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The International System for Human Cytogenomic Nomenclature (previously International System for Human Cytogenetic Nomenclature), ISCN in short, is an international standard for human chromosome 
Abbreviations of this system include a minus sign (-) for chromosome deletions, and ''del'' for deletions of parts of a chromosome.
"Standardization in Human Cytogenetics." (PDF)
''Birth Defects: Original Article Series'', Vol 8, No 7 (The National Foundation, New York 1972) * Chicago Conference (1966): "Standardization in Human Cytogenetics." ''Birth Defects: Original Article Series'', Vol 2, No 2 (The National Foundation, New York 1966). * London Conference (1963)
"London Conference on the Normal Human Karyotype."
''Cytogenetics'' 2:264–268 (1963) * Denver Conference (1960)
"A proposed standard system of nomenclature of human mitotic chromosomes."
''The Lancet'' 275.7133 (1960): 1063-1065.
About the ISCN recommendations
- Human Genome Variation Society {{Chromosome genetics Cytogenetics Biological nomenclature
nomenclature
Nomenclature (, ) is a system of names or terms, or the rules for forming these terms in a particular field of arts or sciences. The principles of naming vary from the relatively informal conventions of everyday speech to the internationally ag ...
, which includes band names, symbols and abbreviated terms used in the description of human chromosome and chromosome abnormalities.
The ISCN has been used as the central reference among cytogeneticist
Cytogenetics is essentially a branch of genetics, but is also a part of cell biology/cytology (a subdivision of human anatomy), that is concerned with how the chromosomes relate to cell behaviour, particularly to their behaviour during mitosis a ...
s since 1960.Slovak M.L., Theisen A., Shaffer L.G. (2013) "Human Chromosome Nomenclature: An Overview and Definition of Terms." In: Gersen S., Keagle M. (eds) ''The Principles of Clinical Cytogenetics.'' Springer, New York, NY
Abbreviations of this system include a minus sign (-) for chromosome deletions, and ''del'' for deletions of parts of a chromosome.
Revision history
* ISCN (2020). S. Karger Publishing. * ISCN (2016). S. Karger Publishing. * ISCN (2013). S. Karger Publishing. * ISCN (2009). S. Karger Publishing. * ISCN (2005). S. Karger Publishing. * ISCN (1995). S. Karger Publishing. * ISCN (1991). S. Karger Publishing. * ISCN (1985). S. Karger Publishing. * ISCN (1981). S. Karger Publishing. * ISCN (1978). S. Karger Publishing. * Paris Conference (1971)"Standardization in Human Cytogenetics." (PDF)
''Birth Defects: Original Article Series'', Vol 8, No 7 (The National Foundation, New York 1972) * Chicago Conference (1966): "Standardization in Human Cytogenetics." ''Birth Defects: Original Article Series'', Vol 2, No 2 (The National Foundation, New York 1966). * London Conference (1963)
"London Conference on the Normal Human Karyotype."
''Cytogenetics'' 2:264–268 (1963) * Denver Conference (1960)
"A proposed standard system of nomenclature of human mitotic chromosomes."
''The Lancet'' 275.7133 (1960): 1063-1065.
See also
*Locus (genetics)
In genetics, a locus (plural loci) is a specific, fixed position on a chromosome where a particular gene or genetic marker is located. Each chromosome carries many genes, with each gene occupying a different position or locus; in humans, the tota ...
* Cytogenetic notation
The following table summarizes symbols and abbreviations used in cytogenetics:
See also
*Chromosome abnormalities
*Directionality (molecular biology) for 3' and 5' notation
*locus (genetics)
In genetics, a locus (plural loci) is a specific, fi ...
References
External links
About the ISCN recommendations
- Human Genome Variation Society {{Chromosome genetics Cytogenetics Biological nomenclature