History of neurology and neurosurgery
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The study of
neurology Neurology (from el, νεῦρον (neûron), "string, nerve" and the suffix -logia, "study of") is the branch of medicine dealing with the diagnosis and treatment of all categories of conditions and disease involving the brain, the spinal ...
and
neurosurgery Neurosurgery or neurological surgery, known in common parlance as brain surgery, is the medical specialty concerned with the surgical treatment of disorders which affect any portion of the nervous system including the brain, spinal cord and pe ...
dates back to prehistoric times, but the academic disciplines did not begin until the 16th century. From an observational science they developed a systematic way of approaching the nervous system and possible interventions in neurological disease.


Early history


Ancient

Trepanation, similar to some techniques used today, is the oldest surgical procedure known and was practised in the Stone Age in many parts of the world, and in some areas may have been quite widespread. The main pieces of archaeological evidence are in the forms of cave paintings and human remains. One third of 120 skulls found at a site in
France France (), officially the French Republic ( ), is a country primarily located in Western Europe. It also comprises of overseas regions and territories in the Americas and the Atlantic, Pacific and Indian Oceans. Its metropolitan area ...
dating to 6500 BCE had undergone trepanning. It was also practised widely in the pre-Columbian Andes. These procedures were mostly performed on combatants, with evidence from skeletal remains revealing that the earliest methods usually resulted in death. However, by the 1400s, Incas proved to be "skilled surgeons", as survival rates rose to about 90%, infection rates following the procedure were low and evidence was found showing that some individuals survived the surgery on multiple occasions. Incan surgeons learned to avoid areas of the head that would cause injury, using a scraping method on the skull that would cause less trauma. They also likely used medicinal herbs of the time, such as
coca Coca is any of the four cultivated plants in the family Erythroxylaceae, native to western South America. Coca is known worldwide for its psychoactive alkaloid, cocaine. The plant is grown as a cash crop in the Argentine Northwest, Bolivia, ...
and alcohol for pain while
balsam Balsam is the resinous exudate (or sap) which forms on certain kinds of trees and shrubs. Balsam (from Latin balsamum "gum of the balsam tree", ultimately from Semitic, Aramaic ''busma'', Arabic ''balsam'' and Hebrew ''basam'', "spice", "perfume ...
and saponin would be employed for antibiotic purposes. An ancient Egyptian treatise concerning
trauma Trauma most often refers to: * Major trauma, in physical medicine, severe physical injury caused by an external source * Psychological trauma, a type of damage to the psyche that occurs as a result of a severely distressing event *Traumatic i ...
surgery, the Edwin Smith papyrus, contains descriptions and suggests treatments for various injuries, including some of neurological nature. Specifically, there are descriptions of the meninges, the external surface of the brain, the
cerebrospinal fluid Cerebrospinal fluid (CSF) is a clear, colorless body fluid found within the tissue that surrounds the brain and spinal cord of all vertebrates. CSF is produced by specialised ependymal cells in the choroid plexus of the ventricles of the ...
and the intracranial pulsations.Wilkins, 1964 Not only are these neurological features mentioned, but it is also noticed that some bodily functions can be impaired by brain injuries or injuries to the cervical spine. There are many other examples of observations of neurological phenomena throughout history. The Sumerians illustrated paraplegia caused by physical trauma in a bas relief of a lion with an arrow in its back. Neurological disorders not caused by physical disorder were also investigated.
Buddha Siddhartha Gautama, most commonly referred to as the Buddha, was a wandering ascetic and religious teacher who lived in South Asia during the 6th or 5th century BCE and founded Buddhism. According to Buddhist tradition, he was born in L ...
's physician, Jīvaka Komārabhacca, performed surgery to remove two parasites from a patient's brain in the 5th century BCE. Slightly later, the
ancient Greek Ancient Greek includes the forms of the Greek language used in ancient Greece and the ancient world from around 1500 BC to 300 BC. It is often roughly divided into the following periods: Mycenaean Greek (), Dark Ages (), the Archaic p ...
physician
Hippocrates Hippocrates of Kos (; grc-gre, Ἱπποκράτης ὁ Κῷος, Hippokrátēs ho Kôios; ), also known as Hippocrates II, was a Greek physician of the classical period who is considered one of the most outstanding figures in the history o ...
was convinced that
epilepsy Epilepsy is a group of non-communicable neurological disorders characterized by recurrent epileptic seizures. Epileptic seizures can vary from brief and nearly undetectable periods to long periods of vigorous shaking due to abnormal electrica ...
has a natural cause, not a sacred one.World Health Organization, Fact Sheet #168 The ancient Greeks also dissected the nervous system. For example,
Aristotle Aristotle (; grc-gre, Ἀριστοτέλης ''Aristotélēs'', ; 384–322 BC) was a Greek philosopher and polymath during the Classical period in Ancient Greece. Taught by Plato, he was the founder of the Peripatetic school of ph ...
(although he misunderstood the function of the brain) describes the meninges and also distinguishes between the
cerebrum The cerebrum, telencephalon or endbrain is the largest part of the brain containing the cerebral cortex (of the two cerebral hemispheres), as well as several subcortical structures, including the hippocampus, basal ganglia, and olfactory bulb ...
and the cerebellum. Slightly later, in Rome,
Galen Aelius Galenus or Claudius Galenus ( el, Κλαύδιος Γαληνός; September 129 – c. AD 216), often Anglicized as Galen () or Galen of Pergamon, was a Greek physician, surgeon and philosopher in the Roman Empire. Considered to be one ...
performed many dissections of the
nervous system In biology, the nervous system is the highly complex part of an animal that coordinates its actions and sensory information by transmitting signals to and from different parts of its body. The nervous system detects environmental changes ...
in a variety of species, including the ape. One particular discovery he made was of the importance of the
recurrent laryngeal nerve The recurrent laryngeal nerve (RLN) is a branch of the vagus nerve ( cranial nerve X) that supplies all the intrinsic muscles of the larynx, with the exception of the cricothyroid muscles. There are two recurrent laryngeal nerves, right and ...
s. Originally, he cut through them accidentally while performing an experiment on the nerves that control breathing by
vivisection Vivisection () is surgery conducted for experimental purposes on a living organism, typically animals with a central nervous system, to view living internal structure. The word is, more broadly, used as a pejorative catch-all term for Animal testi ...
of a strapped-down, squealing pig. The pig immediately stopped squealing, but continued struggling. Galen then performed the same experiment on a variety of animals, including dogs, goats, bears, lions, cows and monkeys, finding similar results each time. Finally, to publicise this new result, Galen demonstrated the experiment on a pair of pigs to a large audience in Rome, telling them: "there is a hairlike pair f nervesin the muscles of the larynx on both left and right, which if ligated or cut render the animal speechless without damaging either its life or functional activity". With surgery,
Hua Tuo Hua Tuo ( 140–208), courtesy name Yuanhua, was a Chinese physician who lived during the late Eastern Han dynasty. The historical texts ''Records of the Three Kingdoms'' and ''Book of the Later Han'' record Hua Tuo as the first person in China ...
was an ancient Chinese physician and surgical pioneer who is said to have performed neurosurgical procedures. In
Al-Andalus Al-Andalus translit. ; an, al-Andalus; ast, al-Ándalus; eu, al-Andalus; ber, ⴰⵏⴷⴰⵍⵓⵙ, label= Berber, translit=Andalus; ca, al-Àndalus; gl, al-Andalus; oc, Al Andalús; pt, al-Ândalus; es, al-Ándalus () was the M ...
from 936 to 1013 AD,
Al-Zahrawi Abū al-Qāsim Khalaf ibn al-'Abbās al-Zahrāwī al-Ansari ( ar, أبو القاسم خلف بن العباس الزهراوي;‎ 936–1013), popularly known as al-Zahrawi (), Latinised as Albucasis (from Arabic ''Abū al-Qāsim''), was ...
evaluated patients and performed surgical treatments of head injuries, skull fractures, spinal injuries, hydrocephalus, subdural effusions and headache. Concurrently in Persia, Avicenna also presented detailed knowledge about skull fractures and their surgical treatments.


Anatomy and physiology

* Along with most other sciences, the first real advances in neurology and neurosurgery after the Greeks occur in the
Renaissance The Renaissance ( , ) , from , with the same meanings. is a period in European history The history of Europe is traditionally divided into four time periods: prehistoric Europe (prior to about 800 BC), classical antiquity (800 BC to AD ...
. The invention of the printing press allowed the publication of anatomical textbooks, pages, allowing the dissemination of knowledge. An early example is
Johann Peyligk Johann, typically a male given name, is the German form of ''Iohannes'', which is the Latin form of the Greek name ''Iōánnēs'' (), itself derived from Hebrew name ''Yochanan'' () in turn from its extended form (), meaning "Yahweh is Gracious" ...
's ''Compendium philosophiae naturalis'', published in
Leipzig Leipzig ( , ; Upper Saxon: ) is the most populous city in the German state of Saxony. Leipzig's population of 605,407 inhabitants (1.1 million in the larger urban zone) as of 2021 places the city as Germany's eighth most populous, as ...
, Germany in 1499. This work contained 11 woodcuts, depicting the
dura mater In neuroanatomy, dura mater is a thick membrane made of dense irregular connective tissue that surrounds the brain and spinal cord. It is the outermost of the three layers of membrane called the meninges that protect the central nervous system. ...
and
pia mater Pia mater ( or ),Entry "pia mater"
in
ventricles.Tessman & Suarez, 2002 * A revolution took place in both neurology in particular and in anatomy in general when
Andreas Vesalius Andreas Vesalius (Latinized from Andries van Wezel) () was a 16th-century anatomist, physician, and author of one of the most influential books on human anatomy, ''De Humani Corporis Fabrica Libri Septem'' (''On the fabric of the human body'' ' ...
published his ''
De humani corporis fabrica ''De Humani Corporis Fabrica Libri Septem'' (Latin, lit. "On the fabric of the human body in seven books") is a set of books on human anatomy written by Andreas Vesalius (1514–1564) and published in 1543. It was a major advance in the history ...
'' in 1543. It includes detailed images depicting the ventricles,
cranial nerves Cranial nerves are the nerves that emerge directly from the brain (including the brainstem), of which there are conventionally considered twelve pairs. Cranial nerves relay information between the brain and parts of the body, primarily to and f ...
,
pituitary gland In vertebrate anatomy, the pituitary gland, or hypophysis, is an endocrine gland, about the size of a chickpea and weighing, on average, in humans. It is a protrusion off the bottom of the hypothalamus at the base of the brain. The ...
, meninges, structures of the eye, the vascular supply to the brain and spinal cord, and an image of the peripheral nerves. Vesalius, unlike many of his contemporaries, did not subscribe to the then common belief that the ventricles were responsible for brain function, arguing that many animals have similar systems of ventricles to those of humans, but had no true intelligence. It appears that he rarely removed the brain from the
skull The skull is a bone protective cavity for the brain. The skull is composed of four types of bone i.e., cranial bones, facial bones, ear ossicles and hyoid bone. However two parts are more prominent: the cranium and the mandible. In humans, th ...
before cutting it, most of his diagrams showing the brain sitting inside a severed head. In 1549, Jason Pratensis published an important neurology book "De Cerebri Morbis". This book was devoted to neurological diseases, and discussed symptoms, as well as ideas from Galen and other Greek, Roman and Arabic authors.
Thomas Willis Thomas Willis FRS (27 January 1621 – 11 November 1675) was an English doctor who played an important part in the history of anatomy, neurology and psychiatry, and was a founding member of the Royal Society. Life Willis was born on his pare ...
in 1664, published his Anatomy of the Brain, followed by Cerebral Pathology in 1667. He removed the brain from the cranium, and was able to describe it more clearly, setting forth the
circle of Willis The circle of Willis (also called Willis' circle, loop of Willis, cerebral arterial circle, and Willis polygon) is a circulatory anastomosis that supplies blood to the brain and surrounding structures in reptiles, birds and mammals, including huma ...
– the circle of vessels that enables arterial supply of the brain. He had some notions as to brain function, including a vague idea as to localization and reflexes, and described epilepsy,
apoplexy Apoplexy () is rupture of an internal organ and the accompanying symptoms. The term formerly referred to what is now called a stroke. Nowadays, health care professionals do not use the term, but instead specify the anatomic location of the bleedi ...
and paralysis. He was among the first few authors to use the word "neurology," after anatomist Jean Riolan the Younger in 1610. A beginning of the understanding of disease came with the first morbid anatomists, morbid anatomical illustration, and the development of effective colour printing.
Matthew Baillie Matthew Baillie FRS (27 October 1761 – 23 September 1823) was a British physician and pathologist, credited with first identifying transposition of the great vessels (TGV) and situs inversus. Early life and education He was born in the mans ...
(1761–1823) and Jean Cruveilhier (1791–1874) illustrated the lesions in stroke, in 1799 and 1829 respectively.


Bioelectricity and Microscopy

The famous philosopher
René Descartes René Descartes ( or ; ; Latinized: Renatus Cartesius; 31 March 1596 – 11 February 1650) was a French philosopher, scientist, and mathematician, widely considered a seminal figure in the emergence of modern philosophy and science. Ma ...
(1596–1650) speculated that every activity of an animal was a necessary reaction to some external stimulus; the connection between the stimulus and the response was made through a definite nervous path. Luigi Galvani (1737–1798) demonstrated that electrical stimulation of nerve produced muscle contraction, and the competing work of Charles Bell (1774–1842) and
François Magendie __NOTOC__ François Magendie (6 October 1783 – 7 October 1855) was a French physiologist, considered a pioneer of experimental physiology. He is known for describing the foramen of Magendie. There is also a ''Magendie sign'', a downward ...
(1783–1855 ) led to the view that the ventral horns of the
spinal cord The spinal cord is a long, thin, tubular structure made up of nervous tissue, which extends from the medulla oblongata in the brainstem to the lumbar region of the vertebral column (backbone). The backbone encloses the central canal of the sp ...
were
motor An engine or motor is a machine designed to convert one or more forms of energy into mechanical energy. Available energy sources include potential energy (e.g. energy of the Earth's gravitational field as exploited in hydroelectric power g ...
and the dorsal horns sensory. Only when cells were identified microscopically was it possible to progress beyond the crudest anatomical notion. J.E. Purkinje (1787–1869) in 1837 gave the first description of
neuron A neuron, neurone, or nerve cell is an electrically excitable cell that communicates with other cells via specialized connections called synapses. The neuron is the main component of nervous tissue in all animals except sponges and placozoa. ...
es, indeed a very early description of
cell Cell most often refers to: * Cell (biology), the functional basic unit of life Cell may also refer to: Locations * Monastic cell, a small room, hut, or cave in which a religious recluse lives, alternatively the small precursor of a monastery ...
s of any kind. Later Golgi and Cajal stained the ramifying branches of nerve cells; these could only touch, or synapse. The brain now had demonstrated form, without localised function. A
hemiplegic Hemiparesis, or unilateral paresis, is weakness of one entire side of the body ('' hemi-'' means "half"). Hemiplegia is, in its most severe form, complete paralysis of half of the body. Hemiparesis and hemiplegia can be caused by different medic ...
patient who could not speak led
Paul Broca Pierre Paul Broca (, also , , ; 28 June 1824 – 9 July 1880) was a French physician, anatomist and anthropologist. He is best known for his research on Broca's area, a region of the frontal lobe that is named after him. Broca's area is involve ...
(1824–1880) to the view that functions in the
cerebral cortex The cerebral cortex, also known as the cerebral mantle, is the outer layer of neural tissue of the cerebrum of the brain in humans and other mammals. The cerebral cortex mostly consists of the six-layered neocortex, with just 10% consistin ...
were anatomically localised.
Ivan Pavlov Ivan Petrovich Pavlov ( rus, Ива́н Петро́вич Па́влов, , p=ɪˈvan pʲɪˈtrovʲɪtɕ ˈpavləf, a=Ru-Ivan_Petrovich_Pavlov.ogg; 27 February 1936), was a Russian and Soviet experimental neurologist, psychologist and physio ...
(1849–1936) realised as his dogs dribbled that a simple reflex could be modified by higher brain functions. These neurological ideas were coordinated and integrated by the neurophysiologist
Charles Scott Sherrington Sir Charles Scott Sherrington (27 November 1857 – 4 March 1952) was an eminent English neurophysiologist. His experimental research established many aspects of contemporary neuroscience, including the concept of the spinal reflex as a system ...
(1857–1952).


Diagnostics

The first physicians to devote entirely to neurology were Moritz Heinrich Romberg,
William A. Hammond William Alexander Hammond (28 August 1828 – 5 January 1900) was an American military physician and neurologist. During the American Civil War he was the eleventh Surgeon General of the United States Army (1862–1864) and the founder of the ...
,
Duchenne de Boulogne Guillaume-Benjamin-Amand Duchenne (de Boulogne) (September 17, 1806 in Boulogne-sur-Mer – September 15, 1875 in Paris) was a French neurologist who revived Galvani's research and greatly advanced the science of electrophysiology. The era of mo ...
, Jean-Martin Charcot and John Hughlings Jackson. Physicians could use the ideas of neurology in practice only if they developed proper tools and procedures for clinical investigation. This happened step by step in the 19th century –
tendon hammer A reflex hammer is a medical instrument used by practitioners to test deep tendon reflexes. Testing for reflexes is an important part of the neurological physical examination in order to detect abnormalities in the central or peripheral nervous s ...
,
ophthalmoscope Ophthalmoscopy, also called funduscopy, is a test that allows a health professional to see inside the fundus of the eye and other structures using an ophthalmoscope (or funduscope). It is done as part of an eye examination and may be done as part ...
, pin and
tuning fork A tuning fork is an acoustic resonator in the form of a two-pronged fork with the prongs ( tines) formed from a U-shaped bar of elastic metal (usually steel). It resonates at a specific constant pitch when set vibrating by striking it agains ...
, syringe and lumbar puncture.
X rays An X-ray, or, much less commonly, X-radiation, is a penetrating form of high-energy electromagnetic radiation. Most X-rays have a wavelength ranging from 10  picometers to 10 nanometers, corresponding to frequencies in the range 30&nbs ...
, the
electro-encephalography Electroencephalography (EEG) is a method to record an electrogram of the spontaneous electrical activity of the brain. The biosignals detected by EEG have been shown to represent the postsynaptic potentials of pyramidal neurons in the neocortex ...
,
angiography Angiography or arteriography is a medical imaging technique used to visualize the inside, or lumen, of blood vessels and organs of the body, with particular interest in the arteries, veins, and the heart chambers. Modern angiography is perfor ...
,
myelography Myelography is a type of radiographic examination that uses a contrast medium to detect pathology of the spinal cord, including the location of a spinal cord injury, cysts, and tumors. Historically the procedure involved the injection of a radioc ...
and CAT scans were to follow. The clinical neurologists correlated their findings after death with those of the neuropathologist. The best known was W.R. Gowers (1845–1915) who owned a major text in two volumes, of a cerebrospinal tract. By the end of the nineteenth century, the connection was established between stroke and hemiplegia, between
trauma Trauma most often refers to: * Major trauma, in physical medicine, severe physical injury caused by an external source * Psychological trauma, a type of damage to the psyche that occurs as a result of a severely distressing event *Traumatic i ...
and paraplegia, between the
spirochaete A spirochaete () or spirochete is a member of the phylum Spirochaetota (), (synonym Spirochaetes) which contains distinctive diderm (double-membrane) gram-negative bacteria, most of which have long, helically coiled (corkscrew-shaped or s ...
and the paralysed demency people who filled the
mental hospital Psychiatric hospitals, also known as mental health hospitals, behavioral health hospitals, are hospitals or wards specializing in the treatment of severe mental disorders, such as schizophrenia, bipolar disorder, eating disorders, dissociative ...
s. The first chemotherapeutic cure of a serious infection was
salvarsan Arsphenamine, also known as Salvarsan or compound 606, is a drug that was introduced at the beginning of the 1910s as the first effective treatment for syphilis, relapsing fever, and African trypanosomiasis. This organoarsenic compound was the fi ...
for syphilis, followed by the induction of fever in
neurosyphilis Neurosyphilis refers to infection of the central nervous system in a patient with syphilis. In the era of modern antibiotics the majority of neurosyphilis cases have been reported in HIV-infected patients. Meningitis is the most common neurologic ...
. The treatment of neurosyphilis became highly effective when antibiotics were introduced.


Neurosurgery


Modern

There was not much advancement in neurosurgery until late 19th early 20th century, when
electrode An electrode is an electrical conductor used to make contact with a nonmetallic part of a circuit (e.g. a semiconductor, an electrolyte, a vacuum or air). Electrodes are essential parts of batteries that can consist of a variety of materials d ...
s were placed on the brain and superficial
tumors A neoplasm () is a type of abnormal and excessive growth of tissue. The process that occurs to form or produce a neoplasm is called neoplasia. The growth of a neoplasm is uncoordinated with that of the normal surrounding tissue, and persists ...
were removed. Neurosurgery, or the premeditated incision into the head for pain relief, has been around for thousands of years, but notable advancements in neurosurgery have only come within the last hundred years. History of electrodes in the brain: In 1878
Richard Caton Richard Caton (1842, Bradford – 1926), of Liverpool, England, was a British physician, physiologist and Lord Mayor of Liverpool who was crucial in discovering the electrical nature of the brain and laid the groundwork for Hans Berger to disco ...
discovered that electrical signals transmitted through an animal's brain. In 1950 Dr. Jose Delgado invented the first electrode that was implanted in an animal's brain, using it to make it run and change direction. In 1972 the
cochlear implant A cochlear implant (CI) is a surgically implanted neuroprosthesis that provides a person who has moderate-to-profound sensorineural hearing loss with sound perception. With the help of therapy, cochlear implants may allow for improved speech unde ...
, a neurological
prosthetic In medicine, a prosthesis (plural: prostheses; from grc, πρόσθεσις, prósthesis, addition, application, attachment), or a prosthetic implant, is an artificial device that replaces a missing body part, which may be lost through trau ...
that allowed deaf people to hear was marketed for commercial use. In 1998 researcher Philip Kennedy implanted the first
brain–computer interface A brain–computer interface (BCI), sometimes called a brain–machine interface (BMI) or smartbrain, is a direct communication pathway between the brain's electrical activity and an external device, most commonly a computer or robotic limb. B ...
(BCI) into a human subject.http://biomed.brown.edu/Courses/BI108/BI108_2005_Groups/03/hist.htm History of tumor removal: In 1879 after locating it via neurological signs alone, Scottish surgeon William Macewen (1848-1924) performed the first successful brain tumor removal. On 25 November 1884 after English physician Alexander Hughes Bennett (1848-1901) used Macewen's technique to locate it, English surgeon Rickman Godlee (1849-1925) performed the first primary brain tumor removal, which differs from Macewen's operation in that Bennett operated on the exposed brain, whereas Macewen operated outside of the "brain proper" via
trepanation Trepanning, also known as trepanation, trephination, trephining or making a burr hole (the verb ''trepan'' derives from Old French from Medieval Latin from Greek , literally "borer, auger"), is a surgical intervention in which a hole is drill ...
. Three years later,
Victor Horsley Sir Victor Alexander Haden Horsley (14 April 1857 – 16 July 1916) was a British scientist and professor. He was born in Kensington, London. Educated at Cranbrook School, Kent, he studied medicine at University College London and in Berlin, G ...
(1857–1916) was the first physician to remove a spinal tumour. On 16 March 1907 Austrian surgeon Hermann Schloffer became the first to successfully remove a
pituitary In vertebrate anatomy, the pituitary gland, or hypophysis, is an endocrine gland, about the size of a chickpea and weighing, on average, in humans. It is a protrusion off the bottom of the hypothalamus at the base of the brain. The hypoph ...
tumor. American surgeon
Harvey Cushing Harvey Williams Cushing (April 8, 1869 – October 7, 1939) was an American neurosurgeon, pathologist, writer, and draftsman. A pioneer of brain surgery, he was the first exclusive neurosurgeon and the first person to describe Cushing's disease. ...
(1869–1939) successfully removed a
pituitary adenoma Pituitary adenomas are tumors that occur in the pituitary gland. Most pituitary tumors are benign, approximately 35% are invasive and just 0.1% to 0.2% are carcinomas.acromegalic in 1909. Treating endocrine hyperfunction by
neurosurgery Neurosurgery or neurological surgery, known in common parlance as brain surgery, is the medical specialty concerned with the surgical treatment of disorders which affect any portion of the nervous system including the brain, spinal cord and pe ...
was a major neurological landmark. Egas Moniz (1874–1955) in Portugal developed a procedure of
leucotomy A lobotomy, or leucotomy, is a form of neurosurgical treatment for psychiatric disorder or neurological disorder (e.g. epilepsy) that involves severing connections in the brain's prefrontal cortex. The surgery causes most of the connections to ...
(now mostly known as lobotomy) to treat severe
psychiatric disorder A mental disorder, also referred to as a mental illness or psychiatric disorder, is a behavioral or mental pattern that causes significant distress or impairment of personal functioning. Such features may be persistent, relapsing and remitt ...
s. Though it is often said that the development of lobotomy was inspired by the case of Phineas Gage, a railroad worker who had an iron bar driven through his left frontal lobe in 1848, the evidence is against this.See Macmillan (2008), Macmillan (2002), and Phineas Gage#Theoretical use and misuse


Modern surgical instruments

The main advancements in neurosurgery came about as a result of highly crafted tools. Modern neurosurgical tools, or instruments, include chisels, curettes, dissectors, distractors, elevators, forceps, hooks, impactors, probes, suction tubes, power tools, and robots. Most of these modern tools, like chisels, elevators, forceps, hooks, impactors, and probes, have been in medical practice for a relatively long time. The main difference of these tools, pre and post advancement in neurosurgery, were the precision in which they were crafted. These tools are crafted with edges that are within a millimeter of desired accuracy. Other tools such as hand held power saws and robots have only recently been commonly used inside of a neurological operating room.


See also

* History of neuraxial anesthesia *
History of neuroscience From the ancient Egyptian mummifications to 18th-century scientific research on "globules" and neurons, there is evidence of neuroscience practice throughout the early periods of history. The early civilizations lacked adequate means to obtain kno ...
* History of neuropsychology *
History of psychology Psychology is defined as "the scientific study of behavior and mental processes". Philosophical interest in the human mind and behavior dates back to the ancient civilizations of Egypt, Persia, Greece, China, and India. Psychology as a field of ...
*
History of psychiatry History (derived ) is the systematic study and the documentation of the human activity. The time period of event before the invention of writing systems is considered prehistory. "History" is an umbrella term comprising past events as well ...
* History of neurophysiology *
List of neurologists and neurosurgeons This is a list of neurologists and neurosurgeons, with their year of birth and death and nationality. This list compiles the names of neurologists and neurosurgeons with a corresponding Wikipedia biographical article, and is not necessarily a refle ...


References


Bibliography

* * * * * * * * * available to browse online at th
National Library of Medicine
* * {{DEFAULTSORT:History of Neurology History of neurology