In vivo fertilization
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Insemination is the introduction of sperm into a female’s
reproductive system The reproductive system of an organism, also known as the genital system, is the biological system made up of all the anatomical organs involved in sexual reproduction. Many non-living substances such as fluids, hormones, and pheromones are als ...
for the purpose of impregnating, also called fertilizing, the female for
sexual reproduction Sexual reproduction is a type of reproduction that involves a complex life cycle in which a gamete ( haploid reproductive cells, such as a sperm or egg cell) with a single set of chromosomes combines with another gamete to produce a zygote th ...
. The sperm is introduced into the
uterus The uterus (from Latin ''uterus'', plural ''uteri'') or womb () is the organ in the reproductive system of most female mammals, including humans that accommodates the embryonic and fetal development of one or more embryos until birth. The ...
of a mammal or the
oviduct The oviduct in mammals, is the passageway from an ovary. In human females this is more usually known as the Fallopian tube or uterine tube. The eggs travel along the oviduct. These eggs will either be fertilized by spermatozoa to become a zygote, o ...
of an oviparous (egg-laying) animal. In mammals, insemination normally occurs during sexual intercourse or
copulation Sexual intercourse (or coitus or copulation) is a sexual activity typically involving the insertion and thrusting of the penis into the vagina for sexual pleasure or reproduction.Sexual intercourse most commonly means penile–vaginal penetra ...
, but insemination can take place in other ways, such as by
artificial insemination Artificial insemination is the deliberate introduction of sperm into a female's cervix or uterine cavity for the purpose of achieving a pregnancy through in vivo fertilization by means other than sexual intercourse. It is a fertility treatment ...
. In humans, the act and form of insemination has legal, moral and interpersonal implications. However, whether insemination takes place naturally or by artificial means, the pregnancy and the progress of it will be the same. Insemination may be called ''in vivo'' fertilisation (from ''
in vivo Studies that are ''in vivo'' (Latin for "within the living"; often not italicized in English) are those in which the effects of various biological entities are tested on whole, living organisms or cells, usually animals, including humans, and ...
'' meaning "within the living") because an egg is fertilized inside the body, this is in contrast with
in vitro fertilisation In vitro fertilisation (IVF) is a process of fertilisation where an egg is combined with sperm in vitro ("in glass"). The process involves monitoring and stimulating an individual's ovulatory process, removing an ovum or ova (egg or eggs) ...
(IVF). In plants, the fertilization process is referred to as
pollination Pollination is the transfer of pollen from an anther of a plant to the stigma of a plant, later enabling fertilisation and the production of seeds, most often by an animal or by wind. Pollinating agents can be animals such as insects, birds, a ...
. It is the process of transfer of pollen grains from one anther to stigma of other plants.


Natural insemination

Insemination of a woman by sexual intercourse is referred to as "natural insemination" (NI) (i.e., insemination by natural means). Natural insemination involves
ejaculation Ejaculation is the discharge of semen (the ''ejaculate''; normally containing sperm) from the male reproductory tract as a result of an orgasm. It is the final stage and natural objective of male sexual stimulation, and an essential compone ...
during penile–vaginal penetration, with the erect penis inside the
vagina In mammals, the vagina is the elastic, muscular part of the female genital tract. In humans, it extends from the vestibule to the cervix. The outer vaginal opening is normally partly covered by a thin layer of mucosal tissue called the hymen ...
. If an artificial lubricant needs to be used, care must be taken that it does not have spermicidal properties. During ejaculation,
semen Semen, also known as seminal fluid, is an organic bodily fluid created to contain spermatozoa. It is secreted by the gonads (sexual glands) and other sexual organs of male or hermaphroditic animals and can fertilize the female ovum. Sem ...
, containing male gametes known as sperm, is expelled through the penis into the moist and warm environment of person’s
reproductive tract The reproductive system of an organism, also known as the genital system, is the biological system made up of all the anatomical organs involved in sexual reproduction. Many non-living substances such as fluids, hormones, and pheromones are al ...
. In humans, semen is usually ejaculated into the posterior
vaginal fornix The fornices of the vagina (sing. fornix of the vagina or fornix vaginae) are the superior portions of the vagina, extending into the recesses created by the vaginal portion of cervix. The word "fornix" is Latin for "arch". Structure There are t ...
in direct contact with cervical mucus, though sperm may swim from other areas of the vagina or vulva to the cervix. The average volume of semen produced at ejaculation is 2 to 5ml (about 1 teaspoon), containing an average of 182 million sperm. Only a small proportion of the sperm in each ejaculation reach the site of fertilization in the fallopian tubes, their numbers decreasing exponentially as they progress through the
female reproductive tract The female reproductive system is made up of the internal and external sex organs that function in the reproduction of new offspring. In humans, the female reproductive system is immature at birth and develops to maturity at puberty to be abl ...
. The majority of sperm either die in the acidic environment of the vagina or drip out with the semen. Prior to
ovulation Ovulation is the release of eggs from the ovaries. In women, this event occurs when the ovarian follicles rupture and release the secondary oocyte ovarian cells. After ovulation, during the luteal phase, the egg will be available to be fertilize ...
, the cervical mucus becomes thinner and more hospitable to sperm. Sperm swim rapidly into the uterus upon encountering cervical mucus, though many become lost in the cervical crypts where they either die or are delayed. Further attrition occurs in the uterus, where sperm are attacked by the female immune system. Only about 100-1000 sperm reach the fallopian tubes, where they may survive for up to 6 days. If ovulation occurs and the sperm encounter an ovum in the fallopian tube, fertilization may occur. A woman may also be naturally inseminated while having penile-vaginal intercourse for pleasure without any intent to conceive. This may be unintentional as a result of the failure of a
barrier A barrier or barricade is a physical structure which blocks or impedes something. Barrier may also refer to: Places * Barrier, Kentucky, a community in the United States * Barrier, Voerendaal, a place in the municipality of Voerendaal, Netherl ...
or
behavioural Behavior (American English) or behaviour (British English) is the range of actions and mannerisms made by individuals, organisms, systems or artificial entities in some environment. These systems can include other systems or organisms as wel ...
method of
contraception Birth control, also known as contraception, anticonception, and fertility control, is the use of methods or devices to prevent unwanted pregnancy. Birth control has been used since ancient times, but effective and safe methods of birth contr ...
, or may be intentional if relying on female contraceptive methods or indifferent to the possibility of pregnancy. In most cultures, insemination by a male through sexual intercourse, whether the woman's husband, normal sex partner or not, is subject to social and sexual inhibitions and taboos, and has legal, moral and interpersonal implications. The term is also used in the context of third-party insemination, where a male who is not the woman's usual sexual partner (i.e., a sperm donor) fathers a child for the woman by providing his sperm through sexual intercourse rather than by providing his sperm for it to be used to produce a pregnancy in the woman by artificial means. The incidence of natural insemination by a sperm donor is usually a private matter, and may also carry greater health risks than where sperm has been processed by a fertility center. Advocates claim natural insemination generates higher pregnancy rates and a more 'natural' conception which does not involve the intervention and intrusion of third parties. However, it has not been medically proven that natural insemination has an increased chance of pregnancy. Additionally, conceiving through natural insemination is considered a natural process, so the father may be liable for child support and have custody and other rights of the child. The law usually draws a distinction between a man fathering a child by natural means, and a man who provides his sperm for it to be used to father a child by artificial means (i.e. by artificial insemination).


Artificial insemination

Artificial insemination Artificial insemination is the introduction of sperm into the reproductive tract of a female by means other than sexual intercourse for the purpose of impregnating or fertilizing the female. In humans, artificial insemination may be used when a woman or her normal sex partner cannot, for any of a number of reasons, conceive by natural means. A number of artificial insemination strategies are available, including
intracervical insemination Artificial insemination is the deliberate introduction of sperm into a female's cervix or uterine cavity for the purpose of achieving a pregnancy through in vivo fertilization by means other than sexual intercourse. It is a fertility treatm ...
(ICI) and
intrauterine insemination Artificial insemination is the deliberate introduction of sperm into a female's cervix or uterine cavity for the purpose of achieving a pregnancy through in vivo fertilization by means other than sexual intercourse. It is a fertility treatm ...
(IUI). Compared with natural insemination, artificial insemination may be more invasive, and may require professional assistance and medical expertise, which will have a higher cost. ICI attempts to simulate natural insemination, without the sexual element. It is painless and is the simplest, easiest and most common method of artificial insemination, and can be performed in the home, either by the female on herself or with non-professional assistance. ICI involves the introduction of unwashed or raw semen into the vagina at the entrance to the cervix, usually by means of a needleless syringe. The sperm for insemination may be provided by either a sexual partner of the female’s choice or by a
sperm donor Sperm donation is the provision by a man of his sperm with the intention that it be used in the artificial insemination or other 'fertility treatment' of a woman or women who are not his sexual partners in order that they may become pregnant by h ...
. Donor sperm is most commonly used by lesbian couples, single women, and heterosexual couples when the male partner is suffering from male infertility. There have been situations where a female has been inseminated with sperm collected from a female’s partner before him going off to war or even harvested after he has already died. There are laws in some countries which restrict and regulate who can donate sperm and who is able to receive artificial insemination, and the consequences of such insemination. Subject to any regulations restricting who can obtain donor sperm, donor sperm is available to all women who, for whatever reason, want or need it. Some women living in a jurisdiction which does not permit artificial insemination in the circumstance in which she finds herself may travel to another jurisdiction (a 'fertility destination') which permits it. (See
Sperm donation laws by country Sperm donation laws vary by country. Most countries have laws to cover sperm donations which, for example, place limits on how many children a sperm donor may give rise to, or which limit or prohibit the use of donor semen after the donor has died, ...
.) Artificial insemination has been and continues to be commonly used in
livestock breeding Animal husbandry is the branch of agriculture concerned with animals that are raised for meat, fibre, milk, or other products. It includes day-to-day care, selective breeding, and the raising of livestock. Husbandry has a long history, start ...
as an efficient way of increasing production.


Other forms of insemination

In various other animal species, sperm can be introduced into the female's reproductive tract by various means. For example, in some species of hemiptera sperm can be introduced violently by
traumatic insemination Traumatic insemination, also known as hypodermic insemination, is the mating practice in some species of invertebrates in which the male pierces the female's abdomen with his aedeagus and injects his sperm through the wound into her abdominal cav ...
,
parenteral A route of administration in pharmacology and toxicology is the way by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. ...
injection through the body wall. In some species of animals, sperm finds its way through the body wall when the
spermatophore A spermatophore or sperm ampulla is a capsule or mass containing spermatozoa created by males of various animal species, especially salamanders and arthropods, and transferred in entirety to the female's ovipore during reproduction. Spermatophores ...
is left in contact with the female's skin, such as in the
onychophora Onychophora (from grc, ονυχής, , "claws"; and , , "to carry"), commonly known as velvet worms (due to their velvety texture and somewhat wormlike appearance) or more ambiguously as peripatus (after the first described genus, '' Peripatus ...
(velvet worms).


See also

* Assisted reproductive technology * Conception device * Fertilisation * Fertility fraud *
Internal fertilization Internal fertilization is the union of an egg and sperm cell during sexual reproduction inside the female body. Internal fertilization, unlike its counterpart, external fertilization, brings more control to the female with reproduction. For inte ...
* Sperm bank *
Sperm donation Sperm donation is the provision by a man of his sperm with the intention that it be used in the artificial insemination or other 'fertility treatment' of a woman or women who are not his sexual partners in order that they may become pregnant by h ...
*
Sperm theft Sperm theft, also known as unauthorized use of sperm, forced fatherhood, spermjacking or (a portmanteau of sperm and burgling), occurs when a man's semen is used, against his will or without his knowledge or consent, to inseminate a woman. It ...
*
Traumatic insemination Traumatic insemination, also known as hypodermic insemination, is the mating practice in some species of invertebrates in which the male pierces the female's abdomen with his aedeagus and injects his sperm through the wound into her abdominal cav ...


References


External links

* Photos of
Honeybee's insemination
{{Authority control Animal sexuality Reproduction in mammals Semen