumni of the University of Edinburgh Alumni of the University of Edinburgh Medical School Irish healthcare managers 19th-century Irish businesspeople Businesspeople from Derry (city)