JWH-196
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JWH-196 is a synthetic
cannabinoid receptor Cannabinoid receptors, located throughout the body, are part of the endocannabinoid system a class of cell membrane receptors in the G protein-coupled receptor superfamily. As is typical of G protein-coupled receptors, the cannabinoid recepto ...
ligand from the naphthylmethylindole family. It is the
indole Indole is an aromatic heterocyclic organic compound with the formula C8 H7 N. It has a bicyclic structure, consisting of a six-membered benzene ring fused to a five-membered pyrrole ring. Indole is widely distributed in the natural environmen ...
2-methyl derivative of related compound JWH-175, and the carbonyl reduced analog of
JWH-007 JWH-007 is an analgesic chemical from the naphthoylindole family, which acts as a cannabinoid agonist at both the CB1 and CB2 receptors. It was first reported in 1994 by a group including the noted cannabinoid chemist John W. Huffman. It was th ...
. The binding affinity of JWH-196 for the CB1 receptor is reported as Ki = 151 ± 18 nM. In the United States, all CB1 receptor agonists of the 3-(1-naphthylmethane)indole class such as JWH-196 are
Schedule I Controlled Substance This is the list of Schedule I drugs as defined by the United States Controlled Substances Act. 21 CFRbr>1308.11(CSA Sched I) with changes through (Oct 18, 2012). Retrieved September 6, 2013. The following findings are required for drugs to be pl ...
s.


See also

*
JWH-007 JWH-007 is an analgesic chemical from the naphthoylindole family, which acts as a cannabinoid agonist at both the CB1 and CB2 receptors. It was first reported in 1994 by a group including the noted cannabinoid chemist John W. Huffman. It was th ...
* JWH-175


References

JWH cannabinoids CB1 receptor agonists 1-Naphthyl compounds Indoles {{cannabinoid-stub