JTE-907 is a drug used in scientific research that acts as a selective
CB2 inverse agonist
In pharmacology, an inverse agonist is a drug that binds to the same receptor as an agonist but induces a pharmacological response opposite to that of the agonist.
A neutral antagonist has no activity in the absence of an agonist or inverse ago ...
. It has
antiinflammatory
Anti-inflammatory is the property of a substance or treatment that reduces inflammation or swelling. Anti-inflammatory drugs, also called anti-inflammatories, make up about half of analgesics. These drugs remedy pain by reducing inflammation as ...
effects in animal studies, thought to be mediated by an interaction between the CB
2 receptor and
IgE.
See also
*
JTE 7-31
JTE 7-31 is a selective cannabinoid receptor agonist invented by Japan Tobacco. It is a reasonably highly selective CB2 agonist, but still retains appreciable affinity at CB1, with a Ki of 0.088nM at CB2 vs 11nM at CB1.
Legality
JTE 7-31 is il ...
References
{{cannabinoid-stub
Cannabinoids
Benzodioxoles
2-Quinolone ethers at the benzene ring
Carboxamides
Japan Tobacco